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Protein

60 kDa chaperonin

Gene

groL

Organism
Campylobacter jejuni subsp. doylei (strain ATCC BAA-1458 / RM4099 / 269.97)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperoninUniRule annotation
Alternative name(s):
GroEL proteinUniRule annotation
Protein Cpn60UniRule annotation
Gene namesi
Name:groLUniRule annotation
Synonyms:groELUniRule annotation
Ordered Locus Names:JJD26997_0509
OrganismiCampylobacter jejuni subsp. doylei (strain ATCC BAA-1458 / RM4099 / 269.97)
Taxonomic identifieri360109 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter
Proteomesi
  • UP000002302 Componenti: Chromosome

Subcellular locationi

A7H2F8:
  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000257661 – 54560 kDa chaperoninAdd BLAST545

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliA7H2F8.
SMRiA7H2F8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000076290.
KOiK04077.
OMAiTDTDKME.
OrthoDBiPOG091H00E7.

Family and domain databases

CDDicd03344. GroEL. 1 hit.
Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPiMF_00600. CH60. 1 hit.
InterProiView protein in InterPro
IPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
IPR027410. TCP-1-like_intermed.
PANTHERiPTHR11353. PTHR11353. 1 hit.
PfamiView protein in Pfam
PF00118. Cpn60_TCP1. 1 hit.
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF48592. SSF48592. 2 hits.
SSF52029. SSF52029. 1 hit.
SSF54849. SSF54849. 1 hit.
TIGRFAMsiTIGR02348. GroEL. 1 hit.
PROSITEiView protein in PROSITE
PS00296. CHAPERONINS_CPN60. 1 hit.

Sequencei

Sequence statusi: Complete.

A7H2F8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKEIIFSDE ARNKLYEGVK KLNDAVKVTM GPRGRNVLIQ KSFGAPSITK
60 70 80 90 100
DGVSVAKEVE LKDSLENMGA SLVREVASKT ADQAGDGTTT ATVLAHAIFK
110 120 130 140 150
EGLRNITAGA NPIEVKRGMD KACEAIVAEL KKLSREVKDK KEIAQVATIS
160 170 180 190 200
ANSDEKIGNL IADAMEKVGK DGVITVEEAK SINDELNVVE GMQFDRGYLS
210 220 230 240 250
PYFITNAEKM TVELSSPYIL LFDKKIANLK DLLPVLEQIQ KTGKPLLIIA
260 270 280 290 300
EDIEGEALAT LVVNKLRGVL NISAVKAPGF GDRRKAMLED IAILTGGEVI
310 320 330 340 350
SEELGRTLES ATIQDLGQAS SVIIDKDNTT VVNGAGEKAN IDARVNQIKA
360 370 380 390 400
QIAETTSDYD REKLQERLAK LSGGVAVIKV GAATETEMKE KKDRVDDALS
410 420 430 440 450
ATKAAVEEGI VIGGGAALIK AKAKIKLDLQ GDEAIGAAIV ERALRAPLRQ
460 470 480 490 500
IAENAGFDAG VVVNSVENAK DENTGFDAAK GEYVNMLESG IIDPVKVERV
510 520 530 540
ALLNAVSVAS MLLTTEATIS EIKEDKPAMP DMSGMGGMGG MGGMM
Length:545
Mass (Da):57,896
Last modified:September 11, 2007 - v1
Checksum:i34211136375D450F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000768 Genomic DNA. Translation: ABS43566.1.
RefSeqiWP_011989809.1. NC_009707.1.

Genome annotation databases

EnsemblBacteriaiABS43566; ABS43566; JJD26997_0509.
KEGGicjd:JJD26997_0509.

Similar proteinsi

Entry informationi

Entry nameiCH60_CAMJD
AccessioniPrimary (citable) accession number: A7H2F8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: September 11, 2007
Last modified: October 25, 2017
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families