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Protein

UvrABC system protein C

Gene

uvrC

Organism
Yersinia pseudotuberculosis serotype O:1b (strain IP 31758)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionExcision nuclease
Biological processDNA damage, DNA excision, DNA repair, SOS response

Names & Taxonomyi

Protein namesi
Recommended name:
UvrABC system protein CUniRule annotation
Short name:
Protein UvrCUniRule annotation
Alternative name(s):
Excinuclease ABC subunit CUniRule annotation
Gene namesi
Name:uvrCUniRule annotation
Ordered Locus Names:YpsIP31758_2252
OrganismiYersinia pseudotuberculosis serotype O:1b (strain IP 31758)
Taxonomic identifieri349747 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesYersiniaceaeYersinia
Proteomesi
  • UP000002412 Componenti: Chromosome

Subcellular locationi

A7FIZ3:
  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000778601 – 610UvrABC system protein CAdd BLAST610

Interactioni

Subunit structurei

Interacts with UvrB in an incision complex.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliA7FIZ3.
SMRiA7FIZ3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 94GIY-YIGUniRule annotationAdd BLAST79
Domaini204 – 239UVRUniRule annotationAdd BLAST36

Sequence similaritiesi

Belongs to the UvrC family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000279961.
KOiK03703.
OMAiLFPIRQC.

Family and domain databases

Gene3Di3.40.1440.10. 1 hit.
4.10.860.10. 1 hit.
HAMAPiMF_00203. UvrC. 1 hit.
InterProiView protein in InterPro
IPR000305. GIY-YIG_endonuc.
IPR035901. GIY-YIG_endonuc_sf.
IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
IPR010994. RuvA_2-like.
IPR001943. UVR_dom.
IPR036876. UVR_dom_sf.
IPR004791. UvrC.
IPR001162. UvrC_homol_region.
PfamiView protein in Pfam
PF01541. GIY-YIG. 1 hit.
PF02151. UVR. 1 hit.
PF08459. UvrC_HhH_N. 1 hit.
SMARTiView protein in SMART
SM00465. GIYc. 1 hit.
SM00278. HhH1. 2 hits.
SUPFAMiSSF46600. SSF46600. 1 hit.
SSF47781. SSF47781. 1 hit.
SSF82771. SSF82771. 1 hit.
TIGRFAMsiTIGR00194. uvrC. 1 hit.
PROSITEiView protein in PROSITE
PS50164. GIY_YIG. 1 hit.
PS50151. UVR. 1 hit.
PS50165. UVRC. 1 hit.

Sequencei

Sequence statusi: Complete.

A7FIZ3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDLFDYKEF LKTVTSQPGV YRMYDTAGTV IYVGKAKDLK KRLTSYFRAQ
60 70 80 90 100
VANRKTETLV KNIAQIDVTV THTETEALLL EHNYIKLYQP RYNVLLRDDK
110 120 130 140 150
SYPLIFLSAD EHPRLAVHRG AKHEKGEYFG PFPNSYAVRE TLALLQKLFP
160 170 180 190 200
VRQCENSVYR NRSRPCLQYQ IGRCSGPCVE GLVSEEEYQR QVDYVRLFLS
210 220 230 240 250
GKDQQVLTQL ITRMEEASQQ LHFEDAARIR DQIQAVRRVT EQQFVSGDSE
260 270 280 290 300
DLDVIGVAFD AGLACVHVLF IRLGKVLGSR SYFPKVPAGT ELSEVVQTFV
310 320 330 340 350
GQFYLQGSQG RTLPGEILLD FTLTEKDLLA SSLSELAGRK IQIQSRPRGD
360 370 380 390 400
RARYLKLART NASTALITRL SQQSTIHQRM KELAKVLKLD EINRMECFDI
410 420 430 440 450
SHTMGEQTVA SCVVFDANGP VRSEYRRYNI SGITPGDDYA AMAQVLKRRY
460 470 480 490 500
GKALDDQKIP DVIFIDGGKG QLSQAFDVFA SLNVPWDKQK PLLVGVAKGS
510 520 530 540 550
DRKAGLETLF LASEGEGFSL PPDSPALHLI QHIRDDSHNH AITGHRQRRS
560 570 580 590 600
KVKNTSALEM IEGVGPKRRQ VLLKYMGGLQ PLFNASVEEI AKVPGISQAL
610
AEKIHNALKH
Length:610
Mass (Da):68,693
Last modified:September 11, 2007 - v1
Checksum:iF293BCE633F76E7B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000720 Genomic DNA. Translation: ABS48878.1.

Genome annotation databases

EnsemblBacteriaiABS48878; ABS48878; YpsIP31758_2252.
KEGGiypi:YpsIP31758_2252.

Similar proteinsi

Entry informationi

Entry nameiUVRC_YERP3
AccessioniPrimary (citable) accession number: A7FIZ3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: September 11, 2007
Last modified: October 25, 2017
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families