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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Campylobacter curvus (strain 525.92)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:Ccur92_03630
ORF Names:CCV52592_1254
OrganismiCampylobacter curvus (strain 525.92)
Taxonomic identifieri360105 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter
Proteomesi
  • UP000006380 Componenti: Chromosome

Subcellular locationi

A7GWS5:
  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000180081 – 529Arginine--tRNA ligaseAdd BLAST529

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi360105.CCV52592_1254.

Structurei

3D structure databases

ProteinModelPortaliA7GWS5.
SMRiA7GWS5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi113 – 123"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75. Bacteria.
COG0018. LUCA.
HOGENOMiHOG000247214.
KOiK01887.
OMAiNKPLHLG.

Family and domain databases

CDDicd00671. ArgRS_core. 1 hit.
Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR036695. Arg-tRNA-synth_N_sf.
IPR035684. ArgRS_core.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

A7GWS5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKEIIKSEIF KILGRDFVLE KPKDKSLAHY ATPLAFSLAK ELKKSPVAIA
60 70 80 90 100
NELACKFENS KIFEVSAVNG YLNFKLKGEF LDEISKDALK NGDKFASGKA
110 120 130 140 150
RQDGSTFIEY ISANPTGPLH IGHVRGAVYG DTLARIGTHL GYKIFTEYYI
160 170 180 190 200
NDAGNQIDLL GTSISLAARD VLFHENVEYP QKYYRGEYIV DIANEALKKF
210 220 230 240 250
GKEIFYDEAR NLELAEFGKD IVLDIIKKDL AGVGISIQGW ASEKALYKEL
260 270 280 290 300
EPTIEKLKRS NQMYEKEGAT YIASTTLGDD NDRVVVRNDG RPTYLAGDII
310 320 330 340 350
YHNDKFERNY DHYINIWGAD HHGYIARLKA AIHFLGYDEN RLEIILMQMV
360 370 380 390 400
SLLKDGKPYK MSKRAGNAVL MSDIVEEIGS DALRFIFISK ANTSSLEFDI
410 420 430 440 450
DELKKEDSSN PIFYINYAHA RVNQIFAKAG KSVSDVLDAS LENLDDNAKN
460 470 480 490 500
LLFEALILPE ILEDAFASRQ LQKVSDYLKS LAASFHKFYN ENRVIGSANE
510 520
ESLLKLFAVV ALSLRTALSL IGITAKDRM
Length:529
Mass (Da):59,465
Last modified:September 11, 2007 - v1
Checksum:i6B83E561B698F440
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000767 Genomic DNA. Translation: EAU00901.1.
RefSeqiWP_011991873.1. NC_009715.2.

Genome annotation databases

EnsemblBacteriaiEAU00901; EAU00901; CCV52592_1254.
KEGGiccv:CCV52592_1254.

Similar proteinsi

Entry informationi

Entry nameiSYR_CAMC5
AccessioniPrimary (citable) accession number: A7GWS5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: September 11, 2007
Last modified: October 25, 2017
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families