A7E220 (A7E220_DANRE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Glial cell derived neurotrophic factor EMBL AAI50164.1

Submitted name:
Glial cell line-derived neurotrophic factor Ensembl ENSDARP00000124666
Submitted name:
Uncharacterized protein Ensembl ENSDARP00000058462

Gene names

Name:	gdnfa ZFIN ZDB-GENE-010226-1 Ensembl ENSDARP00000124666 Ensembl ENSDARP00000058462
Synonyms:	gdnf ZFIN ZDB-GENE-010226-1 Ensembl ENSDARP00000124666 EMBL AAI50164.1

Organism

Danio rerio (Zebrafish) (Brachydanio rerio) [Reference proteome]

Taxonomic identifier

7955 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Actinopterygii › Actinopteri › Neopterygii › Teleostei › Elopocephala › Clupeocephala › Otocephala › Ostariophysi › Otophysi › Cypriniphysi › Cypriniformes › Cyprinoidea › Cyprinidae › Danio

Protein attributes

Sequence length	235 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the TGF-beta family. RuleBase RU000354

Ontologies

Keywords
Cellular component	Secreted SAAS SAAS001839
Molecular function	Growth factor SAAS SAAS001839 RuleBase RU000354
PTM	Disulfide bond SAAS SAAS001839
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	extracellular region Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A7E220 [UniParc]. Last modified September 11, 2007. Version 1. Checksum: E5911FD8DD55F329	FASTA	235	26,906
	10 20 30 40 50 60 MKLWDILATC LLLLSSVSTR PLFHKLQPSK RAVVRSESPA LDPIIDSQPE TSNPKQASME 70 80 90 100 110 120 EQYDLTGLYP EQFEDVMDFI EATLGRLRRS SDVEPQMKRD RVRQKAAANT EKYGGRGRGE 130 140 150 160 170 180 RKRSRGRARS RDDRVKGQGR GCLLKEIHLN VTDLDLGYRT KEELIFRYCS GPCHDAETNY 190 200 210 220 230 DKILNNLTHN KKLDKDTPSR TCCRPIAFDD DISFLDDSLE YHTLKKHSAK KCACV

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	NIH - Zebrafish Gene Collection (ZGC) project Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Embryo EMBL AAI50164.1.
[2]	"The genomic sequence of Danio rerio." The Danio rerio Sequencing Project at the Sanger Institute Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Tuebingen Ensembl ENSDARP00000124666.
[3]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: Tuebingen Ensembl ENSDARP00000124666.
[4]	Ensembl Submitted (AUG-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: Tuebingen Ensembl ENSDARP00000124666 Ensembl ENSDARP00000058462.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU914630 Genomic DNA. No translation available. CU928210 Genomic DNA. No translation available. BC150163 mRNA. Translation: AAI50164.1.
IPI	IPI00499268.
UniGene	Dr.11721.
3D structure databases
SMR	A7E220. Positions 141-235.
ModBase	Search...
Protein-protein interaction databases
STRING	7955.ENSDARP00000058462.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSDART00000058463; ENSDARP00000058462; ENSDARG00000039959. ENSDART00000150096; ENSDARP00000124666; ENSDARG00000039959.
Organism-specific databases
ZFIN	ZDB-GENE-010226-1. gdnfa.
Phylogenomic databases
GeneTree	ENSGT00520000055559.
HOVERGEN	HBG106680.
Family and domain databases
InterPro	IPR016649. GDNF. IPR001839. TGF-b_C. [Graphical view]
Pfam	PF00019. TGF_beta. 1 hit. [Graphical view]
PIRSF	PIRSF016238. GDNF. 1 hit.
PROSITE	PS51362. TGF_BETA_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A7E220_DANRE

Accession

Primary (citable) accession number: A7E220

Entry history

Integrated into UniProtKB/TrEMBL:	September 11, 2007
Last sequence update:	September 11, 2007
Last modified:	April 3, 2013
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)