Reviewed, UniProtKB/Swiss-Prot A7H6S8 (AROC_ANADF)

Names and origin

Protein names

Recommended name:
    Chorismate synthase
    EC=4.2.3.5
Alternative name(s):
    5-enolpyruvylshikimate-3-phosphate phospholyase

Gene names

Name:	aroC
Ordered Locus Names:	Anae109_0206

Organism

Anaeromyxobacter sp. (strain Fw109-5) [Complete proteome] [HAMAP]

Taxonomic identifier

404589 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Myxococcales › Cystobacterineae › Myxococcaceae › Anaeromyxobacter

Protein attributes

Sequence length	381 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300
Cofactor	Reduced flavin By similarity.
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300
Subunit structure	Homotetramer By similarity.
Sequence similarities	Belongs to the chorismate synthase family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	chorismate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 381	381	Chorismate synthase HAMAP MF_00300		PRO_1000071966

Sequences

	Sequence		Length	Mass (Da)
	A7H6S8-1 [UniParc]. Last modified September 11, 2007. Version 1. Checksum: F41B5B7FDA59DCC3	FASTA	381	40,599
	10 20 30 40 50 60 MTIRYLTAGE SHGPGLVAIA EGFPAGLAVD FDEVNRDLRR RQKGYGRGGR QKIEKDEAEF 70 80 90 100 110 120 LAGLRGGVTL GAPIALVVWN KDHESWKDLV SPYARGGRPF TQVRPGHADL AGALKYALTD 130 140 150 160 170 180 ARDVLERASA RSTAVTVALG SLAKQLLARF GVRVSSRVVA IGPRLRHVEE PPTDAERDAI 190 200 210 220 230 240 EASDLHVEDE AVAAEWRALI DAEKARGGSI GGAFDVHATG LPIGLGSHVH PDRRLDARLA 250 260 270 280 290 300 GALCGVQAIR AAEIGDGTQV GRSGPEFHDA IQHDPARGFH RPSNRAGGLE GGMTDGMPLR 310 320 330 340 350 360 VRAYMKPIPT MLTPLATVDL ATREATQARY ERSDVCAVPA AAIVGEAVVA WELANAFLEK 370 380 FGGDALVDVE KAVEAYAARI R

References

[1]

"Complete sequence of Anaeromyxobacter sp. Fw109-5." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Sims D., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. , Lykidis A., Fields M., Richardson P. Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000769 Genomic DNA. Translation: ABS24424.1.
RefSeq	YP_001377408.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A7H6S8.
Genome annotation databases
GeneID	5377073.
GenomeReviews	Gene locus Anae109_0206 in contig CP000769_GR.
KEGG	afw:Anae109_0206.
NMPDR	fig|404589.4.peg.191.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	PPGLGSH.
Family and domain databases
HAMAP	MF_00300. [Tree]
InterPro	IPR000453. Chorismate_synth. IPR020541. Chorismate_synthase_CS. [Graphical view]
PANTHER	PTHR21085. Chorismate_synth. 1 hit.
Pfam	PF01264. Chorismate_synt. 1 hit. [Graphical view]
PIRSF	PIRSF001456. Chorismate_synth. 1 hit.
ProDom	PD002941. Chorismate_synth. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00033. aroC. 1 hit.
PROSITE	PS00787. CHORISMATE_SYNTHASE_1. False negative. PS00788. CHORISMATE_SYNTHASE_2. 1 hit. PS00789. CHORISMATE_SYNTHASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

AROC_ANADF

Accession

Primary (citable) accession number: A7H6S8

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 26, 2008
Last sequence update:	September 11, 2007
Last modified:	November 3, 2009
This is version 17 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)