A7GNQ4 (A7GNQ4_BACCN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrA HAMAP MF_01401
Short name=Protein-methionine-S-oxide reductase HAMAP MF_01401
EC=1.8.4.11 HAMAP MF_01401

Alternative name(s):
Peptide-methionine (S)-S-oxide reductase HAMAP MF_01401

Gene names

Name:	msrA HAMAP MF_01401
Ordered Locus Names:	Bcer98_1443

Organism

Bacillus cereus subsp. cytotoxis (strain NVH 391-98) [Complete proteome] [HAMAP] EMBL ABS21762.1

Taxonomic identifier

315749 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length	178 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP MF_01401
Catalytic activity	L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401
Sequence similarities	Belongs to the MsrA Met sulfoxide reductase family. HAMAP MF_01401

Ontologies

Keywords
Molecular function	Oxidoreductase HAMAP MF_01401 EMBL ABS21762.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	protein modification process Inferred from electronic annotation. Source: HAMAP
Molecular function	peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	15	1	By similarity HAMAP MF_01401

Sequences

	Sequence		Length	Mass (Da)
	A7GNQ4 [UniParc]. Last modified September 11, 2007. Version 1. Checksum: 394F968812DF6A18	FASTA	178	20,556
	10 20 30 40 50 60 MSKKTFELAT FAGGCFWCMV KPFDELPGIQ KVVSGYTGGH ISNPTYEQVK SGTSGHLEVV 70 80 90 100 110 120 QMTFDPSIFP YQKLLDLYWS QIDPTDDGGQ FFDRGPSYRT AIFYHNETQK ELAEKSKQLL 130 140 150 160 170 ATSGIFNEPI VTEIRPAAPF YEAEEYHQHF YKKNPKKYAQ ERKESGREDF IKTNWQKK

References

[1]

"Extending the Bacillus cereus group genomics to putative food-borne pathogens of different toxicity." Lapidus A., Goltsman E., Auger S., Galleron N., Segurens B., Dossat C., Land M.L., Broussolle V., Brillard J., Guinebretiere M.-H., Sanchis V., Nguen-the C., Lereclus D., Richardson P., Wincker P., Weissenbach J., Ehrlich S.D., Sorokin A. Chem. Biol. Interact. 171:236-249(2008) [PubMed: 17434157] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000764 Genomic DNA. Translation: ABS21762.1.
RefSeq	YP_001374757.1. NC_009674.1.
3D structure databases
ProteinModelPortal	A7GNQ4.
ModBase	Search...
Protein-protein interaction databases
STRING	A7GNQ4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000038945; EBBACP00000037996; EBBACG00000038936.
GeneID	5344028.
GenomeReviews	Gene locus Bcer98_1443 in contig CP000764_GR.
KEGG	bcy:Bcer98_1443.
PATRIC	18931348. VBIBacCyt128034_1518.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0225.
GeneTree	EBGT00050000000580.
HOGENOM	HBG748152.
OMA	ISGRDEF.
ProtClustDB	CLSK916383.
Family and domain databases
HAMAP	MF_01401. MsrA. [Tree]
InterPro	IPR002569. Peptide_Met_Sox_Rdtase_MsrA. [Graphical view]
Gene3D	G3DSA:3.30.1060.10. MsrA. 1 hit.
KO	K07304.
Pfam	PF01625. PMSR. 1 hit. [Graphical view]
SUPFAM	SSF55068. MsrA. 1 hit.
TIGRFAMs	TIGR00401. MsrA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A7GNQ4_BACCN

Accession

Primary (citable) accession number: A7GNQ4

Entry history

Integrated into UniProtKB/TrEMBL:	September 11, 2007
Last sequence update:	September 11, 2007
Last modified:	December 14, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)