A7GQI9 (MQO_BACCN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable malate:quinone oxidoreductase
EC=1.1.5.4

Alternative name(s):
MQO
Malate dehydrogenase [quinone]

Gene names

Name:	mqo
Ordered Locus Names:	Bcer98_2135

Organism

Bacillus cereus subsp. cytotoxis (strain NVH 391-98) [Complete proteome] [HAMAP]

Taxonomic identifier

315749 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length	500 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(S)-malate + a quinone = oxaloacetate + reduced quinone. HAMAP MF_00212
Cofactor	FAD By similarity. HAMAP MF_00212
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle; oxaloacetate from (S)-malate (quinone route): step 1/1. HAMAP MF_00212
Sequence similarities	Belongs to the MQO family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tricarboxylic acid cycle Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	malate dehydrogenase (menaquinone) activity Inferred from electronic annotation. Source: EC malate dehydrogenase (quinone) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 500	500	Probable malate:quinone oxidoreductase HAMAP MF_00212		PRO_1000078030

Sequences

	Sequence		Length	Mass (Da)
	A7GQI9 [UniParc]. Last modified September 11, 2007. Version 1. Checksum: 91AC53999FA9FABD	FASTA	500	55,525
	10 20 30 40 50 60 MSNMQKKTDV ILIGAGIMSA TLGSLLKELA PEWEIKMFEK LEGAGEESSN EWNNAGTGHS 70 80 90 100 110 120 ALCELNYTSE KPDGSIDIKK ALKINEQFQL SRQFWSYLVN SNLIRNPQKF IMPIPHMSLV 130 140 150 160 170 180 QGEKNVTFLK KRFKALSNIP LFQGMEFSDD PEKLKEWMPL IMEGRTSNEP IAATKMESGT 190 200 210 220 230 240 DVNFGALTRM LFEHLQNKNV ELNYKHSVEN IKRMKNGLWE VKVHDMNNGK IEYHTAKFVF 250 260 270 280 290 300 IGAGGGSLPL LQKTGIPESK HIGGFPVSGL FMVCNNPKVI EKHHAKVYGK AKVGAPPMSV 310 320 330 340 350 360 PHLDTRYIDN KKTLLFGPFA GFSPKFLKTG SNLDLLGSVK PNNVLTMLAA GVKEMALTKY 370 380 390 400 410 420 LIQQVMLSNE KRIEELREFI PNAKGEDWDV VVAGQRVQVI KDTETGGKGT LQFGTEVVSA 430 440 450 460 470 480 ADGSIAALLG ASPGASTAVN VMLEVLEKCF PQYMEKWEEK IKHMIPSYGI SLVENPKLFQ 490 500 EIHTSTSKTL GLSKKEAVYS

References

[1]

"Extending the Bacillus cereus group genomics to putative food-borne pathogens of different toxicity." Lapidus A., Goltsman E., Auger S., Galleron N., Segurens B., Dossat C., Land M.L., Broussolle V., Brillard J., Guinebretiere M.-H., Sanchis V., Nguen-the C., Lereclus D., Richardson P., Wincker P., Weissenbach J., Ehrlich S.D., Sorokin A. Chem. Biol. Interact. 171:236-249(2008) [PubMed: 17434157] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NVH 391-98.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000764 Genomic DNA. Translation: ABS22397.1.
RefSeq	YP_001375392.1. NC_009674.1.
3D structure databases
ProteinModelPortal	A7GQI9.
ModBase	Search...
Protein-protein interaction databases
STRING	A7GQI9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000039051; EBBACP00000038102; EBBACG00000039042.
GeneID	5346954.
GenomeReviews	Gene locus Bcer98_2135 in contig CP000764_GR.
KEGG	bcy:Bcer98_2135.
PATRIC	18932838. VBIBacCyt128034_2263.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0579.
GeneTree	EBGT00050000004051.
HOGENOM	HBG289663.
OMA	REMIPSY.
ProtClustDB	PRK05257.
Enzyme and pathway databases
BioCyc	BCER315749:BCER98_2135-MONOMER.
Family and domain databases
HAMAP	MF_00212. MQO. [Tree]
InterPro	IPR006231. Malate_quinone_OxRdtase. [Graphical view]
KO	K00116.
PANTHER	PTHR13847:SF14. PTHR13847:SF14. 1 hit.
Pfam	PF06039. Mqo. 1 hit. [Graphical view]
TIGRFAMs	TIGR01320. Mal_quin_oxido. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MQO_BACCN

Accession

Primary (citable) accession number: A7GQI9

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	September 11, 2007
Last modified:	December 14, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program