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A7GIL4

- G6PI_CLOBL

UniProt

A7GIL4 - G6PI_CLOBL

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Protein
Glucose-6-phosphate isomerase
Gene
pgi, CLI_3449
Organism
Clostridium botulinum (strain Langeland / NCTC 10281 / Type F)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei291 – 2911Proton donor By similarity
Active sitei312 – 3121 By similarity
Active sitei426 – 4261 By similarity

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciCBOT441772:GJIE-3414-MONOMER.
UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
Phosphoglucose isomerase
Short name:
PGI
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:pgi
Ordered Locus Names:CLI_3449
OrganismiClostridium botulinum (strain Langeland / NCTC 10281 / Type F)
Taxonomic identifieri441772 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
ProteomesiUP000002410: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 450450Glucose-6-phosphate isomeraseUniRule annotation
PRO_1000013955Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi441772.CLI_3449.

Structurei

3D structure databases

ProteinModelPortaliA7GIL4.
SMRiA7GIL4. Positions 4-449.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000100403.
KOiK01810.
OMAiQVIFIGN.
OrthoDBiEOG64R61J.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A7GIL4-1 [UniParc]FASTAAdd to Basket

« Hide

MENSLSLDLT KTKPYVEEHE IQYLESIIRE MDNTLGKKTG PGNKFLGWMD    50
LPINYNKEEF ARIKKAAEKI KNTCDVFIVI GIGGSYLGSR AAIEMISNTF 100
YNNLEKNQRR VPQIYFAGNN ISSTYMADLL ELVKDKDICV NVISKSGTTT 150
EPAIAFRIFK ELLEKKYGKE GAKERIFATT DVAKGALRTL ADLEGYETFV 200
IPDDVGGRFS VLTPVGLLPI AVSGIDVDEM MKGAADARQE YSSDNIEKNH 250
VYRYVAVRNA LYRKGKTTEM LVNFEPCLHY FGEWWKQLYG ESEGKDGKGI 300
FPAAADFSTD LHSMGQYIQE GLRNIFETFI NVENPRKSII IKEDKENLDG 350
LNFLAEKDMD YVNHQALRGT VLAHNDGGVP AIVLNVPELS AYYFGQLVYF 400
FEKACGISGY LQGVNPFDQP GVEAYKKNMF ALLGKPGYED MKATLEERLK 450
Length:450
Mass (Da):50,637
Last modified:September 11, 2007 - v1
Checksum:i78F54CEEFCEC2362
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000728 Genomic DNA. Translation: ABS41702.1.
RefSeqiYP_001392624.1. NC_009699.1.

Genome annotation databases

EnsemblBacteriaiABS41702; ABS41702; CLI_3449.
GeneIDi5405256.
KEGGicbf:CLI_3449.
PATRICi19429827. VBICloBot15611_3325.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000728 Genomic DNA. Translation: ABS41702.1 .
RefSeqi YP_001392624.1. NC_009699.1.

3D structure databases

ProteinModelPortali A7GIL4.
SMRi A7GIL4. Positions 4-449.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 441772.CLI_3449.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABS41702 ; ABS41702 ; CLI_3449 .
GeneIDi 5405256.
KEGGi cbf:CLI_3449.
PATRICi 19429827. VBICloBot15611_3325.

Phylogenomic databases

eggNOGi COG0166.
HOGENOMi HOG000100403.
KOi K01810.
OMAi QVIFIGN.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
UPA00138 .
BioCyci CBOT441772:GJIE-3414-MONOMER.

Family and domain databases

HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Langeland / NCTC 10281 / Type F.

Entry informationi

Entry nameiG6PI_CLOBL
AccessioniPrimary (citable) accession number: A7GIL4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: September 11, 2007
Last modified: June 11, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi