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A7GKX3 (GLSA_BACCN) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutaminase

EC=3.5.1.2
Gene names
Name:glsA
Ordered Locus Names:Bcer98_0426
OrganismBacillus cereus subsp. cytotoxis (strain NVH 391-98) [Complete proteome] [HAMAP]
Taxonomic identifier315749 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group

Protein attributes

Sequence length309 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-glutamine + H2O = L-glutamate + NH3. HAMAP-Rule MF_00313

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00313

Sequence similarities

Belongs to the glutaminase family.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglutamine metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionglutaminase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 309309Glutaminase HAMAP-Rule MF_00313
PRO_1000079070

Sites

Binding site651Substrate By similarity
Binding site1171Substrate By similarity
Binding site1621Substrate By similarity
Binding site1691Substrate By similarity
Binding site1931Substrate By similarity
Binding site2451Substrate By similarity
Binding site2631Substrate; via amide nitrogen By similarity

Sequences

Sequence LengthMass (Da)Tools
A7GKX3 [UniParc].

Last modified September 11, 2007. Version 1.
Checksum: 170E118B08ADB01B

FASTA30934,074
        10         20         30         40         50         60 
MQCVETNNLK QLLEQVKPYT KKGKLATYIP ELGNANPDDL GIAIYHKETE YVHAGSSQML 

        70         80         90        100        110        120 
FTLQSISKVI TLALALLDRG EEYVFSKVGM EPTGDPFNSI IKLETTSPSK PLNPMINAGA 

       130        140        150        160        170        180 
LAITSMLKGA NNEEKIERIL NFVREITDNP TIHYSAKVAT SELETAYLNR SLCYYMKQNG 

       190        200        210        220        230        240 
IIDNDIEELM DLYTRQCAIE VNCIDLARIG LIFAMDGYDP YKQKQIIPKH ITKICKTFMV 

       250        260        270        280        290        300 
TCGMYNESGE FAIRVGIPAK SGVAGGIFGC VKGEMGIGIF GPALDENGNS IAGFKILELL 


SAQEGWSIF 

« Hide

References

[1]"Extending the Bacillus cereus group genomics to putative food-borne pathogens of different toxicity."
Lapidus A., Goltsman E., Auger S., Galleron N., Segurens B., Dossat C., Land M.L., Broussolle V., Brillard J., Guinebretiere M.-H., Sanchis V., Nguen-the C., Lereclus D., Richardson P., Wincker P., Weissenbach J., Ehrlich S.D., Sorokin A.
Chem. Biol. Interact. 171:236-249(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: NVH 391-98.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000764 Genomic DNA. Translation: ABS20781.1.
RefSeqYP_001373776.1. NC_009674.1.

3D structure databases

ProteinModelPortalA7GKX3.
SMRA7GKX3. Positions 7-309.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING315749.Bcer98_0426.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABS20781; ABS20781; Bcer98_0426.
GeneID5344798.
KEGGbcy:Bcer98_0426.
PATRIC18929136. VBIBacCyt128034_0456.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2066.
HOGENOMHOG000216890.
KOK01425.
OMARINALML.
OrthoDBEOG6N94BK.
ProtClustDBPRK00971.

Enzyme and pathway databases

BioCycBCYT315749:GH2A-496-MONOMER.

Family and domain databases

Gene3D3.40.710.10. 1 hit.
HAMAPMF_00313. Glutaminase.
InterProIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERPTHR12544. PTHR12544. 1 hit.
PfamPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMSSF56601. SSF56601. 1 hit.
TIGRFAMsTIGR03814. Gln_ase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLSA_BACCN
AccessionPrimary (citable) accession number: A7GKX3
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: September 11, 2007
Last modified: February 19, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families