Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

A7GYC3

- A7GYC3_CAMC5

UniProt

A7GYC3 - A7GYC3_CAMC5

Protein
Submitted name:

D-alanine--D-alanine ligase (D-alanylalanine synthetase)(D-Ala-D-Ala ligase)

Gene

CCV52592_1152

Organism
Campylobacter curvus (strain 525.92)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 55 (01 Oct 2014)
      Sequence version 1 (11 Sep 2007)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Cell wall formation.SAAS annotation

    Catalytic activityi

    ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine.SAAS annotation

    Cofactori

    Binds 2 magnesium or manganese ions per subunit.SAAS annotation

    Pathwayi

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. D-alanine-D-alanine ligase activity Source: UniProtKB-EC
    3. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. peptidoglycan biosynthetic process Source: UniProtKB-UniPathway
    2. regulation of cell shape Source: UniProtKB-KW

    Keywords - Molecular functioni

    LigaseSAAS annotationImported

    Keywords - Biological processi

    Cell shape, Cell wall biogenesis/degradationSAAS annotation, Peptidoglycan synthesisSAAS annotation

    Keywords - Ligandi

    ATP-bindingSAAS annotation, MagnesiumSAAS annotation, ManganeseSAAS annotation, Metal-bindingSAAS annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciCCUR360105:GJ9P-995-MONOMER.
    UniPathwayiUPA00219.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    D-alanine--D-alanine ligase (D-alanylalanine synthetase)(D-Ala-D-Ala ligase)Imported (EC:6.3.2.4Imported)
    Gene namesi
    ORF Names:CCV52592_1152Imported
    OrganismiCampylobacter curvus (strain 525.92)Imported
    Taxonomic identifieri360105 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter
    ProteomesiUP000006380: Chromosome

    Subcellular locationi

    Cytoplasm SAAS annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmSAAS annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi360105.CCV52592_1152.

    Structurei

    3D structure databases

    ProteinModelPortaliA7GYC3.
    SMRiA7GYC3. Positions 1-318.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains ATP-grasp domain.SAAS annotation

    Phylogenomic databases

    eggNOGiCOG1181.
    HOGENOMiHOG000102494.
    KOiK01921.
    OMAiHNGLLKN.
    OrthoDBiEOG6ND0KB.

    Family and domain databases

    Gene3Di3.30.1490.20. 1 hit.
    3.30.470.20. 1 hit.
    3.40.50.20. 1 hit.
    InterProiIPR011761. ATP-grasp.
    IPR013815. ATP_grasp_subdomain_1.
    IPR013816. ATP_grasp_subdomain_2.
    IPR000291. D-Ala_lig_Van_CS.
    IPR005905. D_ala_D_ala.
    IPR011095. Dala_Dala_lig_C.
    IPR011127. Dala_Dala_lig_N.
    IPR016185. PreATP-grasp_dom.
    [Graphical view]
    PANTHERiPTHR23132. PTHR23132. 1 hit.
    PfamiPF07478. Dala_Dala_lig_C. 1 hit.
    PF01820. Dala_Dala_lig_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF52440. SSF52440. 1 hit.
    TIGRFAMsiTIGR01205. D_ala_D_alaTIGR. 1 hit.
    PROSITEiPS50975. ATP_GRASP. 1 hit.
    PS00843. DALA_DALA_LIGASE_1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A7GYC3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKLGVVFGAK SFEHEISIVS AIVLKNVLKQ ELSFIFCDKE RKFYLIEPTD    50
    MRANFFSSGK YKKCKKLFLM ACGFYTHSLF GVKRLEVDVY INLIHGMDGE 100
    DGKFASLFDF YGISYIGPRL EASVMSYNKE LTKFLAQKVG VKTLDYEMIT 150
    YEELPKFALP IILKPARLGS SIGVSVVKDE SEFEYARDVA FEFDKEVLVE 200
    PFIEGVKEYN LAGCMIDGKM RFSIVEEPKK KEFLDYEQKY MSFSNESKAQ 250
    EARIDEELRD RLKENFVKIY GFGFEGAIIR CDFFVIEGEV YLNEINPNPG 300
    SLANYLFEDF EAMLNALAAS RLPKERKINI DYKFINSITS AKGSGKI 347
    Length:347
    Mass (Da):39,781
    Last modified:September 11, 2007 - v1
    Checksum:iF26A795969764B80
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000767 Genomic DNA. Translation: EAT99804.1.
    RefSeqiYP_001408215.1. NC_009715.1.

    Genome annotation databases

    EnsemblBacteriaiEAT99804; EAT99804; CCV52592_1152.
    GeneIDi5406834.
    KEGGiccv:CCV52592_1152.
    PATRICi20032300. VBICamCur47627_0959.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000767 Genomic DNA. Translation: EAT99804.1 .
    RefSeqi YP_001408215.1. NC_009715.1.

    3D structure databases

    ProteinModelPortali A7GYC3.
    SMRi A7GYC3. Positions 1-318.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 360105.CCV52592_1152.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai EAT99804 ; EAT99804 ; CCV52592_1152 .
    GeneIDi 5406834.
    KEGGi ccv:CCV52592_1152.
    PATRICi 20032300. VBICamCur47627_0959.

    Phylogenomic databases

    eggNOGi COG1181.
    HOGENOMi HOG000102494.
    KOi K01921.
    OMAi HNGLLKN.
    OrthoDBi EOG6ND0KB.

    Enzyme and pathway databases

    UniPathwayi UPA00219 .
    BioCyci CCUR360105:GJ9P-995-MONOMER.

    Family and domain databases

    Gene3Di 3.30.1490.20. 1 hit.
    3.30.470.20. 1 hit.
    3.40.50.20. 1 hit.
    InterProi IPR011761. ATP-grasp.
    IPR013815. ATP_grasp_subdomain_1.
    IPR013816. ATP_grasp_subdomain_2.
    IPR000291. D-Ala_lig_Van_CS.
    IPR005905. D_ala_D_ala.
    IPR011095. Dala_Dala_lig_C.
    IPR011127. Dala_Dala_lig_N.
    IPR016185. PreATP-grasp_dom.
    [Graphical view ]
    PANTHERi PTHR23132. PTHR23132. 1 hit.
    Pfami PF07478. Dala_Dala_lig_C. 1 hit.
    PF01820. Dala_Dala_lig_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52440. SSF52440. 1 hit.
    TIGRFAMsi TIGR01205. D_ala_D_alaTIGR. 1 hit.
    PROSITEi PS50975. ATP_GRASP. 1 hit.
    PS00843. DALA_DALA_LIGASE_1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of Campylobacter curvus 525.92 isolated from human feces."
      Fouts D.E., Mongodin E.F., Puiu D., Sebastian Y., Miller W.G., Mandrell R.E., Lastovica A.J., Nelson K.E.
      Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 525.92Imported.

    Entry informationi

    Entry nameiA7GYC3_CAMC5
    AccessioniPrimary (citable) accession number: A7GYC3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 11, 2007
    Last sequence update: September 11, 2007
    Last modified: October 1, 2014
    This is version 55 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3