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A7FIL4 (A7FIL4_YERP3) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
N-succinylglutamate 5-semialdehyde dehydrogenase HAMAP MF_01174
EC=1.2.1.71 HAMAP MF_01174
Alternative name(s):
Succinylglutamic semialdehyde dehydrogenase HAMAP MF_01174
Gene names
Name:astD HAMAP MF_01174
Ordered Locus Names:YpsIP31758_2119
OrganismYersinia pseudotuberculosis serotype O:1b (strain IP 31758) [Complete proteome] [HAMAP] EMBL ABS46000.1
Taxonomic identifier349747 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Yersinia

Protein attributes

Sequence length500 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate By similarity. HAMAP MF_01174

Catalytic activity

N-succinyl-L-glutamate 5-semialdehyde + NAD+ + H2O = N-succinyl-L-glutamate + NADH. HAMAP MF_01174

Pathway

Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 4/5. HAMAP MF_01174

Sequence similarities

Belongs to the aldehyde dehydrogenase family. AstD subfamily. HAMAP MF_01174

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding229 – 2346NAD By similarity HAMAP MF_01174

Sites

Active site2521 By similarity HAMAP MF_01174
Active site2861 By similarity HAMAP MF_01174

Sequences

Sequence LengthMass (Da)Tools
A7FIL4 [UniParc].

Last modified September 11, 2007. Version 1.
Checksum: B290DCB9FD760E58

FASTA50054,214
        10         20         30         40         50         60 
MFNAVLSSHP ALFIQGEWRI GNGVSFEKQD PMSQQRLWQA RAADHTDVTL ACHAARAAFP 

        70         80         90        100        110        120 
AWARASLEQR ATVIQQFAAL LEQHKQSLAR TISLETSKPY WETLTEVQAM IGKVAISLQA 

       130        140        150        160        170        180 
YQTRTGHSQT PMGDSMSVLR HRPHGVLAVF GPYNFPGHLP NGHIVPALLA GNTVVFKPSE 

       190        200        210        220        230        240 
LTPWTAEETV KLWQEAGIPD GVLNLVQGGR ETGEALAAQP DIDGLLFTGS AHTGYHLHRQ 

       250        260        270        280        290        300 
LAGQPEKMLA LEMGGNNALI VEQVKDRDAV VNLAIQSAFI SAGQRCTCSR RLLVKTGAEG 

       310        320        330        340        350        360 
DAFLLRFTAV AQALRIGRWD EQPAPFMGAV ISSQAAERML AAQQHLLLLG GESLLNMTRP 

       370        380        390        400        410        420 
DSQSALLTPG IIDITNISEV PDEEYFGPLV SVIRYTDFTE ALKIANQTRF GLAVGLVSED 

       430        440        450        460        470        480 
RQQFEQLLLE ARAGIVNWNK PLTGASSAAP FGGVGASGNH RPSAFYAADY CAWPMASLEC 

       490        500 
EHLMLPVTLS PGISFDLPKA

« Hide

References

[1]"The complete genome sequence of Yersinia pseudotuberculosis IP31758, the causative agent of Far East scarlet-like fever."
Eppinger M., Rosovitz M.J., Fricke W.F., Rasko D.A., Kokorina G., Fayolle C., Lindler L.E., Carniel E., Ravel J.
PLoS Genet. 3:1508-1523(2007) [PubMed: 17784789] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000720 Genomic DNA. Translation: ABS46000.1.
RefSeqYP_001401092.1. NC_009708.1.

3D structure databases

ProteinModelPortalA7FIL4.
ModBaseSearch...

Protein-protein interaction databases

STRINGA7FIL4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5388508.
GenomeReviewsGene locus YpsIP31758_2119 in contig CP000720_GR.
KEGGypi:YpsIP31758_2119.
NMPDRfig|349747.3.peg.420.
PATRIC18633132. VBIYerPse15693_2509.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1012.
HOGENOMHBG752218.
OMAMTQRDPR.
ProtClustDBPRK09457.

Enzyme and pathway databases

BioCycYPSE349747:YPSIP31758_2119-MONOMER.

Family and domain databases

HAMAPMF_01174. Aldedh_AstD.
[Tree]
InterProIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
IPR017649. SuccinylGlu_semiald_DH_AstD.
[Graphical view]
Gene3DG3DSA:3.40.309.10. Aldehyde_dehydrogenase_C. 1 hit.
G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit.
KOK06447.
PANTHERPTHR11699:SF24. PTHR11699:SF24. 1 hit.
PfamPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMSSF53720. Aldehyde_DH/Histidinol_DH. 1 hit.
TIGRFAMsTIGR03240. Arg_catab_astD. 1 hit.
PROSITEPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA7FIL4_YERP3
AccessionPrimary (citable) accession number: A7FIL4
Entry history
Integrated into UniProtKB/TrEMBL: September 11, 2007
Last sequence update: September 11, 2007
Last modified: December 14, 2011
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info