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A7EQZ1 (DAPB_SCLS1) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable dipeptidyl-aminopeptidase B

Short name=DPAP B
EC=3.4.14.5
Gene names
Name:dapB
ORF Names:SS1G_07744
OrganismSclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1) (White mold) (Whetzelinia sclerotiorum) [Reference proteome]
Taxonomic identifier665079 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaLeotiomycetesHelotialesSclerotiniaceaeSclerotinia

Protein attributes

Sequence length921 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Type IV dipeptidyl-peptidase which removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline By similarity.

Catalytic activity

Release of an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, from a polypeptide, preferentially when Yaa is Pro, provided Zaa is neither Pro nor hydroxyproline.

Subcellular location

Vacuole membrane; Single-pass type II membrane protein By similarity. Note: Lysosome-like vacuoles By similarity.

Sequence similarities

Belongs to the peptidase S9B family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 921921Probable dipeptidyl-aminopeptidase B
PRO_0000412162

Regions

Topological domain1 – 109109Cytoplasmic Potential
Transmembrane110 – 13021Helical; Signal-anchor for type II membrane protein; Potential
Topological domain131 – 921791Vacuolar Potential

Sites

Active site7681Charge relay system By similarity
Active site8451Charge relay system By similarity
Active site8781Charge relay system By similarity

Amino acid modifications

Glycosylation3621N-linked (GlcNAc...) Potential
Glycosylation8221N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
A7EQZ1 [UniParc].

Last modified September 11, 2007. Version 1.
Checksum: 5425BDA802477FD3

FASTA921103,235
        10         20         30         40         50         60 
MAGHTEENAQ LLSTEQESVS RHSSDSAAST ASTTSLVFDR IGERVAANRS EKSMMVTPKF 

        70         80         90        100        110        120 
PPRGEMAYAD DEHTQIHLDE EEEKDYDLED SAFLTNGATN KSVDKKLRKL IWIVGGVFIG 

       130        140        150        160        170        180 
AWVLALFIFL GKQAYKHSSE IPHDPQATSS RGNGKKVTMD QVMGGQWRAT KHSISWIAGA 

       190        200        210        220        230        240 
NGEDGLLLEQ GSAGKDYLIV EDVRTQNPET VGTLDRMTLM KDGSFTVAGR SLYPSKVYPS 

       250        260        270        280        290        300 
KDLKKVLVAT DVQSNWRHSF YAKYWIFDVE SQTAEPLDPV DLDGRVQLAS WSPKSDAIVF 

       310        320        330        340        350        360 
TRDNNMYLRK LSSPTVIQIT TDGGPEFFYG VPDWVYEEEV FAGASATWWD DSGKYIAFLR 

       370        380        390        400        410        420 
TNESEVPEYP IQYFVSRPSG KEPLPGEENY PEVREIKYPK AGAPNPTVDL LFYDIFKAEV 

       430        440        450        460        470        480 
FEVTIAGGFE PKNLLITEVV WAGSTGKALI RETNRESDIL RVVLVDVVAR EGKTVRYTDI 

       490        500        510        520        530        540 
NKLDGGWFEV SEDTRYIPAD PANGRPHDGY IDTIIHENYD HLGYFTPMDN PEPILLTSGN 

       550        560        570        580        590        600 
WEVVQAPSAV DLKNNLVYFV STKESPITRQ VYSVKLDGTD MKAITDTSNE GYYGASFSKG 

       610        620        630        640        650        660 
AGYVLLNYNG PGIPWQKVIS TPSNGNQYTH TIEENKGLAE MAKKHDLPIL IYQTVTIDGF 

       670        680        690        700        710        720 
ELQVVERRPP HFNPKKKYPV LFYLYGGPGS QTVSKSFNVD FESYIASNLG YIVVTVDGRG 

       730        740        750        760        770        780 
TGFIGRKART IIRGNIGHYE ARDQIETAKI WASKKYVDAS RMAIWGWSYG GFMTLKTLEE 

       790        800        810        820        830        840 
DAGETFSYGM AVAPVTDWRF YDSIYTERYM HTPQHNPGGY DNTSISNVEA LSKNVRFLVM 

       850        860        870        880        890        900 
HGVADDNVHM QNTLTLLDKL DLAGVENYDV HVFPDSDHSI YFHNANRIVY DKLNNWLINA 

       910        920 
FNGEWLRTAN AVPLQIDAAK V 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CH476630 Genomic DNA. Translation: EDN91883.1.
RefSeqXP_001591119.1. XM_001591069.1.

3D structure databases

ProteinModelPortalA7EQZ1.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING665079.A7EQZ1.

Protein family/group databases

MEROPSS09.006.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5487167.
KEGGssl:SS1G_07744.

Phylogenomic databases

eggNOGCOG1506.
KOK01282.
OMAETKFWYQ.
OrthoDBEOG72VHFG.

Family and domain databases

Gene3D2.140.10.30. 1 hit.
InterProIPR001375. Peptidase_S9.
IPR002469. Peptidase_S9B.
[Graphical view]
PfamPF00930. DPPIV_N. 1 hit.
PF00326. Peptidase_S9. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDAPB_SCLS1
AccessionPrimary (citable) accession number: A7EQZ1
Entry history
Integrated into UniProtKB/Swiss-Prot: July 27, 2011
Last sequence update: September 11, 2007
Last modified: April 16, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Peptidase families

Classification of peptidase families and list of entries