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Protein

tRNA pseudouridine synthase B

Gene

truB

Organism
Campylobacter jejuni subsp. doylei (strain ATCC BAA-1458 / RM4099 / 269.97)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei38 – 381NucleophileUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

tRNA processing

Enzyme and pathway databases

BioCyciCJEJ360109:GJDG-599-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase BUniRule annotation (EC:5.4.99.25UniRule annotation)
Alternative name(s):
tRNA pseudouridine(55) synthaseUniRule annotation
Short name:
Psi55 synthaseUniRule annotation
tRNA pseudouridylate synthaseUniRule annotation
tRNA-uridine isomeraseUniRule annotation
Gene namesi
Name:truBUniRule annotation
Ordered Locus Names:JJD26997_0620
OrganismiCampylobacter jejuni subsp. doylei (strain ATCC BAA-1458 / RM4099 / 269.97)
Taxonomic identifieri360109 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter
Proteomesi
  • UP000002302 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 272272tRNA pseudouridine synthase BPRO_1000084565Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliA7H2Q5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000231225.
KOiK03177.
OMAiDYSFLIP.
OrthoDBiPOG091H02G9.

Family and domain databases

HAMAPiMF_01080. TruB_bact. 1 hit.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR002501. PsdUridine_synth_N.
IPR014780. tRNA_psdUridine_synth_TruB.
[Graphical view]
PANTHERiPTHR13767. PTHR13767. 1 hit.
PfamiPF01509. TruB_N. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00431. TruB. 1 hit.

Sequencei

Sequence statusi: Complete.

A7H2Q5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKIFAAFKP RGLSSNSFLS TLKKKYKNKK AGYSGTLDPF AKGVLIVAFG
60 70 80 90 100
QYAKLFRFLK KTPKTYKATL WLGVYSLSLD DQNIKKIQNI KEFDLAILKQ
110 120 130 140 150
IIDQMQGIIS YTPPQFSAKR INGTRAYELA KKGIEANLKP CQMEVFDCKI
160 170 180 190 200
LSYNHPFLNI EITVSEGAYI RSYCELFARK LGINATLSSL ERIKEGKFVY
210 220 230 240 250
NNEKSLNVLK YINLKPNFIK DLNKLENGAK IFVEELEFHD EGDYYIETEK
260 270
YFSIINIKEN TVKYLLNKVE KC
Length:272
Mass (Da):31,350
Last modified:September 11, 2007 - v1
Checksum:i2075DF9C6A1FD6ED
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000768 Genomic DNA. Translation: ABS43738.1.
RefSeqiWP_011989896.1. NC_009707.1.

Genome annotation databases

EnsemblBacteriaiABS43738; ABS43738; JJD26997_0620.
KEGGicjd:JJD26997_0620.
PATRICi20046887. VBICamJej122183_0617.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000768 Genomic DNA. Translation: ABS43738.1.
RefSeqiWP_011989896.1. NC_009707.1.

3D structure databases

ProteinModelPortaliA7H2Q5.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABS43738; ABS43738; JJD26997_0620.
KEGGicjd:JJD26997_0620.
PATRICi20046887. VBICamJej122183_0617.

Phylogenomic databases

HOGENOMiHOG000231225.
KOiK03177.
OMAiDYSFLIP.
OrthoDBiPOG091H02G9.

Enzyme and pathway databases

BioCyciCJEJ360109:GJDG-599-MONOMER.

Family and domain databases

HAMAPiMF_01080. TruB_bact. 1 hit.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR002501. PsdUridine_synth_N.
IPR014780. tRNA_psdUridine_synth_TruB.
[Graphical view]
PANTHERiPTHR13767. PTHR13767. 1 hit.
PfamiPF01509. TruB_N. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00431. TruB. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiTRUB_CAMJD
AccessioniPrimary (citable) accession number: A7H2Q5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: September 11, 2007
Last modified: September 7, 2016
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.