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Protein

Elongation factor Tu

Gene

tuf1

more
Organism
Clostridium botulinum (strain Langeland / NCTC 10281 / Type F)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi19 – 26GTPUniRule annotation8
Nucleotide bindingi81 – 85GTPUniRule annotation5
Nucleotide bindingi136 – 139GTPUniRule annotation4

GO - Molecular functioni

Keywordsi

Molecular functionElongation factor
Biological processProtein biosynthesis
LigandGTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Short name:
EF-TuUniRule annotation
Gene namesi
Name:tuf1UniRule annotation
Ordered Locus Names:CLI_3665
AND
Name:tuf2UniRule annotation
Ordered Locus Names:CLI_3679
OrganismiClostridium botulinum (strain Langeland / NCTC 10281 / Type F)
Taxonomic identifieri441772 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
Proteomesi
  • UP000002410 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003373581 – 397Elongation factor TuAdd BLAST397

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliA7GJ76
SMRiA7GJ76
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 206tr-type GAdd BLAST197

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni19 – 26G1By similarity8
Regioni60 – 64G2By similarity5
Regioni81 – 84G3By similarity4
Regioni136 – 139G4By similarity4
Regioni174 – 176G5By similarity3

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000229290
KOiK02358
OMAiAIRDMGM

Family and domain databases

CDDicd03697 EFTU_II, 1 hit
HAMAPiMF_00118_B EF_Tu_B, 1 hit
InterProiView protein in InterPro
IPR004161 EFTu-like_2
IPR033720 EFTU_2
IPR031157 G_TR_CS
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR000795 TF_GTP-bd_dom
IPR009000 Transl_B-barrel_sf
IPR009001 Transl_elong_EF1A/Init_IF2_C
IPR004541 Transl_elong_EFTu/EF1A_bac/org
IPR004160 Transl_elong_EFTu/EF1A_C
PfamiView protein in Pfam
PF00009 GTP_EFTU, 1 hit
PF03144 GTP_EFTU_D2, 1 hit
PF03143 GTP_EFTU_D3, 1 hit
PRINTSiPR00315 ELONGATNFCT
SUPFAMiSSF50447 SSF50447, 1 hit
SSF50465 SSF50465, 1 hit
SSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00485 EF-Tu, 1 hit
TIGR00231 small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS00301 G_TR_1, 1 hit
PS51722 G_TR_2, 1 hit

Sequencei

Sequence statusi: Complete.

A7GJ76-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKAKFERSK PHVNIGTIGH VDHGKTTLTA AITTVLAQKG GASATKYDEI
60 70 80 90 100
DKAPEEKERG ITINTSHVEY ETANRHYAHV DCPGHADYVK NMITGAAQMD
110 120 130 140 150
GAILVVSAAD GPMPQTREHI LLASRVGVQY IVVFLNKADQ VDDPELIELV
160 170 180 190 200
EMEVRELLNE YGFPGDDTPI VVGSALEVLE NQDNAEKTKC IDELMEAIDS
210 220 230 240 250
YIPTPERATD QPFLMPVEDV FTITGRGTVA TGRVERGVLH TGDEVELIGM
260 270 280 290 300
KQEVSKTVCT GIEMFRKILD EAMAGDNIGA LLRGIQRDEI QRGQVLAKPG
310 320 330 340 350
SVTPHKKFVG QVYVLKKEEG GRHTPFFNGY RPQFYFRTTD VTGSINLPEG
360 370 380 390
VEMVMPGDHI DMAVELITPV AMHENLRFAI REGGRTVGSG VVTTISE
Length:397
Mass (Da):43,483
Last modified:September 11, 2007 - v1
Checksum:i75AD3C5B65D90FA8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000728 Genomic DNA Translation: ABS40668.1
CP000728 Genomic DNA Translation: ABS42648.1
RefSeqiWP_003357263.1, NC_009699.1

Genome annotation databases

EnsemblBacteriaiABS40668; ABS40668; CLI_3665
ABS42648; ABS42648; CLI_3679
KEGGicbf:CLI_3665
cbf:CLI_3679

Similar proteinsi

Entry informationi

Entry nameiEFTU_CLOBL
AccessioniPrimary (citable) accession number: A7GJ76
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: September 11, 2007
Last modified: November 22, 2017
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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