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Protein

RNA pyrophosphohydrolase

Gene

rppH

Organism
Campylobacter jejuni subsp. doylei (strain ATCC BAA-1458 / RM4099 / 269.97)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.UniRule annotation

Cofactori

a divalent metal cationUniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
RNA pyrophosphohydrolaseUniRule annotation (EC:3.6.1.-UniRule annotation)
Alternative name(s):
(Di)nucleoside polyphosphate hydrolaseUniRule annotation
Gene namesi
Name:rppHUniRule annotation
Synonyms:nudHUniRule annotation
Ordered Locus Names:JJD26997_1088
OrganismiCampylobacter jejuni subsp. doylei (strain ATCC BAA-1458 / RM4099 / 269.97)
Taxonomic identifieri360109 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter
Proteomesi
  • UP000002302 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000789571 – 156RNA pyrophosphohydrolaseAdd BLAST156

Structurei

3D structure databases

ProteinModelPortaliA7H3U9.
SMRiA7H3U9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 148Nudix hydrolaseUniRule annotationAdd BLAST143

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi43 – 64Nudix boxAdd BLAST22

Sequence similaritiesi

Belongs to the Nudix hydrolase family. RppH subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000066722.
KOiK08311.
OMAiRPCVGIM.
OrthoDBiPOG091H0392.

Family and domain databases

CDDicd03671. Ap4A_hydrolase_plant_like. 1 hit.
HAMAPiMF_00298. Nudix_RppH. 1 hit.
InterProiView protein in InterPro
IPR020476. Nudix_hydrolase.
IPR020084. NUDIX_hydrolase_CS.
IPR000086. NUDIX_hydrolase_dom.
IPR015797. NUDIX_hydrolase_dom-like.
IPR022927. RppH.
PfamiView protein in Pfam
PF00293. NUDIX. 1 hit.
PRINTSiPR00502. NUDIXFAMILY.
SUPFAMiSSF55811. SSF55811. 1 hit.
PROSITEiView protein in PROSITE
PS51462. NUDIX. 1 hit.
PS00893. NUDIX_BOX. 1 hit.

Sequencei

Sequence statusi: Complete.

A7H3U9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENEKNYRPN VAAIVLSSSY PFECKIFIAK RSDMDNIWQF PQGGIDKGES
60 70 80 90 100
AKNALFRELK EEIGTDEVEI IAEYPEWLSY DFPGKIVKKM YPYDGQIQKY
110 120 130 140 150
FLVRLKHGAT ININTKHPEF DDYQFVSVKQ IFEMINHFKK NIYVKVIKYF

EEKGYI
Length:156
Mass (Da):18,470
Last modified:September 11, 2007 - v1
Checksum:iD2C27C4D8E2680B9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000768 Genomic DNA. Translation: ABS44569.1.
RefSeqiWP_011990267.1. NC_009707.1.

Genome annotation databases

EnsemblBacteriaiABS44569; ABS44569; JJD26997_1088.
KEGGicjd:JJD26997_1088.

Similar proteinsi

Entry informationi

Entry nameiRPPH_CAMJD
AccessioniPrimary (citable) accession number: A7H3U9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: September 11, 2007
Last modified: August 30, 2017
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families