Reviewed, UniProtKB/Swiss-Prot A7GYC8 (ACKA_CAMC5)

Names and origin

Protein names

Recommended name:
    Acetate kinase
    EC=2.7.2.1
Alternative name(s):
    Acetokinase

Gene names

Name:	ackA
Ordered Locus Names:	Ccur92_09160
ORF Names:	CCV52592_1158

Organism

Campylobacter curvus (strain 525.92) [Complete proteome] [HAMAP]

Taxonomic identifier

360105 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter

Protein attributes

Sequence length	398 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020 ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the acetokinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	organic acid metabolic process Inferred from electronic annotation. Source: InterPro phosphorylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 398	398	Acetate kinase HAMAP MF_00020		PRO_1000002214

Sequences

	Sequence		Length	Mass (Da)
	A7GYC8-1 [UniParc]. Last modified September 11, 2007. Version 1. Checksum: 93422F90EB81278A	FASTA	398	44,381
	10 20 30 40 50 60 MKILVLNSGS SSIKFQLFLM EENRSIASGI VEQIGSENSR AVLKANSKEY EKKRAIKDHH 70 80 90 100 110 120 EGLDVMNELF RESNTLHDLS ELDGIGHRIV HGGESFFSSM IVDDSVIAKI EQISPLAPLH 130 140 150 160 170 180 NPGHIAGIKN AMQSSGDVPH VVVFDTVFHQ TMPEYAYRYA LPYDICKEHH IRKYGFHGTS 190 200 210 220 230 240 HRYVCKRAAS LMGMEFQNFN AISLHLGNGA SACAVQNGKS IDTSMGLSPL EGLIMGTRSG 250 260 270 280 290 300 DMDPAVVVYL LNIGVLKWDE IDTFLNKKSG LFGICGSSDM RDVVTRMAND ERAKLAFEMF 310 320 330 340 350 360 CYRVKKYIGA YYAVLGHVDA LIFTGGIGEN APNTRQKICD DLKHLGIHVN HDLNFSKERG 370 380 390 ERCLDDKNAK IKTFVIPTNE ELEIAIETMR VIKERAKI

References

[1]	"Genome sequence of Campylobacter curvus 525.92 isolated from human feces." Fouts D.E., Mongodin E.F., Puiu D., Sebastian Y., Miller W.G., Mandrell R.E., Lastovica A.J., Nelson K.E. Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000767 Genomic DNA. Translation: EAT99809.1.
RefSeq	YP_001408220.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A7GYC8.
Genome annotation databases
GeneID	5407688.
GenomeReviews	Gene locus Ccur92_09160 in contig CP000767_GR.
KEGG	ccv:CCV52592_1158.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	NGNERAT.
Family and domain databases
HAMAP	MF_00020. [Tree]
InterPro	IPR000890. Acetate/butyrate_kinase. IPR004372. AckA. [Graphical view]
PANTHER	PTHR21060. Acetate_kin. 1 hit. PTHR21060:SF11. AckA. 1 hit.
Pfam	PF00871. Acetate_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000722. Acetate_prop_kin. 1 hit.
PRINTS	PR00471. ACETATEKNASE.
TIGRFAMs	TIGR00016. ackA. 1 hit.
PROSITE	PS01075. ACETATE_KINASE_1. 1 hit. PS01076. ACETATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACKA_CAMC5

Accession

Primary (citable) accession number: A7GYC8

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	September 11, 2007
Last modified:	November 3, 2009
This is version 15 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)