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A7E3U5

- S38A7_BOVIN

UniProt

A7E3U5 - S38A7_BOVIN

Protein

Putative sodium-coupled neutral amino acid transporter 7

Gene

SLC38A7

Organism
Bos taurus (Bovine)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 48 (01 Oct 2014)
      Sequence version 1 (11 Sep 2007)
      Previous versions | rss
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    Functioni

    Mediates sodium-dependent transport of amino acids, preferentially L-glutamine.By similarity

    GO - Molecular functioni

    1. L-alanine transmembrane transporter activity Source: Ensembl
    2. L-amino acid transmembrane transporter activity Source: UniProtKB
    3. L-asparagine transmembrane transporter activity Source: Ensembl
    4. L-aspartate transmembrane transporter activity Source: Ensembl
    5. L-glutamate transmembrane transporter activity Source: Ensembl
    6. L-glutamine transmembrane transporter activity Source: UniProtKB
    7. L-histidine transmembrane transporter activity Source: Ensembl
    8. L-leucine transmembrane transporter activity Source: Ensembl
    9. L-methionine transmembrane transporter activity Source: Ensembl
    10. L-serine transmembrane transporter activity Source: Ensembl

    GO - Biological processi

    1. L-alpha-amino acid transmembrane transport Source: GOC
    2. sodium ion transport Source: UniProtKB

    Keywords - Biological processi

    Amino-acid transport, Ion transport, Sodium transport, Transport

    Keywords - Ligandi

    Sodium

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative sodium-coupled neutral amino acid transporter 7
    Alternative name(s):
    Solute carrier family 38 member 7
    Gene namesi
    Name:SLC38A7
    Synonyms:SNAT7
    OrganismiBos taurus (Bovine)
    Taxonomic identifieri9913 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
    ProteomesiUP000009136: Chromosome 18

    Subcellular locationi

    Membrane By similarity; Multi-pass membrane protein By similarity
    Note: In neurons, located in soma and axons.By similarity

    GO - Cellular componenti

    1. axon Source: UniProtKB
    2. integral component of membrane Source: UniProtKB-KW
    3. neuronal cell body Source: UniProtKB

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 463463Putative sodium-coupled neutral amino acid transporter 7PRO_0000319596Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi9913.ENSBTAP00000009438.

    Structurei

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei56 – 7621HelicalSequence AnalysisAdd
    BLAST
    Transmembranei82 – 10221HelicalSequence AnalysisAdd
    BLAST
    Transmembranei130 – 15021HelicalSequence AnalysisAdd
    BLAST
    Transmembranei179 – 19921HelicalSequence AnalysisAdd
    BLAST
    Transmembranei206 – 22621HelicalSequence AnalysisAdd
    BLAST
    Transmembranei240 – 26021HelicalSequence AnalysisAdd
    BLAST
    Transmembranei283 – 30321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei320 – 34021HelicalSequence AnalysisAdd
    BLAST
    Transmembranei372 – 39221HelicalSequence AnalysisAdd
    BLAST
    Transmembranei396 – 41621HelicalSequence AnalysisAdd
    BLAST
    Transmembranei429 – 44921HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG0814.
    GeneTreeiENSGT00710000106751.
    HOGENOMiHOG000008036.
    HOVERGENiHBG055999.
    InParanoidiA7E3U5.
    KOiK14994.
    OMAiTWGGVVT.
    OrthoDBiEOG769ZJG.
    TreeFamiTF328787.

    Family and domain databases

    InterProiIPR013057. AA_transpt_TM.
    [Graphical view]
    PfamiPF01490. Aa_trans. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A7E3U5-1 [UniParc]FASTAAdd to Basket

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    MAQVSINRDL GEWGLSTDSG ERARLLQSPS VDIAPKSEGE APPGGVGGGT    50
    TSTLGAIFIV VNACLGAGLL NFPAAFSTAG GVAAGITLQM AMLVFIISGL 100
    VILAYCSQAS NERTYQEVVW AVCGKLTGVL CEVAIATYTF GTCIAFLIII 150
    GDQQDKIIAV MAKEPEGPGG SPWYTDRKFT ISLTAFLFIL PLSIPREIGF 200
    QKYASFLSVV GTWYVTAIII IKYIWPDKEM TPADILNRPA SWIAVFNAMP 250
    TICFGFQCHV SSVPVFNSMR QPEVKTWGGV VTAAMVIALA VYMGTGICGF 300
    LTFGDAVDPD VLLSYPSEDM AVAVARAFII LSVLTSYPIL HFCGRAVIEG 350
    LWLRYQGMPV EEDVGRERRR RVLQTLVWFL LTLLLALFIP DIGKVISVIG 400
    GLAACFIFVF PGLCLIQAKL SEMEEVKPAS WWAMVSYGVL LVTLGAFIFG 450
    QTTANAIFVD LLA 463
    Length:463
    Mass (Da):49,853
    Last modified:September 11, 2007 - v1
    Checksum:iC0929D8494FAA397
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BT030716 mRNA. Translation: ABS45032.1.
    RefSeqiNP_001093825.1. NM_001100355.1.
    XP_005218601.1. XM_005218544.1.
    XP_005218602.1. XM_005218545.1.
    UniGeneiBt.53312.

    Genome annotation databases

    EnsembliENSBTAT00000009438; ENSBTAP00000009438; ENSBTAG00000007170.
    GeneIDi513110.
    KEGGibta:513110.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BT030716 mRNA. Translation: ABS45032.1 .
    RefSeqi NP_001093825.1. NM_001100355.1.
    XP_005218601.1. XM_005218544.1.
    XP_005218602.1. XM_005218545.1.
    UniGenei Bt.53312.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 9913.ENSBTAP00000009438.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSBTAT00000009438 ; ENSBTAP00000009438 ; ENSBTAG00000007170 .
    GeneIDi 513110.
    KEGGi bta:513110.

    Organism-specific databases

    CTDi 55238.

    Phylogenomic databases

    eggNOGi COG0814.
    GeneTreei ENSGT00710000106751.
    HOGENOMi HOG000008036.
    HOVERGENi HBG055999.
    InParanoidi A7E3U5.
    KOi K14994.
    OMAi TWGGVVT.
    OrthoDBi EOG769ZJG.
    TreeFami TF328787.

    Miscellaneous databases

    NextBioi 20870706.

    Family and domain databases

    InterProi IPR013057. AA_transpt_TM.
    [Graphical view ]
    Pfami PF01490. Aa_trans. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

    Entry informationi

    Entry nameiS38A7_BOVIN
    AccessioniPrimary (citable) accession number: A7E3U5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 26, 2008
    Last sequence update: September 11, 2007
    Last modified: October 1, 2014
    This is version 48 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3