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A7FH52 (NAGK_YERP3) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
N-acetyl-D-glucosamine kinase

EC=2.7.1.59
Alternative name(s):
GlcNAc kinase
Gene names
Name:nagK
Ordered Locus Names:YpsIP31758_1603
OrganismYersinia pseudotuberculosis serotype O:1b (strain IP 31758) [Complete proteome] [HAMAP]
Taxonomic identifier349747 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia

Protein attributes

Sequence length304 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P By similarity. HAMAP-Rule MF_01271

Catalytic activity

ATP + N-acetyl-D-glucosamine = ADP + N-acetyl-D-glucosamine 6-phosphate. HAMAP-Rule MF_01271

Pathway

Cell wall biogenesis; peptidoglycan recycling. HAMAP-Rule MF_01271

Sequence similarities

Belongs to the ROK (NagC/XylR) family. NagK subfamily.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 304304N-acetyl-D-glucosamine kinase HAMAP-Rule MF_01271
PRO_1000067381

Regions

Nucleotide binding4 – 118ATP Potential
Nucleotide binding133 – 1408ATP Potential

Sites

Metal binding1571Zinc By similarity
Metal binding1771Zinc By similarity
Metal binding1791Zinc By similarity
Metal binding1841Zinc By similarity

Sequences

Sequence LengthMass (Da)Tools
A7FH52 [UniParc].

Last modified September 11, 2007. Version 1.
Checksum: 846570FFD39100BA

FASTA30433,302
        10         20         30         40         50         60 
MYYGFDMGGT KIELGVFDEN LQRIWHKRVP TPREDYPQLL QILRDLTEEA DTYCGVQGSV 

        70         80         90        100        110        120 
GIGIPGLPNA DDGTVFTANV PSAMGQPLQA DLSRLIQREV RIDNDANCFA LSEAWDPEFR 

       130        140        150        160        170        180 
TYPTVLGLIL GTGVGGGLIV NGSIVSGRNH ITGEFGHFRL PVDALDILGA DIPHVPCGCG 

       190        200        210        220        230        240 
HRGCIENYIS GRGFEWMYSH FYQHTLPATD IIAHYAAGEP KAVAHVERFM DVLAVCLGNL 

       250        260        270        280        290        300 
LTMLDPHLVV VGGGLSNFEK IYQELPKRLP AHLLRVARLP RIEKARYGDS GGVRGAAFLH 


LAEK 

« Hide

References

[1]"The complete genome sequence of Yersinia pseudotuberculosis IP31758, the causative agent of Far East scarlet-like fever."
Eppinger M., Rosovitz M.J., Fricke W.F., Rasko D.A., Kokorina G., Fayolle C., Lindler L.E., Carniel E., Ravel J.
PLoS Genet. 3:1508-1523(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: IP 31758.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000720 Genomic DNA. Translation: ABS48486.1.
RefSeqYP_001400580.1. NC_009708.1.

3D structure databases

ProteinModelPortalA7FH52.
SMRA7FH52. Positions 1-303.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING349747.YpsIP31758_1603.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABS48486; ABS48486; YpsIP31758_1603.
GeneID5386543.
KEGGypi:YpsIP31758_1603.
PATRIC18632018. VBIYerPse15693_1957.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1940.
HOGENOMHOG000150087.
KOK00884.
OMAWIGNDAD.
OrthoDBEOG61P6P0.
ProtClustDBPRK13310.

Enzyme and pathway databases

BioCycYPSE349747:GH71-1643-MONOMER.
UniPathwayUPA00544.

Family and domain databases

HAMAPMF_01271. GlcNAc_kinase.
InterProIPR023505. N-acetyl-D-glucosamine_kinase.
IPR000600. ROK.
[Graphical view]
PfamPF00480. ROK. 1 hit.
[Graphical view]
PROSITEPS01125. ROK. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameNAGK_YERP3
AccessionPrimary (citable) accession number: A7FH52
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: September 11, 2007
Last modified: April 16, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways