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A7G9Y0

- PGK_CLOBL

UniProt

A7G9Y0 - PGK_CLOBL

Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Clostridium botulinum (strain Langeland / NCTC 10281 / Type F)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 46 (01 Oct 2014)
      Sequence version 1 (11 Sep 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei38 – 381SubstrateUniRule annotation
    Binding sitei122 – 1221SubstrateUniRule annotation
    Binding sitei155 – 1551SubstrateUniRule annotation
    Binding sitei206 – 2061ATPUniRule annotation
    Binding sitei297 – 2971ATP; via carbonyl oxygenUniRule annotation
    Binding sitei328 – 3281ATPUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi354 – 3574ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciCBOT441772:GJIE-272-MONOMER.
    UniPathwayiUPA00109; UER00185.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
    Gene namesi
    Name:pgkUniRule annotation
    Ordered Locus Names:CLI_0292
    OrganismiClostridium botulinum (strain Langeland / NCTC 10281 / Type F)
    Taxonomic identifieri441772 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
    ProteomesiUP000002410: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 398398Phosphoglycerate kinasePRO_1000009608Add
    BLAST

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    STRINGi441772.CLI_0292.

    Structurei

    3D structure databases

    ProteinModelPortaliA7G9Y0.
    SMRiA7G9Y0. Positions 4-398.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni23 – 253Substrate bindingUniRule annotation
    Regioni61 – 644Substrate bindingUniRule annotation

    Sequence similaritiesi

    Belongs to the phosphoglycerate kinase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0126.
    HOGENOMiHOG000227108.
    KOiK00927.
    OMAiWEALDIG.
    OrthoDBiEOG64N9Z0.

    Family and domain databases

    Gene3Di3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPiMF_00145. Phosphoglyc_kinase.
    InterProiIPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015911. Phosphoglycerate_kinase_CS.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view]
    PANTHERiPTHR11406. PTHR11406. 1 hit.
    PfamiPF00162. PGK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000724. Pgk. 1 hit.
    PRINTSiPR00477. PHGLYCKINASE.
    SUPFAMiSSF53748. SSF53748. 1 hit.
    PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A7G9Y0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNYNKKSIED IDVKGKKVLV RCDFNVPLNE GKITDENRLV GALPTIKYLM    50
    GKGAKIILCS HMGKPKGEPK KELSLLPVAK RLSEMLNKEV IFADDDNVVG 100
    ENAKKAVEDM KDGDVVLLQN TRYRKEETKN EEVFSKELAS LADVFVNDAF 150
    GTAHRAHCST VGVTNYLKEA ACGYLIQKEL KFLGNAVEKP ERPFVAILGG 200
    AKVSDKINVI NNLLDKVDTL IIGGGMGYTF LKAQGYTIGN SLVEEDKVEY 250
    SKEMIDKAKE KGVNLLLPID NVVADKFDKD ASPVVTEDQN IGEGYMGLDI 300
    GPKTAKIYSD AIKSAKTVVW NGPMGVFEFK SFANGTIEVA KAMADSDAVT 350
    IIGGGDSAAA VNILGFGDKM THISTGGGAS LEFLEGKELP GIAALNDK 398
    Length:398
    Mass (Da):42,976
    Last modified:September 11, 2007 - v1
    Checksum:iEF719E8CA23238CD
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000728 Genomic DNA. Translation: ABS42835.1.
    RefSeqiWP_011987290.1. NC_009699.1.
    YP_001389590.1. NC_009699.1.

    Genome annotation databases

    EnsemblBacteriaiABS42835; ABS42835; CLI_0292.
    GeneIDi5405290.
    KEGGicbf:CLI_0292.
    PATRICi19423540. VBICloBot15611_0219.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000728 Genomic DNA. Translation: ABS42835.1 .
    RefSeqi WP_011987290.1. NC_009699.1.
    YP_001389590.1. NC_009699.1.

    3D structure databases

    ProteinModelPortali A7G9Y0.
    SMRi A7G9Y0. Positions 4-398.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 441772.CLI_0292.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABS42835 ; ABS42835 ; CLI_0292 .
    GeneIDi 5405290.
    KEGGi cbf:CLI_0292.
    PATRICi 19423540. VBICloBot15611_0219.

    Phylogenomic databases

    eggNOGi COG0126.
    HOGENOMi HOG000227108.
    KOi K00927.
    OMAi WEALDIG.
    OrthoDBi EOG64N9Z0.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00185 .
    BioCyci CBOT441772:GJIE-272-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPi MF_00145. Phosphoglyc_kinase.
    InterProi IPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015911. Phosphoglycerate_kinase_CS.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view ]
    PANTHERi PTHR11406. PTHR11406. 1 hit.
    Pfami PF00162. PGK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000724. Pgk. 1 hit.
    PRINTSi PR00477. PHGLYCKINASE.
    SUPFAMi SSF53748. SSF53748. 1 hit.
    PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Langeland / NCTC 10281 / Type F.

    Entry informationi

    Entry nameiPGK_CLOBL
    AccessioniPrimary (citable) accession number: A7G9Y0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: September 11, 2007
    Last modified: October 1, 2014
    This is version 46 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3