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A7E3U5

- S38A7_BOVIN

UniProt

A7E3U5 - S38A7_BOVIN

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Protein
Putative sodium-coupled neutral amino acid transporter 7
Gene
SLC38A7, SNAT7
Organism
Bos taurus (Bovine)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

Mediates sodium-dependent transport of amino acids, preferentially L-glutamine By similarity.

GO - Molecular functioni

  1. L-alanine transmembrane transporter activity Source: Ensembl
  2. L-amino acid transmembrane transporter activity Source: UniProtKB
  3. L-asparagine transmembrane transporter activity Source: Ensembl
  4. L-aspartate transmembrane transporter activity Source: Ensembl
  5. L-glutamate transmembrane transporter activity Source: Ensembl
  6. L-glutamine transmembrane transporter activity Source: UniProtKB
  7. L-histidine transmembrane transporter activity Source: Ensembl
  8. L-leucine transmembrane transporter activity Source: Ensembl
  9. L-methionine transmembrane transporter activity Source: Ensembl
  10. L-serine transmembrane transporter activity Source: Ensembl

GO - Biological processi

  1. L-alpha-amino acid transmembrane transport Source: GOC
  2. sodium ion transport Source: UniProtKB
Complete GO annotation...

Keywords - Biological processi

Amino-acid transport, Ion transport, Sodium transport, Transport

Keywords - Ligandi

Sodium

Names & Taxonomyi

Protein namesi
Recommended name:
Putative sodium-coupled neutral amino acid transporter 7
Alternative name(s):
Solute carrier family 38 member 7
Gene namesi
Name:SLC38A7
Synonyms:SNAT7
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
ProteomesiUP000009136: Chromosome 18

Subcellular locationi

Membrane; Multi-pass membrane protein By similarity
Note: In neurons, located in soma and axons By similarity.

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei56 – 7621Helical; Reviewed prediction
Add
BLAST
Transmembranei82 – 10221Helical; Reviewed prediction
Add
BLAST
Transmembranei130 – 15021Helical; Reviewed prediction
Add
BLAST
Transmembranei179 – 19921Helical; Reviewed prediction
Add
BLAST
Transmembranei206 – 22621Helical; Reviewed prediction
Add
BLAST
Transmembranei240 – 26021Helical; Reviewed prediction
Add
BLAST
Transmembranei283 – 30321Helical; Reviewed prediction
Add
BLAST
Transmembranei320 – 34021Helical; Reviewed prediction
Add
BLAST
Transmembranei372 – 39221Helical; Reviewed prediction
Add
BLAST
Transmembranei396 – 41621Helical; Reviewed prediction
Add
BLAST
Transmembranei429 – 44921Helical; Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. axon Source: UniProtKB
  2. integral component of membrane Source: UniProtKB-KW
  3. neuronal cell body Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 463463Putative sodium-coupled neutral amino acid transporter 7
PRO_0000319596Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000009438.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0814.
GeneTreeiENSGT00710000106751.
HOGENOMiHOG000008036.
HOVERGENiHBG055999.
InParanoidiA7E3U5.
KOiK14994.
OMAiTWGGVVT.
OrthoDBiEOG769ZJG.
TreeFamiTF328787.

Family and domain databases

InterProiIPR013057. AA_transpt_TM.
[Graphical view]
PfamiPF01490. Aa_trans. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A7E3U5-1 [UniParc]FASTAAdd to Basket

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MAQVSINRDL GEWGLSTDSG ERARLLQSPS VDIAPKSEGE APPGGVGGGT    50
TSTLGAIFIV VNACLGAGLL NFPAAFSTAG GVAAGITLQM AMLVFIISGL 100
VILAYCSQAS NERTYQEVVW AVCGKLTGVL CEVAIATYTF GTCIAFLIII 150
GDQQDKIIAV MAKEPEGPGG SPWYTDRKFT ISLTAFLFIL PLSIPREIGF 200
QKYASFLSVV GTWYVTAIII IKYIWPDKEM TPADILNRPA SWIAVFNAMP 250
TICFGFQCHV SSVPVFNSMR QPEVKTWGGV VTAAMVIALA VYMGTGICGF 300
LTFGDAVDPD VLLSYPSEDM AVAVARAFII LSVLTSYPIL HFCGRAVIEG 350
LWLRYQGMPV EEDVGRERRR RVLQTLVWFL LTLLLALFIP DIGKVISVIG 400
GLAACFIFVF PGLCLIQAKL SEMEEVKPAS WWAMVSYGVL LVTLGAFIFG 450
QTTANAIFVD LLA 463
Length:463
Mass (Da):49,853
Last modified:September 11, 2007 - v1
Checksum:iC0929D8494FAA397
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BT030716 mRNA. Translation: ABS45032.1.
RefSeqiNP_001093825.1. NM_001100355.1.
XP_005218601.1. XM_005218544.1.
XP_005218602.1. XM_005218545.1.
UniGeneiBt.53312.

Genome annotation databases

EnsembliENSBTAT00000009438; ENSBTAP00000009438; ENSBTAG00000007170.
GeneIDi513110.
KEGGibta:513110.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BT030716 mRNA. Translation: ABS45032.1 .
RefSeqi NP_001093825.1. NM_001100355.1.
XP_005218601.1. XM_005218544.1.
XP_005218602.1. XM_005218545.1.
UniGenei Bt.53312.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 9913.ENSBTAP00000009438.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSBTAT00000009438 ; ENSBTAP00000009438 ; ENSBTAG00000007170 .
GeneIDi 513110.
KEGGi bta:513110.

Organism-specific databases

CTDi 55238.

Phylogenomic databases

eggNOGi COG0814.
GeneTreei ENSGT00710000106751.
HOGENOMi HOG000008036.
HOVERGENi HBG055999.
InParanoidi A7E3U5.
KOi K14994.
OMAi TWGGVVT.
OrthoDBi EOG769ZJG.
TreeFami TF328787.

Miscellaneous databases

NextBioi 20870706.

Family and domain databases

InterProi IPR013057. AA_transpt_TM.
[Graphical view ]
Pfami PF01490. Aa_trans. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

Entry informationi

Entry nameiS38A7_BOVIN
AccessioniPrimary (citable) accession number: A7E3U5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: September 11, 2007
Last modified: April 16, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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