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Protein
Submitted name:

CACNA2D4 protein

Gene

CACNA2D4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
CACNA2D4 proteinImported
Gene namesi
Name:CACNA2D4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PaxDbiA7E243.
PeptideAtlasiA7E243.
PRIDEiA7E243.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000372169.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini291 – 473VWFAInterPro annotationAdd BLAST183

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili130 – 151Sequence analysisAdd BLAST22

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG2353. Eukaryota.
ENOG410XPDX. LUCA.
HOGENOMiHOG000170681.

Family and domain databases

Gene3Di3.40.50.410. 1 hit.
InterProiIPR013608. VWA_N.
IPR002035. VWF_A.
[Graphical view]
PfamiPF13768. VWA_3. 1 hit.
PF08399. VWA_N. 1 hit.
[Graphical view]
SMARTiSM00327. VWA. 1 hit.
[Graphical view]
SUPFAMiSSF53300. SSF53300. 1 hit.
PROSITEiPS50234. VWFA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A7E243-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVCGCSALLP LPNPRPTMPA TPNFLANPSS SSRWIPLQPM PVAWAFVQKT
60 70 80 90 100
SALLWLLLLG TSLSPAWGQA KIPLETVKLW ADTFGGDLYN TVTKYSGSLL
110 120 130 140 150
LQKKYKDVES SLKIEEVDGL ELVRKFSEDM ENMLRRKVEA VQNLVEAAEE
160 170 180 190 200
ADLNHEFNES LVFDYYNSVL INERDEKGNF VELGAEFLLE SNAHFSNLPV
210 220 230 240 250
NTSISSVQLP TNVYNKDPDI LNGVYMSEAL NAVFVENFQR DPTLTWQYFG
260 270 280 290 300
SATGFFRIYP GIKWTPDENG VITFDCRNRG WYIQAATSPK DIVILVDVSG
310 320 330 340 350
SMKGLRMTIA KHTITTILDT LGENDFVNII AYNDYVHYIE PCFKGILVQA
360 370 380 390 400
DRDNREHFKL LVEELMVKGV GVVDQALREA FQILKQFQEA KQGSLCNQAI
410 420 430 440 450
MLISDGAVED YEPVFEKYNW PDCKVRVFTY LIGREVSFAD RMKWIACNNK
460 470 480 490 500
GYYTQISTLA DTQENVMEYL HVLSRPMVIN HDHDIIWTEA YMDSKLLSSQ
510 520 530 540 550
AQSLTLLTTV AMPVFSKKNE TRSHGILLGV VGSDVALREL MKLAPRYKMP
560 570 580 590 600
STNSRPNAPP PWTLAAWSAR IRLSEHQQWL HPLPSRPPAP VQRGEETKTQ

T
Length:601
Mass (Da):68,012
Last modified:September 11, 2007 - v1
Checksum:iB3A0999D2B7A1164
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC150186 mRNA. Translation: AAI50187.1.
UniGeneiHs.13768.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC150186 mRNA. Translation: AAI50187.1.
UniGeneiHs.13768.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000372169.

Proteomic databases

PaxDbiA7E243.
PeptideAtlasiA7E243.
PRIDEiA7E243.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG2353. Eukaryota.
ENOG410XPDX. LUCA.
HOGENOMiHOG000170681.

Miscellaneous databases

ChiTaRSiCACNA2D4. human.

Family and domain databases

Gene3Di3.40.50.410. 1 hit.
InterProiIPR013608. VWA_N.
IPR002035. VWF_A.
[Graphical view]
PfamiPF13768. VWA_3. 1 hit.
PF08399. VWA_N. 1 hit.
[Graphical view]
SMARTiSM00327. VWA. 1 hit.
[Graphical view]
SUPFAMiSSF53300. SSF53300. 1 hit.
PROSITEiPS50234. VWFA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA7E243_HUMAN
AccessioniPrimary (citable) accession number: A7E243
Entry historyi
Integrated into UniProtKB/TrEMBL: September 11, 2007
Last sequence update: September 11, 2007
Last modified: July 6, 2016
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.