Skip Header

Contribute Send feedback
Read comments (?) or add your own

A7FYA1 (A7FYA1_CLOB1) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesSubmitted name:
Dihydrodipicolinate synthase EMBL ABS33757.1
EC=4.2.1.52 EMBL ABS33757.1
Gene names
Name:dapA EMBL ABS33757.1
Ordered Locus Names:CLB_3187
OrganismClostridium botulinum (strain ATCC 19397 / Type A) [Complete proteome] [HAMAP]
Taxonomic identifier441770 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length292 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

L-aspartate 4-semialdehyde + pyruvate = dihydrodipicolinate + 2 H2O. SAAS SAAS005263

Pathway

Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 3/4. SAAS SAAS005263

Subcellular location

Cytoplasm By similarity SAAS SAAS005263.

Sequences

Sequence LengthMass (Da)Tools
A7FYA1 [UniParc].

Last modified September 11, 2007. Version 1.
Checksum: A75FF4051E4840D9

FASTA29231,651
        10         20         30         40         50         60 
MSIFKGSGVA IITPFTNTGV DFDKLSELIE WHIKSKTDAI IVCGTTGEAT TMTETERKET 

        70         80         90        100        110        120 
IKFVIDKVNK RIPVIAGTGS NNTAASIAMS KWAESIGVDG LLVITPYYNK TTQKGLVKHF 

       130        140        150        160        170        180 
KAVSDAVSTP IIIYNVPGRT GLNITPGTLK ELCEDKNIVA VKEASGNISQ IAQIKALCGD 

       190        200        210        220        230        240 
KLDIYSGNDD QIIPILALGG IGVISVLANV IPEDVHNMCE LYLNGKVNEA LKIQLDSLAL 

       250        260        270        280        290 
TNALFIETNP IPVKTAMNLM NMKVGDLRLP LCEMNENNLE ILKKELKAYN LM

« Hide

References

« Hide 'large scale' references
[1]"Analysis of the neurotoxin complex genes in Clostridium botulinum A1-A4 and B1 strains: BoNT/A3, /Ba4 and /B1 clusters are located within plasmids."
Smith T.J., Hill K.K., Foley B.T., Detter J.C., Munk A.C., Bruce D.C., Doggett N.A., Smith L.A., Marks J.D., Xie G., Brettin T.S.
PLoS ONE 2:E1271-E1271(2007) [PubMed: 18060065] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"The high resolution structure of DHDPS from Clostridium botulinum."
Dobson R.C.J., Atkinson S.
Submitted (AUG-2009) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.19 ANGSTROMS) OF 2-292.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000726 Genomic DNA. Translation: ABS33757.1.
RefSeqYP_001385474.1. NC_009697.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3A5FX-ray1.19A/B2-292[»]
ProteinModelPortalA7FYA1.
ModBaseSearch...

Protein-protein interaction databases

STRINGA7FYA1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5397783.
GenomeReviewsGene locus CLB_3187 in contig CP000726_GR.
KEGGcba:CLB_3187.
PATRIC19360920. VBICloBot110701_3087.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0329.
HOGENOMHBG358848.
OMACEMEDSN.
ProtClustDBPRK03170.

Family and domain databases

InterProIPR013785. Aldolase_TIM.
IPR002220. Dihydrodipicolinate_synth-like.
IPR020625. Dihydrodipicolinate_synth_AS.
IPR020624. Dihydrodipicolinate_synth_CS.
IPR005263. Dihydrodipicolinate_synth_DapA.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK01714.
PANTHERPTHR12128. DHDPS. 1 hit.
PfamPF00701. DHDPS. 1 hit.
[Graphical view]
PIRSFPIRSF001365. DHDPS. 1 hit.
PRINTSPR00146. DHPICSNTHASE.
TIGRFAMsTIGR00674. DapA. 1 hit.
PROSITEPS00665. DHDPS_1. 1 hit.
PS00666. DHDPS_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA7FYA1_CLOB1
AccessionPrimary (citable) accession number: A7FYA1
Entry history
Integrated into UniProtKB/TrEMBL: September 11, 2007
Last sequence update: September 11, 2007
Last modified: December 14, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info