A7BFV9 (A7BFV9_RAT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Epidermal growth factor receptor pathway substrate 15 EMBL BAF74783.1

Gene names

Name:

Eps15 RGD 1305550

Organism

Rattus norvegicus (Rat) EMBL BAF74783.1

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	897 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Molecular function	Receptor EMBL BAF74783.1
Gene Ontology (GO)
Molecular_function	calcium ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
Fcho2	Q3UQN2	2	EBI-6095043,EBI-6094986	From a different organism.
Sgip1	Q8VD37	2	EBI-6095043,EBI-776269	From a different organism.

Sequences

	Sequence		Length	Mass (Da)
	A7BFV9 [UniParc]. Last modified September 11, 2007. Version 1. Checksum: 8AC00E465C9DB8D7	FASTA	897	98,613
	10 20 30 40 50 60 MAAAAQLSLT QLSSGNPVYE KYYRQVEAGN TGRVLALDAA AFLKKSGLPD LILGKIWDLA 70 80 90 100 110 120 DTDGKGVLNK QEFFIALRLV ACAQNGLEVS LSSLNLAVPP PRFHDSSSPL LTSGTSVAEL 130 140 150 160 170 180 PWAVKSEDKA KYDAIFDSLS PVDGFLSGDK VKPVLLNSKL PVEILGRVWE LSDIDHDGKL 190 200 210 220 230 240 DRDEFAVAMF LVYCALEKEP VPMSLPPALV PPSKRKTWVV SPAEKAKYDE IFLKTDKDMD 250 260 270 280 290 300 GYVSGLEVRE TFLKTGLPST LLAHIWALCD TKNCGKLSKD QFALAFHLIN QKLIKGIDPP 310 320 330 340 350 360 HSLTPEMIPP SDRSSLQKNT IGSSPVADFS AIKELDTLNN EIIDLQREKN NVEQDLKEKE 370 380 390 400 410 420 DTVRQRTTEA QDLQDEVQRE SLNLQKLQAQ KQQVQELLDE LDEQKAQLEE QLKEVRKKCA 430 440 450 460 470 480 EEAQLISSLK AEITSQESQI STYEEELSKA REELSRLQQE TAQLEESVES GKAQLEPLQQ 490 500 510 520 530 540 HLQDSQQEIS SMQMRLAMKD LETDNNQSNW CSSPQSILVN GAADYCSLST SSSETANLNE 550 560 570 580 590 600 HAEGQNNLES EPIHPESSVR SSPEIAPSDV TDESEVVTAA DIEKVSPRFD DDKHSKEEDP 610 620 630 640 650 660 FNVESSSLTD AVADTNLDFF QSDPFVGSDP FKDDPFGKID PFGGDPFKGS DPFASDCFFK 670 680 690 700 710 720 QTSTDPFATS STDPFSASSN SSNTSVETWK HNDPFAPGGT VVAATDSATD PFASVFGNES 730 740 750 760 770 780 FGDGFADFST LSKVSNEDPF NPTISSSASS VVIPKPVLEE TPSKSEDVPP ALPPKTGTPT 790 800 810 820 830 840 RPCPPPPGKR PINKLDSSDP FKLNDPFQPF PGNDSPKEKD PDMFCDPFTS SSTTANKEAE 850 860 870 880 890 PSNFANFSAY PSEEDMIEWA KRESEREEEQ RLARLNQQEQ EDLELAIALS KSEISEA

References

[1]	"SGIP1alpha is an endocytic protein that directly interacts with phospholipids and Eps15." Uezu A., Horiuchi A., Kanda K., Kikuchi N., Umeda K., Tsujita K., Suetsugu S., Araki N., Yamamoto H., Takenawa T., Nakanishi H. J. Biol. Chem. 282:26481-26489(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB262963 mRNA. Translation: BAF74783.1.
IPI	IPI00358691.
UniGene	Rn.22316.
3D structure databases
ProteinModelPortal	A7BFV9.
SMR	A7BFV9. Positions 7-105, 121-215, 217-311.
ModBase	Search...
Protein-protein interaction databases
IntAct	A7BFV9. 2 interactions.
MINT	MINT-6168606.
STRING	10116.ENSRNOP00000014040. A7BFV9.
PTM databases
PhosphoSite	A7BFV9.
Proteomic databases
PaxDb	A7BFV9.
PRIDE	A7BFV9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
eggNOG	NOG301764.
HOGENOM	HOG000004804.
HOVERGEN	HBG005591.
InParanoid	A7BFV9.
Gene expression databases
Genevestigator	A7BFV9.
Family and domain databases
Gene3D	1.10.238.10. 3 hits.
InterPro	IPR011992. EF-hand-like_dom. IPR018247. EF_Hand_1_Ca_BS. IPR002048. EF_hand_dom. IPR000261. EPS15_homology. IPR003903. Ubiquitin-int_motif. [Graphical view]
SMART	SM00054. EFh. 4 hits. SM00027. EH. 3 hits. SM00726. UIM. 2 hits. [Graphical view]
PROSITE	PS00018. EF_HAND_1. 2 hits. PS50222. EF_HAND_2. 4 hits. PS50031. EH. 3 hits. PS50330. UIM. 2 hits. [Graphical view]
ProtoNet	Search...
Other
NextBio	35564626.

Entry information

Entry name

A7BFV9_RAT

Accession

Primary (citable) accession number: A7BFV9

Entry history

Integrated into UniProtKB/TrEMBL:	September 11, 2007
Last sequence update:	September 11, 2007
Last modified:	May 1, 2013
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)