A7DTG3 (SRTD4_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
SERTA domain-containing protein 4

Gene names

Name:

Sertad4

Organism

Mus musculus (Mouse) [Reference proteome]

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	377 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Tissue specificity	Highly expressed in adult epidermal tissues and in digits. Ref.3
Sequence similarities	Contains 1 SERTA domain.
Sequence caution	The sequence AAH60251.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 377	377	SERTA domain-containing protein 4		PRO_0000314140
Regions
	Domain	101 – 147	47	SERTA
	Compositional bias	205 – 264	60	Ser-rich
Experimental info
	Sequence conflict	1 – 2	2	MT → RP in AAH60251. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	A7DTG3 [UniParc]. Last modified September 11, 2007. Version 1. Checksum: 04AD821949D5996B	FASTA	377	41,096
	10 20 30 40 50 60 MTLVLSMNRF CEPIVSEGAA EIAGYQTLWE ADSYGGASPP GPAPVPSQGD RGASSHLAGS 70 80 90 100 110 120 HYRGIPNPIS TPKVTYFKRK YAEDEDLHPP LSSCSHKTIS IFEERAHILY MSLEKLRFID 130 140 150 160 170 180 DPEVYLRRSV LINNLMKRIH GEIVMQNSWC LPACSLGGTP AQEWFLAQDC PYRKRPRVAK 190 200 210 220 230 240 EEWEKIHTCC FYQECGGHCL NLPLSVNTSV GSTSAAAVAS AASSSSSPST SSSSSPSSSS 250 260 270 280 290 300 SPSPSPSSSS SSSSSSPLPL PSCSHHVDFD IGSAPIYKSQ IPASEIFVTN IRSLGVQEKV 310 320 330 340 350 360 KFNNDGKVSH ETSRDGDALG QEPVGNDLDF ECKGQFYDYF ETGYNERNRV SESWKKSLRK 370 KELSPSSKLC CNRGGKM

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J.
[2]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: C57BL/6. Tissue: Brain.
[3]	"Evolutionary conservation and murine embryonic expression of the gene encoding the SERTA domain-containing protein CDCA4 (HEPP)." Bennetts J.S., Fowles L.F., Berkman J.L., van Bueren K.L., Richman J.M., Simpson F., Wicking C. Gene 374:153-165(2006) [PubMed] [Europe PMC] [Abstract] Cited for: TISSUE SPECIFICITY.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL365326 Genomic DNA. Translation: CAO82111.1. BC060251 mRNA. Translation: AAH60251.1. Different initiation.
IPI	IPI00381056.
RefSeq	NP_001171265.1. NM_001177794.1. NP_937890.2. NM_198247.2.
UniGene	Mm.22806.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
IntAct	A7DTG3. 2 interactions.
STRING	10090.ENSMUSP00000116176.
Proteomic databases
PRIDE	A7DTG3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000016406; ENSMUSP00000016406; ENSMUSG00000016262. ENSMUST00000155579; ENSMUSP00000116176; ENSMUSG00000016262.
GeneID	214791.
KEGG	mmu:214791.
UCSC	uc007eds.2. mouse.
Organism-specific databases
CTD	56256.
MGI	MGI:2443496. Sertad4.
Phylogenomic databases
eggNOG	NOG25597.
GeneTree	ENSGT00530000063876.
HOGENOM	HOG000154425.
HOVERGEN	HBG108514.
InParanoid	A7DTG3.
OMA	IDDPEVY.
OrthoDB	EOG46T31X.
Gene expression databases
Bgee	A7DTG3.
CleanEx	MM_SERTAD4.
Genevestigator	A7DTG3.
Family and domain databases
InterPro	IPR009263. SERTA. [Graphical view]
Pfam	PF06031. SERTA. 1 hit. [Graphical view]
PROSITE	PS51053. SERTA. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	374472.
SOURCE	Search...

Entry information

Entry name

SRTD4_MOUSE

Accession

Primary (citable) accession number: A7DTG3
Secondary accession number(s): Q6PAK2

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	September 11, 2007
Last modified:	April 3, 2013
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program