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Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Campylobacter jejuni subsp. doylei (strain ATCC BAA-1458 / RM4099 / 269.97)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate.UniRule annotation
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Phosphoglycerate kinase (pgk)
  3. 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (gpmI)
  4. Enolase (eno)
  5. Pyruvate kinase (pyk)
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei38SubstrateUniRule annotation1
Binding sitei119SubstrateUniRule annotation1
Binding sitei152SubstrateUniRule annotation1
Binding sitei205ATPUniRule annotation1
Binding sitei296ATP; via carbonyl oxygenUniRule annotation1
Binding sitei327ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi353 – 356ATPUniRule annotation4

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase
Biological processGlycolysis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCJEJ360109:G1G9I-1619-MONOMER
UniPathwayiUPA00109; UER00185

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
Gene namesi
Name:pgkUniRule annotation
Ordered Locus Names:JJD26997_1736
OrganismiCampylobacter jejuni subsp. doylei (strain ATCC BAA-1458 / RM4099 / 269.97)
Taxonomic identifieri360109 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter
Proteomesi
  • UP000002302 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10002033261 – 400Phosphoglycerate kinaseAdd BLAST400

Proteomic databases

PRIDEiA7H5C5

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliA7H5C5
SMRiA7H5C5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni22 – 24Substrate bindingUniRule annotation3
Regioni61 – 64Substrate bindingUniRule annotation4

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000227107
KOiK00927
OMAiDMIFDIG
OrthoDBiPOG091H00YN

Family and domain databases

Gene3Di3.40.50.1260, 2 hits
HAMAPiMF_00145 Phosphoglyc_kinase, 1 hit
InterProiView protein in InterPro
IPR001576 Phosphoglycerate_kinase
IPR015824 Phosphoglycerate_kinase_N
IPR036043 Phosphoglycerate_kinase_sf
PANTHERiPTHR11406 PTHR11406, 1 hit
PfamiView protein in Pfam
PF00162 PGK, 1 hit
PIRSFiPIRSF000724 Pgk, 1 hit
PRINTSiPR00477 PHGLYCKINASE
SUPFAMiSSF53748 SSF53748, 1 hit

Sequencei

Sequence statusi: Complete.

A7H5C5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDIISIKDI DLAKKKIFIR CDFNVPQDDF LNITDDRRIR SAIPTIRYCL
60 70 80 90 100
DNGCSVILAS HLGRPKEISS KYSLEPVSKR LARLLDKEII MAKDIIGEDA
110 120 130 140 150
KTKAMNLKAG EILLLENLRF EKGETKNDEN LAKELASMVQ VYINDAFGVC
160 170 180 190 200
HRAHSSVEAI TKFFDEKHKG AGFLLQKEID FASNLIKHPA RPFVAVVGGS
210 220 230 240 250
KVSGKLQALT NLLPKVDKLI IGGGMAFTFL KALGYDIGNS LLEEELLEEA
260 270 280 290 300
NKILTKGKNL GVKIYLPVDV VAAPACSQDA PMKFVPVQEI PNGWMGLDIG
310 320 330 340 350
PASVRLFKEV ISDAQTIWWN GPMGVFEIDK FSKGSIKMSH YISEGHATSV
360 370 380 390 400
VGGGDTADVV ARAGDADEMT FISTGGGASL ELIEGKELPG VKALRSKENE
Length:400
Mass (Da):43,650
Last modified:September 11, 2007 - v1
Checksum:iBCF7023A179A5D39
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000768 Genomic DNA Translation: ABS43352.1

Genome annotation databases

EnsemblBacteriaiABS43352; ABS43352; JJD26997_1736
KEGGicjd:JJD26997_1736

Similar proteinsi

Entry informationi

Entry nameiPGK_CAMJD
AccessioniPrimary (citable) accession number: A7H5C5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: September 11, 2007
Last modified: March 28, 2018
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
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Main funding by: National Institutes of Health