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A7GIL4

- G6PI_CLOBL

UniProt

A7GIL4 - G6PI_CLOBL

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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Clostridium botulinum (strain Langeland / NCTC 10281 / Type F)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei291 – 2911Proton donorUniRule annotation
Active sitei312 – 3121UniRule annotation
Active sitei426 – 4261UniRule annotation

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciCBOT441772:GJIE-3414-MONOMER.
UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:CLI_3449
OrganismiClostridium botulinum (strain Langeland / NCTC 10281 / Type F)
Taxonomic identifieri441772 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
ProteomesiUP000002410: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 450450Glucose-6-phosphate isomerasePRO_1000013955Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi441772.CLI_3449.

Structurei

3D structure databases

ProteinModelPortaliA7GIL4.
SMRiA7GIL4. Positions 4-449.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000100403.
KOiK01810.
OMAiQVIFIGN.
OrthoDBiEOG64R61J.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A7GIL4 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MENSLSLDLT KTKPYVEEHE IQYLESIIRE MDNTLGKKTG PGNKFLGWMD
60 70 80 90 100
LPINYNKEEF ARIKKAAEKI KNTCDVFIVI GIGGSYLGSR AAIEMISNTF
110 120 130 140 150
YNNLEKNQRR VPQIYFAGNN ISSTYMADLL ELVKDKDICV NVISKSGTTT
160 170 180 190 200
EPAIAFRIFK ELLEKKYGKE GAKERIFATT DVAKGALRTL ADLEGYETFV
210 220 230 240 250
IPDDVGGRFS VLTPVGLLPI AVSGIDVDEM MKGAADARQE YSSDNIEKNH
260 270 280 290 300
VYRYVAVRNA LYRKGKTTEM LVNFEPCLHY FGEWWKQLYG ESEGKDGKGI
310 320 330 340 350
FPAAADFSTD LHSMGQYIQE GLRNIFETFI NVENPRKSII IKEDKENLDG
360 370 380 390 400
LNFLAEKDMD YVNHQALRGT VLAHNDGGVP AIVLNVPELS AYYFGQLVYF
410 420 430 440 450
FEKACGISGY LQGVNPFDQP GVEAYKKNMF ALLGKPGYED MKATLEERLK
Length:450
Mass (Da):50,637
Last modified:September 11, 2007 - v1
Checksum:i78F54CEEFCEC2362
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000728 Genomic DNA. Translation: ABS41702.1.
RefSeqiYP_001392624.1. NC_009699.1.

Genome annotation databases

EnsemblBacteriaiABS41702; ABS41702; CLI_3449.
GeneIDi5405256.
KEGGicbf:CLI_3449.
PATRICi19429827. VBICloBot15611_3325.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000728 Genomic DNA. Translation: ABS41702.1 .
RefSeqi YP_001392624.1. NC_009699.1.

3D structure databases

ProteinModelPortali A7GIL4.
SMRi A7GIL4. Positions 4-449.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 441772.CLI_3449.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABS41702 ; ABS41702 ; CLI_3449 .
GeneIDi 5405256.
KEGGi cbf:CLI_3449.
PATRICi 19429827. VBICloBot15611_3325.

Phylogenomic databases

eggNOGi COG0166.
HOGENOMi HOG000100403.
KOi K01810.
OMAi QVIFIGN.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
UPA00138 .
BioCyci CBOT441772:GJIE-3414-MONOMER.

Family and domain databases

HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Langeland / NCTC 10281 / Type F.

Entry informationi

Entry nameiG6PI_CLOBL
AccessioniPrimary (citable) accession number: A7GIL4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: September 11, 2007
Last modified: October 29, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3