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A7GSF3 (A7GSF3_BACCN) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Arginine biosynthesis bifunctional protein ArgJ HAMAP MF_01106
Gene names
Name:argJ HAMAP MF_01106
Ordered Locus Names:Bcer98_2828
OrganismBacillus cereus subsp. cytotoxis (strain NVH 391-98) [Complete proteome] [HAMAP] EMBL ABS23061.1
Taxonomic identifier315749 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length407 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate By similarity. HAMAP MF_01106

Catalytic activity

Acetyl-CoA + L-glutamate = CoA + N-acetyl-L-glutamate. HAMAP MF_01106

N(2)-acetyl-L-ornithine + L-glutamate = L-ornithine + N-acetyl-L-glutamate. HAMAP MF_01106

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; L-ornithine and N-acetyl-L-glutamate from L-glutamate and N(2)-acetyl-L-ornithine (cyclic): step 1/1. HAMAP MF_01106

Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 1/4. HAMAP MF_01106

Subunit structure

Heterotetramer of two alpha and two beta chains By similarity. HAMAP MF_01106

Subcellular location

Cytoplasm By similarity HAMAP MF_01106.

Miscellaneous

Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway By similarity. HAMAP MF_01106

Sequence similarities

Belongs to the ArgJ family. HAMAP MF_01106

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Site193 – 1942Cleavage; by autolysis By similarity HAMAP MF_01106

Sequences

Sequence LengthMass (Da)Tools
A7GSF3 [UniParc].

Last modified September 11, 2007. Version 1.
Checksum: 410BEB4D7EC41C7F

FASTA40744,191
        10         20         30         40         50         60 
MIQTDCLIKV QNGSIVSPQG FSAIGIKAGL KKEKKDLGVI VCDVPAICAA VYTTNQIQAA 

        70         80         90        100        110        120 
PVQVTKESIG VDGTLQVIIV NSGNANACTG MKGLEDAYEM RALTAKQFSI KESDVAVAST 

       130        140        150        160        170        180 
GVIGIHLPME VIRTGISALV PMKEKEIAES FYEAILTTDL IEKRSSYQFM IEGKKVTISG 

       190        200        210        220        230        240 
AAKGSGMIHP NMATMLSFIT TDAKIERESL QAALSEVTNR TFNQITVDGD TSTNDMVIVM 

       250        260        270        280        290        300 
ASGLVETTSI HKNHPEWNKF VIALQNVCED LAKQIAKDGE GATKLVEVNV CGARTEEEGR 

       310        320        330        340        350        360 
QIAKQIVRSS LVKTAMYGED PNWGRIISAI GQCGIKIEPT TVDIAVQSIA VLRESEPQEF 

       370        380        390        400 
SEEEMEHQLQ KDEIIIDVHL HLGEEKGTAW GCDLSYDYVK INACYRT

« Hide

References

[1]"Extending the Bacillus cereus group genomics to putative food-borne pathogens of different toxicity."
Lapidus A., Goltsman E., Auger S., Galleron N., Segurens B., Dossat C., Land M.L., Broussolle V., Brillard J., Guinebretiere M.-H., Sanchis V., Nguen-the C., Lereclus D., Richardson P., Wincker P., Weissenbach J., Ehrlich S.D., Sorokin A.
Chem. Biol. Interact. 171:236-249(2008) [PubMed: 17434157] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000764 Genomic DNA. Translation: ABS23061.1.
RefSeqYP_001376056.1. NC_009674.1.

3D structure databases

ProteinModelPortalA7GSF3.
SMRA7GSF3. Positions 5-405.
ModBaseSearch...

Protein-protein interaction databases

STRINGA7GSF3.

Protein family/group databases

MEROPST05.001.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBACT00000039062; EBBACP00000038113; EBBACG00000039053.
GeneID5343639.
GenomeReviewsGene locus Bcer98_2828 in contig CP000764_GR.
KEGGbcy:Bcer98_2828.
PATRIC18934270. VBIBacCyt128034_2979.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1364.
GeneTreeEBGT00050000002382.
HOGENOMHBG284202.
OMAGRDPNWG.
ProtClustDBPRK05388.

Family and domain databases

HAMAPMF_01106. ArgJ.
[Tree]
InterProIPR002813. Arg_biosynth_ArgJ.
IPR016117. Pept_S58_DmpA/Arg_biosyn_ArgJ.
[Graphical view]
KOK00620.
PANTHERPTHR23100. ArgJ. 1 hit.
PfamPF01960. ArgJ. 1 hit.
[Graphical view]
ProDomPD004193. Arg_biosynth_ArgJ. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMSSF56266. Pept_S58_DmpA/Arg_biosyn_ArgJ. 1 hit.
TIGRFAMsTIGR00120. ArgJ. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA7GSF3_BACCN
AccessionPrimary (citable) accession number: A7GSF3
Entry history
Integrated into UniProtKB/TrEMBL: September 11, 2007
Last sequence update: September 11, 2007
Last modified: December 14, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info