Reviewed, UniProtKB/Swiss-Prot A7H0H0 (DCD_CAMC5)

Names and origin

Protein names

Recommended name:
    Deoxycytidine triphosphate deaminase
      Short name=dCTP deaminase
    EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	Ccur92_16580
ORF Names:	CCV52592_0559

Organism

Campylobacter curvus (strain 525.92) [Complete proteome] [HAMAP]

Taxonomic identifier

360105 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter

Protein attributes

Sequence length	186 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 186	186	Deoxycytidine triphosphate deaminase HAMAP MF_00146		PRO_1000009699

Sequences

	Sequence		Length	Mass (Da)
	A7H0H0-1 [UniParc]. Last modified September 11, 2007. Version 1. Checksum: 1E0156C61A49ABC9	FASTA	186	20,520
	10 20 30 40 50 60 MGLKSDAWIR KMSHEKAMIV PFAEEQVGRG VVSYGVSSYG YDIRVGDEFK IFTNIGGTVV 70 80 90 100 110 120 DPKNFDEKNV VDFKGDVCIV PPNSFALART IEYFNMPDNV LAICLGKSTY ARCGIIVNVT 130 140 150 160 170 180 PFEPGFKGHI TIEISNTTPL PAKIYANEGI AQVLFIEGDE PCEVTYADKK GKYQAQEGIT LPRILK

References

[1]	"Genome sequence of Campylobacter curvus 525.92 isolated from human feces." Fouts D.E., Mongodin E.F., Puiu D., Sebastian Y., Miller W.G., Mandrell R.E., Lastovica A.J., Nelson K.E. Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000767 Genomic DNA. Translation: EAU01415.1.
RefSeq	YP_001408962.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A7H0H0.
Genome annotation databases
GeneID	5407013.
GenomeReviews	Gene locus Ccur92_16580 in contig CP000767_GR.
KEGG	ccv:CCV52592_0559.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	CAQVLFF.
Family and domain databases
HAMAP	MF_00146. [Tree]
InterPro	IPR011962. dCTP_deam. IPR008180. DeoxyUTP_pyroPase_dom. [Graphical view]
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
ProDom	PD004900. dCTP_deaminase. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR02274. dCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_CAMC5

Accession

Primary (citable) accession number: A7H0H0

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	September 11, 2007
Last modified:	November 3, 2009
This is version 14 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)