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Protein

Hexokinase

Gene

SS1G_05407

Organism
Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1) (White mold) (Whetzelinia sclerotiorum)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-hexose = ADP + D-hexose 6-phosphate.UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. fructokinase activity Source: EnsemblFungi
  3. glucokinase activity Source: EnsemblFungi
  4. mannokinase activity Source: EnsemblFungi

GO - Biological processi

  1. fructose 6-phosphate metabolic process Source: EnsemblFungi
  2. glycolytic fermentation Source: EnsemblFungi
  3. glycolytic process Source: UniProtKB-KW
  4. mannose metabolic process Source: EnsemblFungi
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
HexokinaseUniRule annotation (EC:2.7.1.1UniRule annotation)
Gene namesi
ORF Names:SS1G_05407Imported
OrganismiSclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1) (White mold) (Whetzelinia sclerotiorum)Imported
Taxonomic identifieri665079 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaLeotiomycetesHelotialesSclerotiniaceaeSclerotinia
ProteomesiUP000001312 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:SS1G_05407.

Subcellular locationi

GO - Cellular componenti

  1. cytosol Source: EnsemblFungi
  2. nucleus Source: EnsemblFungi
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi665079.A7EJB4.

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG5026.
InParanoidiA7EJB4.
KOiK00844.
OMAiIRRRNTV.
OrthoDBiEOG79SF68.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 2 hits.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A7EJB4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLLAESKRV AAEFEYSDED VRRGVAEFIA EMNEGLEKNA TNMSQIPTYV
60 70 80 90 100
TGVPNGTEKG LYLAVDLGGT NFRVCSIQLH GDTTFSLTQS KVAIPRELML
110 120 130 140 150
AKTASDLFSF LAKQIELFLK THHEDHFAAH IRRRNTVSTP EGFRDEHIFR
160 170 180 190 200
LGFTFSFPVH QIGINRGTLI RWTKGFDIAD AVGQDVCELL QKEIDKLHLP
210 220 230 240 250
VKVAALVNDT VGTLMARAYT SPGKAQTVLG AIFGTGTNGA YVEKLEKLTK
260 270 280 290 300
PMEGDFDKTT GEMVVNTEWG SFDNGLKVLP NTIYDQILDK DSVNPGIQMF
310 320 330 340 350
EKRVSGMFLG EILRTTLIEM MKSPISTLFK DKSSADNDYR STTNIDENGA
360 370 380 390 400
LFKQWAVDSS ILSIAEADNS IGLRALRQEL EKSLGVSAAS LEDAQTVKEI
410 420 430 440 450
AHAIGKRAAR LAAVAIGAVV LHTGRLDNIS DANKPKSTTS IVQDVQDLKL
460 470 480 490 500
ADAASATASK LADTAGLKIN EEDIIDIGVD GSLVEFYPGF EEYMREALRA
510 520 530 540 550
MDGIGAAGER RIRIGIAKDG SGVGAALIAL VAAGMEKQQD YIGDLRSKYG

AIAE
Length:554
Mass (Da):60,195
Last modified:September 11, 2007 - v1
Checksum:i333041BC5A3EB406
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH476626 Genomic DNA. Translation: EDO02930.1.
RefSeqiXP_001593979.1. XM_001593929.1.

Genome annotation databases

EnsemblFungiiEDO02930; EDO02930; SS1G_05407.
GeneIDi5490348.
KEGGissl:SS1G_05407.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH476626 Genomic DNA. Translation: EDO02930.1.
RefSeqiXP_001593979.1. XM_001593929.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi665079.A7EJB4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiEDO02930; EDO02930; SS1G_05407.
GeneIDi5490348.
KEGGissl:SS1G_05407.

Organism-specific databases

EuPathDBiFungiDB:SS1G_05407.

Phylogenomic databases

eggNOGiCOG5026.
InParanoidiA7EJB4.
KOiK00844.
OMAiIRRRNTV.
OrthoDBiEOG79SF68.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 2 hits.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genomic analysis of the necrotrophic fungal pathogens Sclerotinia sclerotiorum and Botrytis cinerea."
    Amselem J., Cuomo C.A., van Kan J.A.L., Viaud M., Benito E.P., Couloux A., Coutinho P.M., de Vries R.P., Dyer P.S., Fillinger S., Fournier E., Gout L., Hahn M., Kohn L., Lapalu N., Plummer K.M., Pradier J.-M., Quevillon E.
    , Sharon A., Simon A., ten Have A., Tudzynski B., Tudzynski P., Wincker P., Andrew M., Anthouard V., Beever R.E., Beffa R., Benoit I., Bouzid O., Brault B., Chen Z., Choquer M., Collemare J., Cotton P., Danchin E.G., Da Silva C., Gautier A., Giraud C., Giraud T., Gonzalez C., Grossetete S., Gueldener U., Henrissat B., Howlett B.J., Kodira C., Kretschmer M., Lappartient A., Leroch M., Levis C., Mauceli E., Neuveglise C., Oeser B., Pearson M., Poulain J., Poussereau N., Quesneville H., Rascle C., Schumacher J., Segurens B., Sexton A., Silva E., Sirven C., Soanes D.M., Talbot N.J., Templeton M., Yandava C., Yarden O., Zeng Q., Rollins J.A., Lebrun M.-H., Dickman M.
    PLoS Genet. 7:E1002230-E1002230(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 18683 / 1980 / Ss-1Imported.

Entry informationi

Entry nameiA7EJB4_SCLS1
AccessioniPrimary (citable) accession number: A7EJB4
Entry historyi
Integrated into UniProtKB/TrEMBL: September 11, 2007
Last sequence update: September 11, 2007
Last modified: April 29, 2015
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.