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A7E0V8

- A7E0V8_HUMAN

UniProt

A7E0V8 - A7E0V8_HUMAN

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Protein
Submitted name: MHC class II antigen
Gene
HLA-D
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein predictedi

Functioni

GO - Biological processi

  1. antigen processing and presentation of peptide or polysaccharide antigen via MHC class II Source: UniProtKB-KW
  2. immune response Source: InterPro
Complete GO annotation...

Keywords - Biological processi

Immunity

Names & Taxonomyi

Protein namesi
Submitted name:
MHC class II antigenImported
Gene namesi
Name:HLA-DImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. MHC class II protein complex Source: UniProtKB-KW
  2. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane, MHC IIUniRule annotation

PTM / Processingi

Proteomic databases

PRIDEiA7E0V8.

Structurei

3D structure databases

ProteinModelPortaliA7E0V8.

Family & Domainsi

Keywords - Domaini

TransmembraneUniRule annotation

Family and domain databases

Gene3Di3.10.320.10. 1 hit.
InterProiIPR011162. MHC_I/II-like_Ag-recog.
IPR014745. MHC_II_a/b_N.
IPR000353. MHC_II_b_N.
[Graphical view]
PfamiPF00969. MHC_II_beta. 1 hit.
[Graphical view]
ProDomiPD000328. MHC_II_b_N. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTiSM00921. MHC_II_beta. 1 hit.
[Graphical view]
SUPFAMiSSF54452. SSF54452. 1 hit.

Sequencei

Sequence statusi: Fragment.

A7E0V8-1 [UniParc]FASTAAdd to Basket

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RFLEYSTSEC HFFNGTERVR YLDRYFHNQE ENVRFDSDVG EFRAVTELGR   50
PDAEYWNSQK DLLEQKRGRV DNYCRHNYGV VESFTVQRR 89
Length:89
Mass (Da):10,864
Last modified:September 11, 2007 - v1
Checksum:i3ECCE64964BA134B
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei89 – 891Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM777659 Genomic DNA. Translation: CAO82436.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM777659 Genomic DNA. Translation: CAO82436.1 .

3D structure databases

ProteinModelPortali A7E0V8.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi A7E0V8.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Miscellaneous databases

NextBioi 35463233.

Family and domain databases

Gene3Di 3.10.320.10. 1 hit.
InterProi IPR011162. MHC_I/II-like_Ag-recog.
IPR014745. MHC_II_a/b_N.
IPR000353. MHC_II_b_N.
[Graphical view ]
Pfami PF00969. MHC_II_beta. 1 hit.
[Graphical view ]
ProDomi PD000328. MHC_II_b_N. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
SMARTi SM00921. MHC_II_beta. 1 hit.
[Graphical view ]
SUPFAMi SSF54452. SSF54452. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Searching for species in haloarchaea."
    Papke R.T., Zhaxybayeva O., Feil E.J., Sommerfeld K., Muise D., Doolittle W.F.
    Proc. Natl. Acad. Sci. U.S.A. 104:14092-14097(2007)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MHHN-593833Imported.
    Tissue: Peripheral bloodImported.
  2. "A novel HLA-DRB1*0301 allele."
    Horn P.A., Mueller K., Blasczyk R.
    Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MHHN-593833Imported.
    Tissue: Peripheral bloodImported.

Entry informationi

Entry nameiA7E0V8_HUMAN
AccessioniPrimary (citable) accession number: A7E0V8
Entry historyi
Integrated into UniProtKB/TrEMBL: September 11, 2007
Last sequence update: September 11, 2007
Last modified: February 19, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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