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A7GG48 (ACKA_CLOBL) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 30. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetate kinase
EC=2.7.2.1
Alternative name(s):
Acetokinase
Gene names
Name:ackA
Ordered Locus Names:CLI_2516
OrganismClostridium botulinum (strain Langeland / NCTC 10281 / Type F) [Complete proteome] [HAMAP]
Taxonomic identifier441772 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length397 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020

ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020

Subcellular location

Cytoplasm By similarity HAMAP MF_00020.

Sequence similarities

Belongs to the acetokinase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processorganic acid metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

acetate kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 397397Acetate kinase HAMAP MF_00020
PRO_1000002222

Sequences

Sequence LengthMass (Da)Tools
A7GG48 [UniParc].

Last modified September 11, 2007. Version 1.
Checksum: DF7F213372C51BD3

FASTA39743,474
        10         20         30         40         50         60 
MKILVVNCGS SSLKYQLIDM TSEEALAKGL VERIGIEGSI LTQKVNGEKY IIEEPMKDHK 

        70         80         90        100        110        120 
KAIELVLQAL VDKEHGVISD MSEIAAVGHR VVHGGEKYAS SVLINDEVMK ALEDCVKLAP 

       130        140        150        160        170        180 
LHNPPNIIGI NACRELMPKT PMVAVFDTAF HQTLPDYAYM YPLPYELYEQ NGIRKYGFHG 

       190        200        210        220        230        240 
TSHRYVSSVA SEMMEKDLKD IKVITCHLGN GASLCAVKEG KSVETSMGFT PLAGLAMGTR 

       250        260        270        280        290        300 
CGDIDPAILL FMERELKMSP DEVDTVINKK SGVLGISGVS SDFRDIEGAA EEGNKRAKLA 

       310        320        330        340        350        360 
LDVYHYTVRQ TIGAYTAVLN GVDAIVFTAG LGENSAASRE EILNGLEYLG IKIDAEKNKQ 

       370        380        390 
RGKQIEISTE DSKVKVFVIP TDEELMIARD TKEITAK

« Hide

References

[1]Brinkac L.M., Daugherty S., Dodson R.J., Madupu R., Brown J.L., Bruce D., Detter C., Munk C., Smith L.A., Smith T.J., White O., Brettin T.S.
Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Langeland / NCTC 10281 / Type F.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000728 Genomic DNA. Translation: ABS42544.1.
RefSeqYP_001391758.1. NC_009699.1.

3D structure databases

ProteinModelPortalA7GG48.
SMRA7GG48. Positions 1-394.
ModBaseSearch...

Protein-protein interaction databases

STRINGA7GG48.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5405090.
GenomeReviewsGene locus CLI_2516 in contig CP000728_GR.
KEGGcbf:CLI_2516.
PATRIC19427979. VBICloBot15611_2431.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0282.
HOGENOMHBG285863.
OMALIDMTNE.
ProtClustDBPRK00180.

Enzyme and pathway databases

BioCycCBOT441772:CLI_2516-MONOMER.

Family and domain databases

HAMAPMF_00020. Acetate_kinase.
[Tree]
InterProIPR004372. Ac/Proprionate_kinase.
IPR000890. Aliphatic_acid_kin_short-chain.
IPR023865. Aliphatic_acid_kinase_CS.
[Graphical view]
KOK00925.
PANTHERPTHR21060. Acetate_kin. 1 hit.
PfamPF00871. Acetate_kinase. 1 hit.
[Graphical view]
PIRSFPIRSF000722. Acetate_prop_kin. 1 hit.
PRINTSPR00471. ACETATEKNASE.
TIGRFAMsTIGR00016. AckA. 1 hit.
PROSITEPS01075. ACETATE_KINASE_1. 1 hit.
PS01076. ACETATE_KINASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameACKA_CLOBL
AccessionPrimary (citable) accession number: A7GG48
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: September 11, 2007
Last modified: January 25, 2012
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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