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A7BFV9

- A7BFV9_RAT

UniProt

A7BFV9 - A7BFV9_RAT

Protein
Submitted name:

Epidermal growth factor receptor pathway substrate 15

Gene
N/A
Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 45 (01 Oct 2014)
      Sequence version 1 (11 Sep 2007)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. calcium ion binding Source: InterPro
    2. protein binding Source: UniProtKB

    Keywords - Molecular functioni

    ReceptorImported

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Epidermal growth factor receptor pathway substrate 15Imported
    OrganismiRattus norvegicus (Rat)Imported
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

    PTM / Processingi

    Proteomic databases

    PaxDbiA7BFV9.
    PRIDEiA7BFV9.

    PTM databases

    PhosphoSiteiA7BFV9.

    Expressioni

    Gene expression databases

    GenevestigatoriA7BFV9.

    Interactioni

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    FCHO1O145262EBI-6095043,EBI-719823From a different organism.
    Fcho2Q3UQN22EBI-6095043,EBI-6094986From a different organism.
    Sgip1Q8VD374EBI-6095043,EBI-776269From a different organism.

    Protein-protein interaction databases

    IntActiA7BFV9. 8 interactions.
    MINTiMINT-6168606.
    STRINGi10116.ENSRNOP00000014040.

    Structurei

    3D structure databases

    ProteinModelPortaliA7BFV9.
    SMRiA7BFV9. Positions 7-105, 121-215, 217-311.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    eggNOGiNOG301764.
    HOGENOMiHOG000004804.
    HOVERGENiHBG005591.
    InParanoidiA7BFV9.

    Family and domain databases

    Gene3Di1.10.238.10. 3 hits.
    InterProiIPR011992. EF-hand-dom_pair.
    IPR018247. EF_Hand_1_Ca_BS.
    IPR002048. EF_hand_dom.
    IPR000261. EPS15_homology.
    IPR003903. Ubiquitin-int_motif.
    [Graphical view]
    SMARTiSM00054. EFh. 4 hits.
    SM00027. EH. 3 hits.
    SM00726. UIM. 2 hits.
    [Graphical view]
    PROSITEiPS00018. EF_HAND_1. 2 hits.
    PS50222. EF_HAND_2. 4 hits.
    PS50031. EH. 3 hits.
    PS50330. UIM. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A7BFV9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAAAAQLSLT QLSSGNPVYE KYYRQVEAGN TGRVLALDAA AFLKKSGLPD    50
    LILGKIWDLA DTDGKGVLNK QEFFIALRLV ACAQNGLEVS LSSLNLAVPP 100
    PRFHDSSSPL LTSGTSVAEL PWAVKSEDKA KYDAIFDSLS PVDGFLSGDK 150
    VKPVLLNSKL PVEILGRVWE LSDIDHDGKL DRDEFAVAMF LVYCALEKEP 200
    VPMSLPPALV PPSKRKTWVV SPAEKAKYDE IFLKTDKDMD GYVSGLEVRE 250
    TFLKTGLPST LLAHIWALCD TKNCGKLSKD QFALAFHLIN QKLIKGIDPP 300
    HSLTPEMIPP SDRSSLQKNT IGSSPVADFS AIKELDTLNN EIIDLQREKN 350
    NVEQDLKEKE DTVRQRTTEA QDLQDEVQRE SLNLQKLQAQ KQQVQELLDE 400
    LDEQKAQLEE QLKEVRKKCA EEAQLISSLK AEITSQESQI STYEEELSKA 450
    REELSRLQQE TAQLEESVES GKAQLEPLQQ HLQDSQQEIS SMQMRLAMKD 500
    LETDNNQSNW CSSPQSILVN GAADYCSLST SSSETANLNE HAEGQNNLES 550
    EPIHPESSVR SSPEIAPSDV TDESEVVTAA DIEKVSPRFD DDKHSKEEDP 600
    FNVESSSLTD AVADTNLDFF QSDPFVGSDP FKDDPFGKID PFGGDPFKGS 650
    DPFASDCFFK QTSTDPFATS STDPFSASSN SSNTSVETWK HNDPFAPGGT 700
    VVAATDSATD PFASVFGNES FGDGFADFST LSKVSNEDPF NPTISSSASS 750
    VVIPKPVLEE TPSKSEDVPP ALPPKTGTPT RPCPPPPGKR PINKLDSSDP 800
    FKLNDPFQPF PGNDSPKEKD PDMFCDPFTS SSTTANKEAE PSNFANFSAY 850
    PSEEDMIEWA KRESEREEEQ RLARLNQQEQ EDLELAIALS KSEISEA 897
    Length:897
    Mass (Da):98,613
    Last modified:September 11, 2007 - v1
    Checksum:i8AC00E465C9DB8D7
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB262963 mRNA. Translation: BAF74783.1.
    UniGeneiRn.22316.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB262963 mRNA. Translation: BAF74783.1 .
    UniGenei Rn.22316.

    3D structure databases

    ProteinModelPortali A7BFV9.
    SMRi A7BFV9. Positions 7-105, 121-215, 217-311.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi A7BFV9. 8 interactions.
    MINTi MINT-6168606.
    STRINGi 10116.ENSRNOP00000014040.

    PTM databases

    PhosphoSitei A7BFV9.

    Proteomic databases

    PaxDbi A7BFV9.
    PRIDEi A7BFV9.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    eggNOGi NOG301764.
    HOGENOMi HOG000004804.
    HOVERGENi HBG005591.
    InParanoidi A7BFV9.

    Miscellaneous databases

    NextBioi 35564626.

    Gene expression databases

    Genevestigatori A7BFV9.

    Family and domain databases

    Gene3Di 1.10.238.10. 3 hits.
    InterProi IPR011992. EF-hand-dom_pair.
    IPR018247. EF_Hand_1_Ca_BS.
    IPR002048. EF_hand_dom.
    IPR000261. EPS15_homology.
    IPR003903. Ubiquitin-int_motif.
    [Graphical view ]
    SMARTi SM00054. EFh. 4 hits.
    SM00027. EH. 3 hits.
    SM00726. UIM. 2 hits.
    [Graphical view ]
    PROSITEi PS00018. EF_HAND_1. 2 hits.
    PS50222. EF_HAND_2. 4 hits.
    PS50031. EH. 3 hits.
    PS50330. UIM. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "SGIP1alpha is an endocytic protein that directly interacts with phospholipids and Eps15."
      Uezu A., Horiuchi A., Kanda K., Kikuchi N., Umeda K., Tsujita K., Suetsugu S., Araki N., Yamamoto H., Takenawa T., Nakanishi H.
      J. Biol. Chem. 282:26481-26489(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiA7BFV9_RAT
    AccessioniPrimary (citable) accession number: A7BFV9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 11, 2007
    Last sequence update: September 11, 2007
    Last modified: October 1, 2014
    This is version 45 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)