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A7HL11

- PGK_FERNB

UniProt

A7HL11 - PGK_FERNB

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Protein
Phosphoglycerate kinase
Gene
pgk, Fnod_0739
Organism
Fervidobacterium nodosum (strain ATCC 35602 / DSM 5306 / Rt17-B1)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei36 – 361Substrate By similarity
Binding sitei118 – 1181Substrate By similarity
Binding sitei151 – 1511Substrate By similarity
Binding sitei201 – 2011ATP By similarity
Binding sitei293 – 2931ATP; via carbonyl oxygen By similarity
Binding sitei324 – 3241ATP By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi353 – 3564ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciFNOD381764:GC5M-753-MONOMER.
UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinase (EC:2.7.2.3)
Gene namesi
Name:pgk
Ordered Locus Names:Fnod_0739
OrganismiFervidobacterium nodosum (strain ATCC 35602 / DSM 5306 / Rt17-B1)
Taxonomic identifieri381764 [NCBI]
Taxonomic lineageiBacteriaThermotogaeThermotogalesThermotogaceaeFervidobacterium
ProteomesiUP000002415: Chromosome

Subcellular locationi

Cytoplasm Reviewed prediction UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 400400Phosphoglycerate kinaseUniRule annotation
PRO_1000071470Add
BLAST

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi381764.Fnod_0739.

Structurei

3D structure databases

ProteinModelPortaliA7HL11.
SMRiA7HL11. Positions 2-398.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni21 – 233Substrate binding By similarity
Regioni59 – 624Substrate binding By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227108.
KOiK00927.
OMAiGITHYVP.
OrthoDBiEOG64N9Z0.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A7HL11-1 [UniParc]FASTAAdd to Basket

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MEKLTIRDVD LKGKRVIMRV DFNVPIKDGV VTDDTRIVEA LPTIKYVLEQ    50
GAKVILLTHL GRPKGGPDPK YTVKPAAERL AQLLGKEVKF VPALYGEEVE 100
KAVAELKEGE VLMLENTRFD PGEEKNDLEL AKKWASLADI HVNDAFGTAH 150
RAHSSNVGIA QYIPSVAGFL MEKEIKFLSK ATHNPDKPYV VVLGGAKVSD 200
KIGVITNLLN KADKIIIGGA MMFTFWRALG KQTGNSLVEE DKIDLAKQLL 250
EQAKEKGVEL VIPTDAVCAQ KMEAGVEKKV FTCEEGIPEG WAGYDIGPAS 300
IELIKSKLAD AKTIVWNGPL GVFEIEDFAN GTKAVAEFIA SLTDKGVTTV 350
VGGGDSAAAV SQFGLEKKFS HVSTGGGASL EFLEGKELPG IASIADKKKQ 400
Length:400
Mass (Da):43,110
Last modified:September 11, 2007 - v1
Checksum:i022289550D8EEB90
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000771 Genomic DNA. Translation: ABS60594.1.
RefSeqiYP_001410251.1. NC_009718.1.

Genome annotation databases

EnsemblBacteriaiABS60594; ABS60594; Fnod_0739.
GeneIDi5452283.
KEGGifno:Fnod_0739.
PATRICi21882927. VBIFerNod12464_0778.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000771 Genomic DNA. Translation: ABS60594.1 .
RefSeqi YP_001410251.1. NC_009718.1.

3D structure databases

ProteinModelPortali A7HL11.
SMRi A7HL11. Positions 2-398.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 381764.Fnod_0739.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABS60594 ; ABS60594 ; Fnod_0739 .
GeneIDi 5452283.
KEGGi fno:Fnod_0739.
PATRICi 21882927. VBIFerNod12464_0778.

Phylogenomic databases

eggNOGi COG0126.
HOGENOMi HOG000227108.
KOi K00927.
OMAi GITHYVP.
OrthoDBi EOG64N9Z0.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .
BioCyci FNOD381764:GC5M-753-MONOMER.

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 35602 / DSM 5306 / Rt17-B1.

Entry informationi

Entry nameiPGK_FERNB
AccessioniPrimary (citable) accession number: A7HL11
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: September 11, 2007
Last modified: June 11, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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