Reviewed, UniProtKB/Swiss-Prot A7H6S6 (AROA_ANADF)

Names and origin

Protein names

Recommended name:
    3-phosphoshikimate 1-carboxyvinyltransferase
    EC=2.5.1.19
Alternative name(s):
    5-enolpyruvylshikimate-3-phosphate synthase
      Short name=EPSP synthase
      Short name=EPSPS

Gene names

Name:	aroA
Ordered Locus Names:	Anae109_0204

Organism

Anaeromyxobacter sp. (strain Fw109-5) [Complete proteome] [HAMAP]

Taxonomic identifier

404589 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Myxococcales › Cystobacterineae › Myxococcaceae › Anaeromyxobacter

Protein attributes

Sequence length	430 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP MF_00210
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210
Subunit structure	Monomer By similarity.
Subcellular location	Cytoplasm Probable.
Sequence similarities	Belongs to the EPSP synthase family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis
Cellular component	Cytoplasm
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3-phosphoshikimate 1-carboxyvinyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 430	430	3-phosphoshikimate 1-carboxyvinyltransferase HAMAP MF_00210		PRO_1000058594

Sequences

	Sequence		Length	Mass (Da)
	A7H6S6-1 [UniParc]. Last modified September 11, 2007. Version 1. Checksum: 4BDC226128C16FD5	FASTA	430	44,959
	10 20 30 40 50 60 MTGSLTCRRK GPLRGSIEVP GDKSISHRAL LFGALSTGET RVRGLLDAED VHATRRAVEA 70 80 90 100 110 120 LGATVRAEGE ELVVVPPPAL REPGDVVDCG NSGTSLRLLT GVLSGVPGLS ILTGDASLRR 130 140 150 160 170 180 RPVRRVIEPL RRMGADLSAR DGDRLPPVVV RGRPLRGARH VLEVASAQVK SACLLAGLFA 190 200 210 220 230 240 EGETTVVEPE RSRDHTERML AGMGVPVRVD GLEVTVAPAR PRGGRVDVPG DISSAAFFLC 250 260 270 280 290 300 AAAALPGSEV TVRNLGVNPT RTGLLDVLGA MGAALSRANE REVAGEPRAD VTVRAAALHG 310 320 330 340 350 360 TEIGGAIIPR LIDELPVVMV MATQARGRTV IRDAKELRVK ESDRLASMGE ALARAGAKIE 370 380 390 400 410 420 LFEDGCAIEG PTPLRGVAVQ TRLDHRIAMS MAVAQLLAGG EEVVLDDVAC VATSFPSFFA 430 LLDGLCEGGA

References

[1]

"Complete sequence of Anaeromyxobacter sp. Fw109-5." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Sims D., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. , Lykidis A., Fields M., Richardson P. Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000769 Genomic DNA. Translation: ABS24422.1.
RefSeq	YP_001377406.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A7H6S6.
Genome annotation databases
GeneID	5374350.
GenomeReviews	Gene locus Anae109_0204 in contig CP000769_GR.
KEGG	afw:Anae109_0204.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	IEVPPER.
Family and domain databases
HAMAP	MF_00210. [Tree]
InterPro	IPR016228. EPSP_synthase. IPR001986. EPSP_synthase_core. IPR006264. EPSP_synthase_subgroup. [Graphical view]
Gene3D	G3DSA:3.65.10.10. EPSP_synthase. 2 hits.
Pfam	PF00275. EPSP_synthase. 1 hit. [Graphical view]
PIRSF	PIRSF000505. EPSPS. 1 hit.
ProDom	PD001867. EPSP_synth. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR01356. aroA. 1 hit.
PROSITE	PS00104. EPSP_SYNTHASE_1. 1 hit. PS00885. EPSP_SYNTHASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

AROA_ANADF

Accession

Primary (citable) accession number: A7H6S6

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	September 11, 2007
Last modified:	November 3, 2009
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)