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Protein

Sulfate adenylyltransferase

Gene

sat

Organism
Bacillus cytotoxicus (strain DSM 22905 / CIP 110041 / 391-98 / NVH 391-98)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + sulfate = diphosphate + adenylyl sulfate.UniRule annotation

Pathwayi: hydrogen sulfide biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes sulfite from sulfate.UniRule annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. Sulfate adenylyltransferase (sat)
  2. Adenylyl-sulfate kinase (cysC)
  3. Phosphoadenosine phosphosulfate reductase (cysH)
This subpathway is part of the pathway hydrogen sulfide biosynthesis, which is itself part of Sulfur metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes sulfite from sulfate, the pathway hydrogen sulfide biosynthesis and in Sulfur metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionNucleotidyltransferase, Transferase
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00140; UER00204.

Names & Taxonomyi

Protein namesi
Recommended name:
Sulfate adenylyltransferaseUniRule annotation (EC:2.7.7.4UniRule annotation)
Alternative name(s):
ATP-sulfurylaseUniRule annotation
Sulfate adenylate transferaseUniRule annotation
Short name:
SATUniRule annotation
Gene namesi
Name:satUniRule annotation
Ordered Locus Names:Bcer98_1144
OrganismiBacillus cytotoxicus (strain DSM 22905 / CIP 110041 / 391-98 / NVH 391-98)
Taxonomic identifieri315749 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
Proteomesi
  • UP000002300 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003406121 – 375Sulfate adenylyltransferaseAdd BLAST375

Interactioni

Protein-protein interaction databases

STRINGi315749.Bcer98_1144.

Structurei

3D structure databases

ProteinModelPortaliA7GMW1.
SMRiA7GMW1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the sulfate adenylyltransferase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107RIQ. Bacteria.
COG2046. LUCA.
HOGENOMiHOG000069044.
KOiK00958.
OMAiRMRCYEI.
OrthoDBiPOG091H0GMI.

Family and domain databases

CDDicd00517. ATPS. 1 hit.
Gene3Di3.40.50.620. 1 hit.
HAMAPiMF_00066. Sulf_adenylyltr. 1 hit.
InterProiView protein in InterPro
IPR025980. ATP-Sase_PUA-like_dom.
IPR015947. PUA-like_sf.
IPR014729. Rossmann-like_a/b/a_fold.
IPR020792. SO4_adenylyltransferase_pro.
IPR024951. Sulfurylase_cat_dom.
IPR002650. Sulphate_adenylyltransferase.
PfamiView protein in Pfam
PF01747. ATP-sulfurylase. 1 hit.
PF14306. PUA_2. 1 hit.
SUPFAMiSSF88697. SSF88697. 1 hit.
TIGRFAMsiTIGR00339. sopT. 1 hit.

Sequencei

Sequence statusi: Complete.

A7GMW1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTATNFLVNR IDETYDTANI VQEIELDSIA LSDLELLATG GYSPLIGFLG
60 70 80 90 100
EEEYQSVVET MRLTDGSIWS IPITLPVTEE KAEQLQVGEE ALLVKDGVTY
110 120 130 140 150
GVIQIEDIFT PNKEKEALFV YKTTEDAHPG VKKLYERANV YVGGAITIVK
160 170 180 190 200
RVEHKKFASY YLDPSETREI FEKRGWKTVV GFQTRNPVHR AHEYIQKSAL
210 220 230 240 250
EIVDGLFLNP LVGETKSDDI PADVRMESYE VLLKHYYPND RVFLGVFPAA
260 270 280 290 300
MRYAGPREAI FHALVRRNFG CTHFIVGRDH AGVGNYYGTY EAQEIFKLFT
310 320 330 340 350
VEELGITPLF FEHSFYCKKC EAMASTKTCP HGKEDHVILS GTKVREMLRD
360 370
GDVPPSTFSR KEVIEVLIRG LQKAR
Length:375
Mass (Da):42,493
Last modified:September 11, 2007 - v1
Checksum:i35B9A20F50A6CAEE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000764 Genomic DNA. Translation: ABS21469.1.
RefSeqiWP_011984222.1. NC_009674.1.

Genome annotation databases

EnsemblBacteriaiABS21469; ABS21469; Bcer98_1144.
GeneIDi33896498.
KEGGibcy:Bcer98_1144.

Similar proteinsi

Entry informationi

Entry nameiSAT_BACCN
AccessioniPrimary (citable) accession number: A7GMW1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: September 11, 2007
Last modified: November 22, 2017
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome