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A7HCN7

- PGK_ANADF

UniProt

A7HCN7 - PGK_ANADF

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Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Anaeromyxobacter sp. (strain Fw109-5)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei37 – 371SubstrateUniRule annotation
Binding sitei121 – 1211SubstrateUniRule annotation
Binding sitei154 – 1541SubstrateUniRule annotation
Binding sitei205 – 2051ATPUniRule annotation
Binding sitei296 – 2961ATP; via carbonyl oxygenUniRule annotation
Binding sitei327 – 3271ATPUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi353 – 3564ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciASP404589:GHMT-2304-MONOMER.
UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
Gene namesi
Name:pgkUniRule annotation
Ordered Locus Names:Anae109_2281
OrganismiAnaeromyxobacter sp. (strain Fw109-5)
Taxonomic identifieri404589 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaMyxococcalesCystobacterineaeAnaeromyxobacteraceaeAnaeromyxobacter
ProteomesiUP000006382: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 396396Phosphoglycerate kinasePRO_1000057958Add
BLAST

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi404589.Anae109_2281.

Structurei

3D structure databases

ProteinModelPortaliA7HCN7.
SMRiA7HCN7. Positions 3-395.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni21 – 233Substrate bindingUniRule annotation
Regioni60 – 634Substrate bindingUniRule annotation

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227108.
KOiK00927.
OMAiMSIRYID.
OrthoDBiEOG64N9Z0.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A7HCN7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MALKTIDALD LAGKRVFIRV DFNVPLDEQR RVTDDARIRA ALPTIKHAIQ
60 70 80 90 100
ARAKVILGSH LGRPKGKPDD REKFSLEPAA QRLSELLKQD VILADDCIGD
110 120 130 140 150
GVKKLVRDLK EGQVLLLENL RFHPQEEKND EGFARELATL CDVWVNDAFG
160 170 180 190 200
TAHRAHASTA GMAAFVKEKA AGFLIQKEVE YLGKALGSPE RPFVALIGGA
210 220 230 240 250
KVSDKIKVLE NLIAKADAIC IGGAMAYTFL KAQGVAVGKS LVEEDKLELA
260 270 280 290 300
RQILERAQAR KVDLLLPVDH VCGAEPKDTA ERVVVNDRAI PDGLMGLDIG
310 320 330 340 350
PKTLDRYRQR IVDAKTVFWN GPMGLFEQKP WAEGTFGVAQ AMAQSPAVTV
360 370 380 390
VGGGDSAAAV EEAGLVSKMK HVSTGGGASL EFIEGRVLPG IQVLEG
Length:396
Mass (Da):42,732
Last modified:September 11, 2007 - v1
Checksum:iDADF00E2824FD894
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000769 Genomic DNA. Translation: ABS26483.1.
RefSeqiWP_012097068.1. NC_009675.1.
YP_001379467.1. NC_009675.1.

Genome annotation databases

EnsemblBacteriaiABS26483; ABS26483; Anae109_2281.
GeneIDi5378392.
KEGGiafw:Anae109_2281.
PATRICi20929849. VBIAnaSp113478_2390.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000769 Genomic DNA. Translation: ABS26483.1 .
RefSeqi WP_012097068.1. NC_009675.1.
YP_001379467.1. NC_009675.1.

3D structure databases

ProteinModelPortali A7HCN7.
SMRi A7HCN7. Positions 3-395.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 404589.Anae109_2281.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABS26483 ; ABS26483 ; Anae109_2281 .
GeneIDi 5378392.
KEGGi afw:Anae109_2281.
PATRICi 20929849. VBIAnaSp113478_2390.

Phylogenomic databases

eggNOGi COG0126.
HOGENOMi HOG000227108.
KOi K00927.
OMAi MSIRYID.
OrthoDBi EOG64N9Z0.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .
BioCyci ASP404589:GHMT-2304-MONOMER.

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Fw109-5.

Entry informationi

Entry nameiPGK_ANADF
AccessioniPrimary (citable) accession number: A7HCN7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: September 11, 2007
Last modified: October 29, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3