A7H291 (DCD_CAMJD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	JJD26997_0430

Organism

Campylobacter jejuni subsp. doylei (strain ATCC BAA-1458 / RM4099 / 269.97) [Complete proteome] [HAMAP]

Taxonomic identifier

360109 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter

Protein attributes

Sequence length	186 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 186	186	Deoxycytidine triphosphate deaminase HAMAP MF_00146		PRO_1000009702

Sequences

	Sequence		Length	Mass (Da)
	A7H291 [UniParc]. Last modified September 11, 2007. Version 1. Checksum: 6FBAB6A5A449AA48	FASTA	186	20,647
	10 20 30 40 50 60 MGLKADNWIR KMALEHKMIE PFCEANIGKG VVSYGLSSYG YDICVGREFK IFTNVNSTVV 70 80 90 100 110 120 DPKNFVEENV VDFEGDVCIV PANSFALART IEYFKMPDDV LAICLGKSTY ARCGIIVNVT 130 140 150 160 170 180 PFEPGFEGHI TIEISNTTPL PAKIYANEGI AQVLFLQGDE KCDTTYKDKK GKYQAQTGIT LPRILK

References

[1]

"Complete genome sequence of Campylobacter jejuni subsp doylei 269.97 isolated from human blood." Fouts D.E., Mongodin E.F., Puiu D., Sebastian Y., Miller W.G., Mandrell R.E., Lastovica A.J., Nelson K.E. Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-1458 / RM4099 / 269.97.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000768 Genomic DNA. Translation: ABS43852.1.
RefSeq	YP_001397621.1. NC_009707.1.
3D structure databases
ProteinModelPortal	A7H291.
ModBase	Search...
Protein-protein interaction databases
STRING	A7H291.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5388743.
GenomeReviews	Gene locus JJD26997_0430 in contig CP000768_GR.
KEGG	cjd:JJD26997_0430.
PATRIC	20046495. VBICamJej122183_0424.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0717.
HOGENOM	HBG553199.
OMA	MEYFRIP.
ProtClustDB	PRK00416.
Enzyme and pathway databases
BioCyc	CJEJ360109:JJD26997_0430-MONOMER.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase. [Tree]
InterPro	IPR011962. dCTP_deam. IPR008180. dUTP_pyroPase. [Graphical view]
KO	K01494.
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. DCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_CAMJD

Accession

Primary (citable) accession number: A7H291

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	September 11, 2007
Last modified:	December 14, 2011
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program