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A7H081 (A7H081_CAMC5) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
1-deoxy-D-xylulose-5-phosphate synthase HAMAP MF_00315
EC=2.2.1.7 HAMAP MF_00315
Alternative name(s):
1-deoxyxylulose-5-phosphate synthase HAMAP MF_00315
Gene names
Name:dxs HAMAP MF_00315 EMBL EAU01086.1
Ordered Locus Names:Ccur92_15690
ORF Names:CCV52592_1671 EMBL EAU01086.1
OrganismCampylobacter curvus (strain 525.92) [Complete proteome] [HAMAP]
Taxonomic identifier360105 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter

Protein attributes

Sequence length609 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) By similarity. HAMAP MF_00315 SAAS SAAS001017

Catalytic activity

Pyruvate + D-glyceraldehyde 3-phosphate = 1-deoxy-D-xylulose 5-phosphate + CO2. HAMAP MF_00315 SAAS SAAS001017

Cofactor

Binds 1 thiamine pyrophosphate per subunit By similarity. HAMAP MF_00315 SAAS SAAS001017

Pathway

Metabolic intermediate biosynthesis; 1-deoxy-D-xylulose 5-phosphate biosynthesis; 1-deoxy-D-xylulose 5-phosphate from D-glyceraldehyde 3-phosphate and pyruvate: step 1/1. HAMAP MF_00315 SAAS SAAS001017

Subunit structure

Homodimer By similarity. HAMAP MF_00315 SAAS SAAS001017

Sequence similarities

Belongs to the transketolase family. DXPS subfamily. HAMAP MF_00315

Sequences

Sequence LengthMass (Da)Tools
A7H081 [UniParc].

Last modified September 11, 2007. Version 1.
Checksum: 9AE8BB9B7C93CFDB

FASTA60967,157
        10         20         30         40         50         60 
MTDLNVKNLD LSGLEELCHK LRDKILTTVS KNGGHLSSNI GAVEIIVAMH YVFDAKNDPF 

        70         80         90        100        110        120 
IFDVSHQSYA HKLLTDRWES FESLRKFGGI SGYTKPSESK FDYFIAGHSS TSISLAVGAA 

       130        140        150        160        170        180 
KAINLKHEQR LPVAVIGDGS LSGGMAYEAL NELGDRKYPC VIILNDNEMS ISKPIGALSK 

       190        200        210        220        230        240 
YLSQMMAGQF YQKFKGRVEK FLSYMPDSAA YMARRMEEGI RLITPGMFFE ELGLEYIGPV 

       250        260        270        280        290        300 
DGHDLGSLIS TFETARSMKK PVIVHVQTLK GKGYEFAEGY YANWHGVGPF DLKSGEFIKK 

       310        320        330        340        350        360 
QSNKSATAIF SEHLLKMAGE HEDIVGVTAA MPTGTGMDAL IEKFPDRFWD VAIAEQHAVT 

       370        380        390        400        410        420 
SMAAMAKEGF KPFVAIYSTF MQRAYDQLIH DACIMNSNMT FAMDRAGIVG EDGETHQGAF 

       430        440        450        460        470        480 
DISFFNAIPN VVMFAPRCER SMKMAMEFAY AYKGVSAFRY PRGAFILADE FEAKDLRLGK 

       490        500        510        520        530        540 
GEILAKGRGE VALIGYGNGV GKANTVRNLI SSNIDATLVD LVFAKPLDSE LLLELADKCK 

       550        560        570        580        590        600 
KWYVISDSAK KGGIGEILSA FLQENKILDV SVKSFEYDDT FIPHGSTADV ERNLGISAEQ 


IAQKLLDDN

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References

[1]"Genome sequence of Campylobacter curvus 525.92 isolated from human feces."
Fouts D.E., Mongodin E.F., Puiu D., Sebastian Y., Miller W.G., Mandrell R.E., Lastovica A.J., Nelson K.E.
Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000767 Genomic DNA. Translation: EAU01086.1.
RefSeqYP_001408873.1. NC_009715.1.

3D structure databases

ProteinModelPortalA7H081.
ModBaseSearch...

Protein-protein interaction databases

STRINGA7H081.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5406482.
GenomeReviewsGene locus Ccur92_15690 in contig CP000767_GR.
KEGGccv:CCV52592_1671.
PATRIC20033737. VBICamCur47627_1653.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1154.
HOGENOMHBG571647.
OMAYPRGAFI.
ProtClustDBPRK05444.

Family and domain databases

HAMAPMF_00315. DXP_synth.
[Tree]
InterProIPR001017. DH_E1.
IPR005477. Dxylulose-5-P_synthase.
IPR009014. Transketo_C/Pyr-ferredox_oxred.
IPR015941. Transketolase-like_C.
IPR005475. Transketolase-like_Pyr-bd.
IPR020826. Transketolase_BS.
IPR005476. Transketolase_C.
IPR005474. Transketolase_N.
[Graphical view]
Gene3DG3DSA:3.40.50.920. Transketo_C_like. 1 hit.
KOK01662.
PfamPF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
PF02780. Transketolase_C. 1 hit.
[Graphical view]
SMARTSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMSSF52922. Transketo_C_like. 1 hit.
TIGRFAMsTIGR00204. Dxs. 1 hit.
PROSITEPS00801. TRANSKETOLASE_1. 1 hit.
PS00802. TRANSKETOLASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA7H081_CAMC5
AccessionPrimary (citable) accession number: A7H081
Entry history
Integrated into UniProtKB/TrEMBL: September 11, 2007
Last sequence update: September 11, 2007
Last modified: December 14, 2011
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info