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Protein

tRNA pseudouridine synthase D

Gene

truD

Organism
Campylobacter jejuni subsp. doylei (strain ATCC BAA-1458 / RM4099 / 269.97)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(13) = tRNA pseudouridine(13).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei85NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

tRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase DUniRule annotation (EC:5.4.99.27UniRule annotation)
Alternative name(s):
tRNA pseudouridine(13) synthaseUniRule annotation
tRNA pseudouridylate synthase DUniRule annotation
tRNA-uridine isomerase DUniRule annotation
Gene namesi
Name:truDUniRule annotation
Ordered Locus Names:JJD26997_1792
OrganismiCampylobacter jejuni subsp. doylei (strain ATCC BAA-1458 / RM4099 / 269.97)
Taxonomic identifieri360109 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter
Proteomesi
  • UP000002302 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000847311 – 372tRNA pseudouridine synthase DAdd BLAST372

Structurei

3D structure databases

ProteinModelPortaliA7H5G6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini160 – 330TRUDUniRule annotationAdd BLAST171

Sequence similaritiesi

Belongs to the pseudouridine synthase TruD family.UniRule annotation
Contains 1 TRUD domain.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000224848.
KOiK06176.
OMAiGNRFFMR.
OrthoDBiPOG091H03KK.

Family and domain databases

HAMAPiMF_01082. TruD. 1 hit.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR001656. PsdUridine_synth_TruD.
IPR020119. PsdUridine_synth_TruD_CS.
IPR011760. PsdUridine_synth_TruD_insert.
[Graphical view]
PANTHERiPTHR13326. PTHR13326. 1 hit.
PfamiPF01142. TruD. 2 hits.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 2 hits.
TIGRFAMsiTIGR00094. tRNA_TruD_broad. 1 hit.
PROSITEiPS50984. TRUD. 1 hit.
PS01268. UPF0024. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A7H5G6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLAEENTIF KPLYSLKHSS INAYFSKNSD DFVVRERPLY EFSGKGEHLI
60 70 80 90 100
LHINKKDLST NEALKILSEQ SGVKMRDFGY AGLKDKQGST FQYLSIPKKF
110 120 130 140 150
ESFLSNFSHS KLKILETFTH ENKLRIGHLK GNSFFIRLKK VMPSDALKLE
160 170 180 190 200
QVLMNLDKQG FANYFGYQRF GKFGDNYKEG LEILRGKKMK NIKMKEFLIS
210 220 230 240 250
AFQSDLFNRY LSKRVELSHF ANDFSEKELL QIYKISKEEA KELKKQEQFF
260 270 280 290 300
KLLKGEVLGH YPFGKCFLCE DLSAELERFR ARDISAMGLL IGTKAYETGE
310 320 330 340 350
GLALNLENEI FKDALEFKAK MQGSRRFMWR YLEELKWRYD EEKAHFCIEF
360 370
FLQKGSYATV VLEEILHKNL PE
Length:372
Mass (Da):43,593
Last modified:September 11, 2007 - v1
Checksum:iA04B27831A9AA592
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000768 Genomic DNA. Translation: ABS43609.1.
RefSeqiWP_011990772.1. NC_009707.1.

Genome annotation databases

EnsemblBacteriaiABS43609; ABS43609; JJD26997_1792.
KEGGicjd:JJD26997_1792.
PATRICi20049262. VBICamJej122183_1775.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000768 Genomic DNA. Translation: ABS43609.1.
RefSeqiWP_011990772.1. NC_009707.1.

3D structure databases

ProteinModelPortaliA7H5G6.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABS43609; ABS43609; JJD26997_1792.
KEGGicjd:JJD26997_1792.
PATRICi20049262. VBICamJej122183_1775.

Phylogenomic databases

HOGENOMiHOG000224848.
KOiK06176.
OMAiGNRFFMR.
OrthoDBiPOG091H03KK.

Family and domain databases

HAMAPiMF_01082. TruD. 1 hit.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR001656. PsdUridine_synth_TruD.
IPR020119. PsdUridine_synth_TruD_CS.
IPR011760. PsdUridine_synth_TruD_insert.
[Graphical view]
PANTHERiPTHR13326. PTHR13326. 1 hit.
PfamiPF01142. TruD. 2 hits.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 2 hits.
TIGRFAMsiTIGR00094. tRNA_TruD_broad. 1 hit.
PROSITEiPS50984. TRUD. 1 hit.
PS01268. UPF0024. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiTRUD_CAMJD
AccessioniPrimary (citable) accession number: A7H5G6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: September 11, 2007
Last modified: November 2, 2016
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.