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Protein
Submitted name:

CAP-GLY domain containing linker protein 2

Gene

CLIP2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
CAP-GLY domain containing linker protein 2Imported
Submitted name:
Cytoplasmic linker 2, isoform CRA_aImported
Gene namesi
Name:CLIP2Imported
Synonyms:CYLN2Imported
ORF Names:hCG_18038Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA27085.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000223398.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini99 – 141CAP-GlyInterPro annotationAdd BLAST43
Domaini239 – 281CAP-GlyInterPro annotationAdd BLAST43

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili354 – 381Sequence analysisAdd BLAST28
Coiled coili396 – 455Sequence analysisAdd BLAST60
Coiled coili529 – 577Sequence analysisAdd BLAST49
Coiled coili640 – 667Sequence analysisAdd BLAST28
Coiled coili669 – 765Sequence analysisAdd BLAST97
Coiled coili818 – 852Sequence analysisAdd BLAST35
Coiled coili901 – 928Sequence analysisAdd BLAST28
Coiled coili948 – 975Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG4568. Eukaryota.
COG5244. LUCA.
HOGENOMiHOG000092755.
HOVERGENiHBG007123.

Family and domain databases

Gene3Di2.30.30.190. 2 hits.
InterProiIPR000938. CAP-Gly_domain.
IPR028394. CLIP2.
[Graphical view]
PANTHERiPTHR18916:SF10. PTHR18916:SF10. 1 hit.
PfamiPF01302. CAP_GLY. 2 hits.
[Graphical view]
SMARTiSM01052. CAP_GLY. 2 hits.
[Graphical view]
SUPFAMiSSF74924. SSF74924. 2 hits.
PROSITEiPS00845. CAP_GLY_1. 2 hits.
PS50245. CAP_GLY_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A7E2F7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQKPSGLKPP GRGGKHSSPM GRTSTGSASS SAAVAASSKE GSPLHKQSSG
60 70 80 90 100
PSSSPAAAAA PEKPGPKAAE VGDDFLGDFV VGERVWVNGV KPGVVQYLGE
110 120 130 140 150
TQFAPGQWAG VVLDDPVGKN DGAVGGVRYF ECPALQGIFT RPSKLTRQPT
160 170 180 190 200
AEGSGSDAHS VESLTAQNLS LHSGTATPPL TSRVIPLRES VLNSSVKTGN
210 220 230 240 250
ESGSNLSDSG SVKRGEKDLR LGDRVLVGGT KTGVVRYVGE TDFAKGEWCG
260 270 280 290 300
VELDEPLGKN DGAVAGTRYF QCPPKFGLFA PIHKVIRIGF PSTSPAKAKK
310 320 330 340 350
TKRMAMGVSA LTHSPSSSSI SSVSSVASSV GGRPSRSGLL TETSSRYARK
360 370 380 390 400
ISGTTALQEA LKEKQQHIEQ LLAERDLERA EVAKATSHIC EVEKEIALLK
410 420 430 440 450
AQHEQYVAEA EEKLQRARLL VESVRKEKVD LSNQLEEERR KVEDLQFRVE
460 470 480 490 500
EESITKGDLE LTTVAEKSRV LQLEEELTLR RGEIEELQQC LLHSGPPPPD
510 520 530 540 550
HPDAAEILRL RERLLSASKE HQRESGVLRD KYEKALKAYQ AEVDKLRAAN
560 570 580 590 600
EKYAQEVAGL KDKVQQATSE NMGLMDNWKS KLDSLASDHQ KSLEDLKATL
610 620 630 640 650
NSGPGAQQKE IGELKAVMEG IKMEHQLELG NLQAKHDLET AMHVKEKEAL
660 670 680 690 700
REKLQEAQEE LAGLQRHWRA QLEVQASQHR LELQEAQDQR RDAELRVHEL
710 720 730 740 750
EKLDVEYRGQ AQAIEFLKEQ ISLAEKKMLD YERLQRAEAQ GKQEVESLRE
760 770 780 790 800
KLLVAENRLQ AVEALCSSQH THMIESNDIS EETIRTKETV EGLQDKLNKR
810 820 830 840 850
DKEVTALTSQ TEMLRAQVSA LESKCKSGEK KVDALLKEKR RLEAELETVS
860 870 880 890 900
RKTHDASGQL VLISQELLRK ERSLNELRVL LLEANRHSPG PERDLSREVH
910 920 930 940 950
KAEWRIKEQK LKDDIRGLRE KLTGLDKEKS LSDQRRYSLI DPSSAPELLR
960 970 980 990 1000
LQHQLMSTED ALRDALDQAQ QVEKLMEAMR SCPDKAQTIG NSGSANGIHQ
1010
QDKAQKQEDK H
Length:1,011
Mass (Da):111,723
Last modified:September 11, 2007 - v1
Checksum:i2E745BB10115487C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC150332 mRNA. Translation: AAI50333.1.
CH471200 Genomic DNA. Translation: EAW69603.1.
RefSeqiNP_115797.1. NM_032421.2.
UniGeneiHs.647018.

Genome annotation databases

GeneIDi7461.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC150332 mRNA. Translation: AAI50333.1.
CH471200 Genomic DNA. Translation: EAW69603.1.
RefSeqiNP_115797.1. NM_032421.2.
UniGeneiHs.647018.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000223398.

Protocols and materials databases

DNASUi7461.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi7461.

Organism-specific databases

CTDi7461.
PharmGKBiPA27085.

Phylogenomic databases

eggNOGiKOG4568. Eukaryota.
COG5244. LUCA.
HOGENOMiHOG000092755.
HOVERGENiHBG007123.

Miscellaneous databases

ChiTaRSiCLIP2. human.
GenomeRNAii7461.

Family and domain databases

Gene3Di2.30.30.190. 2 hits.
InterProiIPR000938. CAP-Gly_domain.
IPR028394. CLIP2.
[Graphical view]
PANTHERiPTHR18916:SF10. PTHR18916:SF10. 1 hit.
PfamiPF01302. CAP_GLY. 2 hits.
[Graphical view]
SMARTiSM01052. CAP_GLY. 2 hits.
[Graphical view]
SUPFAMiSSF74924. SSF74924. 2 hits.
PROSITEiPS00845. CAP_GLY_1. 2 hits.
PS50245. CAP_GLY_2. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA7E2F7_HUMAN
AccessioniPrimary (citable) accession number: A7E2F7
Entry historyi
Integrated into UniProtKB/TrEMBL: September 11, 2007
Last sequence update: September 11, 2007
Last modified: November 30, 2016
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.