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Protein

Putative sodium-coupled neutral amino acid transporter 7

Gene

SLC38A7

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

Mediates sodium-dependent transport of amino acids, preferentially L-glutamine.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Amino-acid transport, Ion transport, Sodium transport, Transport

Keywords - Ligandi

Sodium

Names & Taxonomyi

Protein namesi
Recommended name:
Putative sodium-coupled neutral amino acid transporter 7
Alternative name(s):
Solute carrier family 38 member 7
Gene namesi
Name:SLC38A7
Synonyms:SNAT7
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 18

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei56 – 76HelicalSequence analysisAdd BLAST21
Transmembranei82 – 102HelicalSequence analysisAdd BLAST21
Transmembranei130 – 150HelicalSequence analysisAdd BLAST21
Transmembranei179 – 199HelicalSequence analysisAdd BLAST21
Transmembranei206 – 226HelicalSequence analysisAdd BLAST21
Transmembranei240 – 260HelicalSequence analysisAdd BLAST21
Transmembranei283 – 303HelicalSequence analysisAdd BLAST21
Transmembranei320 – 340HelicalSequence analysisAdd BLAST21
Transmembranei372 – 392HelicalSequence analysisAdd BLAST21
Transmembranei396 – 416HelicalSequence analysisAdd BLAST21
Transmembranei429 – 449HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003195961 – 463Putative sodium-coupled neutral amino acid transporter 7Add BLAST463

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei28PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiA7E3U5.

Expressioni

Gene expression databases

BgeeiENSBTAG00000007170.

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000009438.

Structurei

3D structure databases

ProteinModelPortaliA7E3U5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG1305. Eukaryota.
COG0814. LUCA.
GeneTreeiENSGT00710000106751.
HOGENOMiHOG000008036.
HOVERGENiHBG055999.
InParanoidiA7E3U5.
KOiK14994.
OMAiSWVAVFN.
OrthoDBiEOG091G08A4.
TreeFamiTF328787.

Family and domain databases

InterProiIPR013057. AA_transpt_TM.
[Graphical view]
PfamiPF01490. Aa_trans. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A7E3U5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQVSINRDL GEWGLSTDSG ERARLLQSPS VDIAPKSEGE APPGGVGGGT
60 70 80 90 100
TSTLGAIFIV VNACLGAGLL NFPAAFSTAG GVAAGITLQM AMLVFIISGL
110 120 130 140 150
VILAYCSQAS NERTYQEVVW AVCGKLTGVL CEVAIATYTF GTCIAFLIII
160 170 180 190 200
GDQQDKIIAV MAKEPEGPGG SPWYTDRKFT ISLTAFLFIL PLSIPREIGF
210 220 230 240 250
QKYASFLSVV GTWYVTAIII IKYIWPDKEM TPADILNRPA SWIAVFNAMP
260 270 280 290 300
TICFGFQCHV SSVPVFNSMR QPEVKTWGGV VTAAMVIALA VYMGTGICGF
310 320 330 340 350
LTFGDAVDPD VLLSYPSEDM AVAVARAFII LSVLTSYPIL HFCGRAVIEG
360 370 380 390 400
LWLRYQGMPV EEDVGRERRR RVLQTLVWFL LTLLLALFIP DIGKVISVIG
410 420 430 440 450
GLAACFIFVF PGLCLIQAKL SEMEEVKPAS WWAMVSYGVL LVTLGAFIFG
460
QTTANAIFVD LLA
Length:463
Mass (Da):49,853
Last modified:September 11, 2007 - v1
Checksum:iC0929D8494FAA397
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT030716 mRNA. Translation: ABS45032.1.
RefSeqiNP_001093825.1. NM_001100355.1.
XP_005218601.1. XM_005218544.3.
XP_015331219.1. XM_015475733.1.
UniGeneiBt.53312.

Genome annotation databases

EnsembliENSBTAT00000009438; ENSBTAP00000009438; ENSBTAG00000007170.
GeneIDi513110.
KEGGibta:513110.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT030716 mRNA. Translation: ABS45032.1.
RefSeqiNP_001093825.1. NM_001100355.1.
XP_005218601.1. XM_005218544.3.
XP_015331219.1. XM_015475733.1.
UniGeneiBt.53312.

3D structure databases

ProteinModelPortaliA7E3U5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000009438.

Proteomic databases

PaxDbiA7E3U5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSBTAT00000009438; ENSBTAP00000009438; ENSBTAG00000007170.
GeneIDi513110.
KEGGibta:513110.

Organism-specific databases

CTDi55238.

Phylogenomic databases

eggNOGiKOG1305. Eukaryota.
COG0814. LUCA.
GeneTreeiENSGT00710000106751.
HOGENOMiHOG000008036.
HOVERGENiHBG055999.
InParanoidiA7E3U5.
KOiK14994.
OMAiSWVAVFN.
OrthoDBiEOG091G08A4.
TreeFamiTF328787.

Gene expression databases

BgeeiENSBTAG00000007170.

Family and domain databases

InterProiIPR013057. AA_transpt_TM.
[Graphical view]
PfamiPF01490. Aa_trans. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiS38A7_BOVIN
AccessioniPrimary (citable) accession number: A7E3U5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: September 11, 2007
Last modified: November 2, 2016
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.