Reviewed, UniProtKB/Swiss-Prot A7GJE7 (COMB_CLOBL)

Names and origin

Protein names

Recommended name:
    Probable 2-phosphosulfolactate phosphatase
    EC=3.1.3.71

Gene names

Name:	comB
Ordered Locus Names:	CLI_3775

Organism

Clostridium botulinum (strain Langeland / NCTC 10281 / Type F) [Complete proteome] [HAMAP]

Taxonomic identifier

441772 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length	239 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	(2R)-2-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate. HAMAP MF_00490
Cofactor	Magnesium By similarity.
Sequence similarities	Belongs to the comB family.

Ontologies

Keywords
Ligand	Magnesium
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	coenzyme M biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	2-phosphosulfolactate phosphatase activity Inferred from electronic annotation. Source: HAMAP magnesium ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 239	239	Probable 2-phosphosulfolactate phosphatase HAMAP MF_00490		PRO_1000014461

Sequences

	Sequence		Length	Mass (Da)
	A7GJE7-1 [UniParc]. Last modified September 11, 2007. Version 1. Checksum: 2274CB3A93F12B81	FASTA	239	26,747
	10 20 30 40 50 60 MNIDIVISAD HIDEKRLINK TVIIIDILRA TSVITTAINN GCKKVIPVLT VEEAKDIAKN 70 80 90 100 110 120 SKEDIILGGE RNALKIDGFN FSNSPLEYTK KYVEGKTVVL STTNGTRAIN NSFNAKTILI 130 140 150 160 170 180 SALINSKATA KAIDKLNEEL IIINSGTNGQ FSIDDFICSG YLIDCLYNIR KDLELSDIAK 190 200 210 220 230 TAHYIYTNNK DIESFVKKAT HYSRLKSLNL EKDLEYCFQK DIIDVVPQYK DGYIIKSNI

References

[1]	Brinkac L.M., Daugherty S., Dodson R.J., Madupu R., Brown J.L., Bruce D., Detter C., Munk C., Smith L.A., Smith T.J., White O., Brettin T.S. Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000728 Genomic DNA. Translation: ABS40689.1.
RefSeq	YP_001392907.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	5403642.
GenomeReviews	Gene locus CLI_3775 in contig CP000728_GR.
KEGG	cbf:CLI_3775.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	A7GJE7. DFICSGY.
Family and domain databases
HAMAP	MF_00490. [Tree]
InterPro	IPR005238. 2-PSlactate_phosphatase. [Graphical view]
Gene3D	G3DSA:3.90.1560.10. 2-PSlactate_phosphatase. 1 hit.
Pfam	PF04029. 2-ph_phosp. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

COMB_CLOBL

Accession

Primary (citable) accession number: A7GJE7

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	September 11, 2007
Last modified:	June 16, 2009
This is version 9 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)