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A7FJ17 (DCYD_YERP3) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
D-cysteine desulfhydrase

EC=4.4.1.15
Gene names
Name:dcyD
Ordered Locus Names:YpsIP31758_2275
OrganismYersinia pseudotuberculosis serotype O:1b (strain IP 31758) [Complete proteome] [HAMAP]
Taxonomic identifier349747 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia

Protein attributes

Sequence length330 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the alpha,beta-elimination reaction of D-cysteine and of several D-cysteine derivatives. It could be a defense mechanism against D-cysteine By similarity. HAMAP-Rule MF_01045

Catalytic activity

D-cysteine + H2O = H2S + NH3 + pyruvate. HAMAP-Rule MF_01045

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01045

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_01045

Sequence similarities

Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

Ontologies

Keywords
   LigandPyridoxal phosphate
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processD-amino acid metabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionD-cysteine desulfhydrase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 330330D-cysteine desulfhydrase HAMAP-Rule MF_01045
PRO_1000064270

Amino acid modifications

Modified residue521N6-(pyridoxal phosphate)lysine By similarity

Sequences

Sequence LengthMass (Da)Tools
A7FJ17 [UniParc].

Last modified September 11, 2007. Version 1.
Checksum: 536FD64B267091A5

FASTA33035,048
        10         20         30         40         50         60 
MTLQHKLTQF PRLDLVGNAT PLEKLSRLSD YLGREIYIKR DDVTPVALGG NKLRKLEFLA 

        70         80         90        100        110        120 
ADALRQGADT LVTAGAIQSN HVRQTAAVAA KLGLHCVALL ENPIGTEQAN YLTNGNRLLL 

       130        140        150        160        170        180 
DLFNVDVVMC EALNDPNQQL AELATRVEAQ GFRPYVVPIG GSNALGALGY VQCSLEIAAQ 

       190        200        210        220        230        240 
AAGNVAFSSV VVASGSAGTH AGLAVGLQQL LPDAELIGVT VSRSADEQRP KVAQIQQALA 

       250        260        270        280        290        300 
TSLGMTDPLA KITLWDSYFA PQYGMPNEEG IAAIKLLARL EGILLDPVYT GKAMAGLLDG 

       310        320        330 
IEQQKFCDKG PILFIHTGGA PALFAYHPQV 

« Hide

References

[1]"The complete genome sequence of Yersinia pseudotuberculosis IP31758, the causative agent of Far East scarlet-like fever."
Eppinger M., Rosovitz M.J., Fricke W.F., Rasko D.A., Kokorina G., Fayolle C., Lindler L.E., Carniel E., Ravel J.
PLoS Genet. 3:1508-1523(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: IP 31758.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000720 Genomic DNA. Translation: ABS49548.1.
RefSeqYP_001401245.1. NC_009708.1.

3D structure databases

ProteinModelPortalA7FJ17.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING349747.YpsIP31758_2275.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABS49548; ABS49548; YpsIP31758_2275.
GeneID5387537.
KEGGypi:YpsIP31758_2275.
PATRIC18633485. VBIYerPse15693_2681.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2515.
HOGENOMHOG000022459.
KOK05396.
OMADRYHAGT.
OrthoDBEOG6FBX0P.

Enzyme and pathway databases

BioCycYPSE349747:GH71-2328-MONOMER.

Family and domain databases

HAMAPMF_01045. D_Cys_desulfhydr.
InterProIPR027278. ACCD_DCysDesulf.
IPR005966. D-Cys_desShydrase.
IPR023702. D_Cys_desulphydr_bac.
IPR001926. Trp_syn_b_sub_like_PLP_eny_SF.
[Graphical view]
PfamPF00291. PALP. 1 hit.
[Graphical view]
PIRSFPIRSF006278. ACCD_DCysDesulf. 1 hit.
SUPFAMSSF53686. SSF53686. 1 hit.
TIGRFAMsTIGR01275. ACC_deam_rel. 1 hit.
ProtoNetSearch...

Entry information

Entry nameDCYD_YERP3
AccessionPrimary (citable) accession number: A7FJ17
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: September 11, 2007
Last modified: May 14, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families