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A7FD23 (A7FD23_YERP3) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein attributes

Sequence length548 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

2 pyruvate = 2-acetolactate + CO2.

Cofactor

Binds 1 magnesium ion per subunit By similarity.

Binds 1 thiamine pyrophosphate per subunit By similarity.

Pathway

Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 1/4.

Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 1/4.

Sequence similarities

Belongs to the TPP enzyme family. RuleBase RU003702

Sequences

Sequence LengthMass (Da)Tools
A7FD23 [UniParc].

Last modified September 11, 2007. Version 1.
Checksum: 51C9B4D4F397D2D5

FASTA54858,785
        10         20         30         40         50         60 
MNGAQWVVQA LRAQGVDTVF GYPGGAIMPV YDALYDGGVE HLLCRHEQGA AIAAIGYARA 

        70         80         90        100        110        120 
TGKVGVCIAT SGPGATNLIT GLADALLDSV PVIAITGQVG SALIGTDAFQ EIDVLGLSLA 

       130        140        150        160        170        180 
CTKHSFLVES LDALPEIMAE AFAIATSGRP GPVLIDIPKD IQLAVGELTP HLKPVEEHSV 

       190        200        210        220        230        240 
DSAAELQHAW DMLANAQKPM LYVGGGVGMA QAVPALRDFI AMTGIPAVAT LKGLGAPDIA 

       250        260        270        280        290        300 
HPCYLGMLGM HGTKAANFAV QDCDLLVAVG ARFDDRVTGK LNTFASKAKV IHMDIDPAEL 

       310        320        330        340        350        360 
GKLRQVHVAL QGNLNVLLPA LQQPLNIQSW RDEVMALKQQ HHWRYDHPGQ AIYAPLLLKQ 

       370        380        390        400        410        420 
ISERKAPETV VTTDVGQHQM WTAQHMNFTR PENFITSSGL GTMGFGVPAA VGAQMARPDD 

       430        440        450        460        470        480 
MVICVSGDGS FMMNVQELGT IKRKQLPLKI VLLDNQRLGM VRQWQQLFFD GRYSETNLSD 

       490        500        510        520        530        540 
NPDFITLASA FDIPGQRITR KDQVDAALDA LFNSEGPYLL QVSIDELENV WPLVPPGAGN 


ETMLEKIS 

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References

[1]"The complete genome sequence of Yersinia pseudotuberculosis IP31758, the causative agent of Far East scarlet-like fever."
Eppinger M., Rosovitz M.J., Fricke W.F., Rasko D.A., Kokorina G., Fayolle C., Lindler L.E., Carniel E., Ravel J.
PLoS Genet. 3:1508-1523(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: IP 31758 EMBL ABS46384.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000720 Genomic DNA. Translation: ABS46384.1.
RefSeqYP_001399151.1. NC_009708.1.

3D structure databases

ProteinModelPortalA7FD23.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING349747.YpsIP31758_0154.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABS46384; ABS46384; YpsIP31758_0154.
GeneID5386827.
KEGGypi:YpsIP31758_0154.
PATRIC18628798. VBIYerPse15693_0376.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0028.
HOGENOMHOG000258448.
KOK01652.
OMADEHENVW.
OrthoDBEOG6KT2NW.

Enzyme and pathway databases

BioCycYPSE349747:GH71-160-MONOMER.
UniPathwayUPA00047; UER00055.
UPA00049; UER00059.

Family and domain databases

Gene3D3.40.50.1220. 1 hit.
3.40.50.970. 2 hits.
InterProIPR012846. Acetolactate_synth_lsu.
IPR029035. DHS-like_NAD/FAD-binding_dom.
IPR029061. THDP-binding.
IPR012000. Thiamin_PyroP_enz_cen_dom.
IPR012001. Thiamin_PyroP_enz_TPP-bd_dom.
IPR000399. TPP-bd_CS.
IPR011766. TPP_enzyme-bd_C.
[Graphical view]
PfamPF02775. TPP_enzyme_C. 1 hit.
PF00205. TPP_enzyme_M. 1 hit.
PF02776. TPP_enzyme_N. 1 hit.
[Graphical view]
SUPFAMSSF52467. SSF52467. 1 hit.
SSF52518. SSF52518. 2 hits.
TIGRFAMsTIGR00118. acolac_lg. 1 hit.
PROSITEPS00187. TPP_ENZYMES. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA7FD23_YERP3
AccessionPrimary (citable) accession number: A7FD23
Entry history
Integrated into UniProtKB/TrEMBL: September 11, 2007
Last sequence update: September 11, 2007
Last modified: June 11, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)