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A7FHA1 (A7FHA1_YERP3) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length409 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 SAAS SAAS020622

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS020622

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site761Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site3011Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1751Substrate By similarity HAMAP-Rule MF_01201
Binding site3491Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue761N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
A7FHA1 [UniParc].

Last modified September 11, 2007. Version 1.
Checksum: BBFCC8C5A2E4241C

FASTA40944,770
        10         20         30         40         50         60 
MHVRFRHLFL LPLITLVACS QPVSKNHLSL TSLSANAQQP VVNNAWLEIS QGALDFNTKK 

        70         80         90        100        110        120 
MLTLLDNKST LCAILKGDAY GHDLTLVTPV MLKNNVQCIG VASNQELKTV RDLGFTGQLI 

       130        140        150        160        170        180 
RVRSATLKEM QQAMAYDVEE LIGDKTVAEQ LNNIAKLNGK VLRIHLALNS AGMSRNGLEV 

       190        200        210        220        230        240 
SKARGLNDAK TIAGLKNLTI VGIMSHYPVE DASEIKADLA RFQQQAKDVI AVTGLKREKI 

       250        260        270        280        290        300 
KLHVANTFAT LAVPDSWLDM VRVGGVFYGD TIASTEYKRV MTFKSNIASL NNYPKGGTVG 

       310        320        330        340        350        360 
YDRTYTLKRD SLLANIPVGY ADGYRRVFSN AGHVIIQGQR LPVLGKTSMN TVIVDVTDLK 

       370        380        390        400 
KVSLGDEVVL FGKQGNAEIQ AEEIEDLSGA LFTEMSILWG ATNKRILVD 

« Hide

References

[1]"The complete genome sequence of Yersinia pseudotuberculosis IP31758, the causative agent of Far East scarlet-like fever."
Eppinger M., Rosovitz M.J., Fricke W.F., Rasko D.A., Kokorina G., Fayolle C., Lindler L.E., Carniel E., Ravel J.
PLoS Genet. 3:1508-1523(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: IP 31758 EMBL ABS49698.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000720 Genomic DNA. Translation: ABS49698.1.
RefSeqYP_001400629.1. NC_009708.1.

3D structure databases

ProteinModelPortalA7FHA1.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING349747.YpsIP31758_1652.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABS49698; ABS49698; YpsIP31758_1652.
GeneID5388503.
KEGGypi:YpsIP31758_1652.
PATRIC18632124. VBIYerPse15693_2010.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0787.
HOGENOMHOG000279190.
KOK01775.
OMAQQIPCVA.
OrthoDBEOG6PP9NJ.

Enzyme and pathway databases

BioCycYPSE349747:GH71-1693-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA7FHA1_YERP3
AccessionPrimary (citable) accession number: A7FHA1
Entry history
Integrated into UniProtKB/TrEMBL: September 11, 2007
Last sequence update: September 11, 2007
Last modified: July 9, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)