A7GCU9 (A7GCU9_CLOBL) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Thioredoxin reductase RuleBase RU003881
EC=1.8.1.9 RuleBase RU003881

Gene names

Name:	trxB EMBL ABS41074.1
Ordered Locus Names:	CLI_1344

Organism

Clostridium botulinum (strain Langeland / NCTC 10281 / Type F) [Complete proteome] [HAMAP]

Taxonomic identifier

441772 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length	313 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Thioredoxin + NADP+ = thioredoxin disulfide + NADPH. RuleBase RU003881
Cofactor	Binds 1 FAD per subunit By similarity. RuleBase RU003881
Sequence similarities	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family. RuleBase RU003880

Ontologies

Keywords
Domain	Redox-active center RuleBase RU003880
Ligand	FAD RuleBase RU003880 Flavoprotein RuleBase RU003880
Molecular function	Oxidoreductase RuleBase RU003880 EMBL ABS41074.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	removal of superoxide radicals Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	flavin adenine dinucleotide binding Inferred from electronic annotation. Source: InterPro thioredoxin-disulfide reductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A7GCU9 [UniParc]. Last modified September 11, 2007. Version 1. Checksum: 614F87C011EE489D	FASTA	313	34,226
	10 20 30 40 50 60 MENLYDVIII GSGPAGLSAG LYAARARLKT LILERNKAGG QIVITDEVAN YPGSIRDATG 70 80 90 100 110 120 ASLVARMEEQ VDEFGAERKK DNVKEVDFTG KIKIIKGEKE EYKAKSVIIA TGAAPRHIGC 130 140 150 160 170 180 KGENELIGKG VSYCATCDAD FFTDLEVFVI GGGDSALEEA LYLTKFARKV TVVHRRDALR 190 200 210 220 230 240 GAKSIQEKVF KNPKIEIMWD SVVEEIKGDG IVESAVFKNK KTGEITEYFA DEDDGTFGIF 250 260 270 280 290 300 VFVGYLPINN LFKDIVTMNE AGYIKTNDRM ETNIEGIFAA GDIREKSLRQ VVTAAADGAI 310 AAVEAYKYVE DTF

References

[1]	Brinkac L.M., Daugherty S., Dodson R.J., Madupu R., Brown J.L., Bruce D., Detter C., Munk C., Smith L.A., Smith T.J., White O., Brettin T.S. Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000728 Genomic DNA. Translation: ABS41074.1.
RefSeq	YP_001390609.1. NC_009699.1.
3D structure databases
ProteinModelPortal	A7GCU9.
ModBase	Search...
Protein-protein interaction databases
STRING	A7GCU9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5402453.
GenomeReviews	Gene locus CLI_1344 in contig CP000728_GR.
KEGG	cbf:CLI_1344.
PATRIC	19425641. VBICloBot15611_1262.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0492.
HOGENOM	HBG669726.
OMA	GEEREFP.
ProtClustDB	CLSK966045.
Family and domain databases
InterPro	IPR013027. FAD_pyr_nucl-diS_OxRdtase. IPR008255. Pyr_nucl-diS_OxRdtase_2_AS. IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD. IPR001327. Pyr_OxRdtase_NAD-bd_dom. IPR000103. Pyridine_nuc-diS_OxRdtase_2. IPR005982. Thioredox_Rdtase. [Graphical view]
KO	K00384.
Pfam	PF00070. Pyr_redox. 1 hit. PF07992. Pyr_redox_2. 1 hit. [Graphical view]
PRINTS	PR00368. FADPNR. PR00469. PNDRDTASEII.
TIGRFAMs	TIGR01292. TRX_reduct. 1 hit.
PROSITE	PS00573. PYRIDINE_REDOX_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A7GCU9_CLOBL

Accession

Primary (citable) accession number: A7GCU9

Entry history

Integrated into UniProtKB/TrEMBL:	September 11, 2007
Last sequence update:	September 11, 2007
Last modified:	December 14, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)