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A7H6S6 (AROA_ANADF) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-phosphoshikimate 1-carboxyvinyltransferase
EC=2.5.1.19
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthase
Short name=EPSP synthase
Short name=EPSPS
Gene names
Name:aroA
Ordered Locus Names:Anae109_0204
OrganismAnaeromyxobacter sp. (strain Fw109-5) [Complete proteome] [HAMAP]
Taxonomic identifier404589 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Deltaproteobacteria › Myxococcales › Cystobacterineae › Myxococcaceae › Anaeromyxobacter

Protein attributes

Sequence length430 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP MF_00210

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210

Subunit structure

Monomer By similarity. HAMAP MF_00210

Subcellular location

Cytoplasm By similarity HAMAP MF_00210.

Sequence similarities

Belongs to the EPSP synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-phosphoshikimate 1-carboxyvinyltransferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 4304303-phosphoshikimate 1-carboxyvinyltransferase HAMAP MF_00210
PRO_1000058594

Sequences

Sequence LengthMass (Da)Tools
A7H6S6 [UniParc].

Last modified September 11, 2007. Version 1.
Checksum: 4BDC226128C16FD5

FASTA43044,959
        10         20         30         40         50         60 
MTGSLTCRRK GPLRGSIEVP GDKSISHRAL LFGALSTGET RVRGLLDAED VHATRRAVEA 

        70         80         90        100        110        120 
LGATVRAEGE ELVVVPPPAL REPGDVVDCG NSGTSLRLLT GVLSGVPGLS ILTGDASLRR 

       130        140        150        160        170        180 
RPVRRVIEPL RRMGADLSAR DGDRLPPVVV RGRPLRGARH VLEVASAQVK SACLLAGLFA 

       190        200        210        220        230        240 
EGETTVVEPE RSRDHTERML AGMGVPVRVD GLEVTVAPAR PRGGRVDVPG DISSAAFFLC 

       250        260        270        280        290        300 
AAAALPGSEV TVRNLGVNPT RTGLLDVLGA MGAALSRANE REVAGEPRAD VTVRAAALHG 

       310        320        330        340        350        360 
TEIGGAIIPR LIDELPVVMV MATQARGRTV IRDAKELRVK ESDRLASMGE ALARAGAKIE 

       370        380        390        400        410        420 
LFEDGCAIEG PTPLRGVAVQ TRLDHRIAMS MAVAQLLAGG EEVVLDDVAC VATSFPSFFA 

       430 
LLDGLCEGGA

« Hide

References

[1]"Complete sequence of Anaeromyxobacter sp. Fw109-5."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Sims D., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Lykidis A., Fields M., Richardson P.
Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Fw109-5.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000769 Genomic DNA. Translation: ABS24422.1.
RefSeqYP_001377406.1. NC_009675.1.

3D structure databases

ProteinModelPortalA7H6S6.
ModBaseSearch...

Protein-protein interaction databases

STRINGA7H6S6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5374350.
GenomeReviewsGene locus Anae109_0204 in contig CP000769_GR.
KEGGafw:Anae109_0204.
PATRIC20925457. VBIAnaSp113478_0216.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0128.
HOGENOMHBG646626.
OMAVVMVMAT.
ProtClustDBPRK02427.

Family and domain databases

HAMAPMF_00210. EPSP_synth.
[Tree]
InterProIPR001986. Enolpyruvate_Tfrase_dom.
IPR006264. EPSP_synthase.
IPR023193. EPSP_synthase_CS.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
[Graphical view]
Gene3DG3DSA:3.65.10.10. EPSP_synthase. 2 hits.
KOK00800.
PfamPF00275. EPSP_synthase. 1 hit.
[Graphical view]
PIRSFPIRSF000505. EPSPS. 1 hit.
SUPFAMSSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMsTIGR01356. AroA. 1 hit.
PROSITEPS00104. EPSP_SYNTHASE_1. 1 hit.
PS00885. EPSP_SYNTHASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROA_ANADF
AccessionPrimary (citable) accession number: A7H6S6
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: September 11, 2007
Last modified: January 25, 2012
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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