Reviewed, UniProtKB/Swiss-Prot A7H4D5 (ACKA_CAMJD)

Names and origin

Protein names

Recommended name:
    Acetate kinase
    EC=2.7.2.1
Alternative name(s):
    Acetokinase

Gene names

Name:	ackA
Ordered Locus Names:	JJD26997_1318

Organism

Campylobacter jejuni subsp. doylei (strain ATCC BAA-1458 / RM4099 / 269.97) [Complete proteome] [HAMAP]

Taxonomic identifier

360109 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter

Protein attributes

Sequence length	396 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020 ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the acetokinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	organic acid metabolic process Inferred from electronic annotation. Source: InterPro phosphorylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 396	396	Acetate kinase HAMAP MF_00020		PRO_1000002216

Sequences

	Sequence		Length	Mass (Da)
	A7H4D5-1 [UniParc]. Last modified September 11, 2007. Version 1. Checksum: B670F79755F6FDF2	FASTA	396	44,009
	10 20 30 40 50 60 MKILVLNSGS SSIKFKFFDN KIIKASGLVE KIGEQNSKVI LKNVLNNESF ERELTINNHE 70 80 90 100 110 120 EGLSIVNELF KESGILADLN TLDGCGHRIV HGGRNLSEHC LVDDYVLKEI DRVSIFAPLH 130 140 150 160 170 180 NPAHLAGIKT MIKAAPSVAN VAIFDTAFHR TMPDFAYMYA LPYDFYDKHN IRRYGFHGTS 190 200 210 220 230 240 HAFVSSRAAS LLEKDKSELN VISAHLGNGA SVCAIEKGKS VDTSMGFTPL EGLVMGTRCG 250 260 270 280 290 300 DLDPAILPFI SHLKGLTIEE IDTLMNKKSG VYGICGYNDF RDIEREIEQG NDKARLALDM 310 320 330 340 350 360 FCYRLVKYIG AYFAVLPKTD AIVFTGGIGE NDSLVRQKVC ERLAHLGIEL DFELNKQRIS 370 380 390 GERMINHANS KVKVLVIPTD EELEIARITE ELIGKN

References

[1]

"Complete genome sequence of Campylobacter jejuni subsp doylei 269.97 isolated from human blood." Fouts D.E., Mongodin E.F., Puiu D., Sebastian Y., Miller W.G., Mandrell R.E., Lastovica A.J., Nelson K.E. Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000768 Genomic DNA. Translation: ABS44554.1.
RefSeq	YP_001398365.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A7H4D5.
Genome annotation databases
GeneID	5388911.
GenomeReviews	Gene locus JJD26997_1318 in contig CP000768_GR.
KEGG	cjd:JJD26997_1318.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	NYEKESA.
Family and domain databases
HAMAP	MF_00020. [Tree]
InterPro	IPR000890. Acetate/butyrate_kinase. IPR004372. AckA. [Graphical view]
PANTHER	PTHR21060. Acetate_kin. 1 hit. PTHR21060:SF11. AckA. 1 hit.
Pfam	PF00871. Acetate_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000722. Acetate_prop_kin. 1 hit.
PRINTS	PR00471. ACETATEKNASE.
TIGRFAMs	TIGR00016. ackA. 1 hit.
PROSITE	PS01075. ACETATE_KINASE_1. 1 hit. PS01076. ACETATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACKA_CAMJD

Accession

Primary (citable) accession number: A7H4D5

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	September 11, 2007
Last modified:	November 3, 2009
This is version 14 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)