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Protein

60 kDa chaperonin

Gene

groL

Organism
Campylobacter curvus (strain 525.92)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperoninUniRule annotation
Alternative name(s):
GroEL proteinUniRule annotation
Protein Cpn60UniRule annotation
Gene namesi
Name:groLUniRule annotation
Synonyms:groELUniRule annotation
Ordered Locus Names:Ccur92_11810
ORF Names:CCV52592_0308
OrganismiCampylobacter curvus (strain 525.92)
Taxonomic identifieri360105 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter
Proteomesi
  • UP000006380 Componenti: Chromosome

Subcellular locationi

A7GZ43:
  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000257631 – 54460 kDa chaperoninAdd BLAST544

Proteomic databases

PRIDEiA7GZ43.

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

Protein-protein interaction databases

STRINGi360105.CCV52592_0308.

Structurei

3D structure databases

ProteinModelPortaliA7GZ43.
SMRiA7GZ43.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CJ9. Bacteria.
COG0459. LUCA.
HOGENOMiHOG000076290.
KOiK04077.
OMAiTDTDKME.

Family and domain databases

CDDicd03344. GroEL. 1 hit.
Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPiMF_00600. CH60. 1 hit.
InterProiView protein in InterPro
IPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
PANTHERiPTHR11353. PTHR11353. 1 hit.
PfamiView protein in Pfam
PF00118. Cpn60_TCP1. 1 hit.
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF48592. SSF48592. 2 hits.
SSF52029. SSF52029. 1 hit.
TIGRFAMsiTIGR02348. GroEL. 1 hit.
PROSITEiView protein in PROSITE
PS00296. CHAPERONINS_CPN60. 1 hit.

Sequencei

Sequence statusi: Complete.

A7GZ43-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKEIFYSDD ARNRLYEGVR KLNDAVKVTM GPRGRNVLIQ KSFGAPSITK
60 70 80 90 100
DGVSVAKEVE LKDTIENMGA SLVREVASKT NDQAGDGTTT ATVLAHAIFK
110 120 130 140 150
EGLRNVTAGA NPIEVKRGMD KEVAALIDEL KNIAKKVSGS KEIAQIATIS
160 170 180 190 200
ANSDESIGKL IADAMEKVGK DGVITVEEAK SIEDELNVVE GMQFDRGYLS
210 220 230 240 250
PYFITNAEKM QVELSNPFIL LFDKKITNLK DLLPVLEQIQ KTGKPLLIVA
260 270 280 290 300
EDIEGEALAT LVVNKLRGVL NISAVKAPGF GDRRKAMLED IAILTGGEVI
310 320 330 340 350
SEELGRTLES ATLEDLGQAS SVVIDKDNTT IVNGAGEKSA IDARINQIKA
360 370 380 390 400
QIAETTSDYD KEKLQERLAK LSGGVAVIKV GAATETEMKE KKDRVDDALS
410 420 430 440 450
ATRAAVEEGI VVGGGSALIL ASKRVKLDLS GDEAIGAEIV RRALRAPLRQ
460 470 480 490 500
IAENAGFDAG VVTNAVEVSS DVNYGFNAVS GEYVNMFEAG IIDPVKVERV
510 520 530 540
ALQNAVSVAS LLLTTEATIS ELKEDKPMPA MPDMGGMGGM GGMM
Length:544
Mass (Da):57,923
Last modified:September 11, 2007 - v1
Checksum:i909CDC3ECE7B51BF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000767 Genomic DNA. Translation: EAU00075.2.
RefSeqiWP_009651280.1. NC_009715.2.

Genome annotation databases

EnsemblBacteriaiEAU00075; EAU00075; CCV52592_0308.
KEGGiccv:CCV52592_0308.

Similar proteinsi

Entry informationi

Entry nameiCH60_CAMC5
AccessioniPrimary (citable) accession number: A7GZ43
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: September 11, 2007
Last modified: October 25, 2017
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families