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Protein
Submitted name:

Epidermal growth factor receptor pathway substrate 15

Gene
N/A
Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Calcium bindingi173 – 184PROSITE-ProRule annotationAdd BLAST12
Calcium bindingi236 – 247PROSITE-ProRule annotationAdd BLAST12

GO - Molecular functioni

Keywordsi

Molecular functionReceptorImported
LigandCalciumPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Epidermal growth factor receptor pathway substrate 15Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus

PTM / Processingi

Proteomic databases

PRIDEiA7BFV9

PTM databases

iPTMnetiA7BFV9
PhosphoSitePlusiA7BFV9

Interactioni

Binary interactionsi

Show more details

Protein-protein interaction databases

IntActiA7BFV9, 8 interactors
MINTiA7BFV9

Structurei

3D structure databases

ProteinModelPortaliA7BFV9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini15 – 104EHInterPro annotationAdd BLAST90
Domaini48 – 83EF-handInterPro annotationAdd BLAST36
Domaini128 – 216EHInterPro annotationAdd BLAST89
Domaini160 – 195EF-handInterPro annotationAdd BLAST36
Domaini223 – 258EF-handInterPro annotationAdd BLAST36
Domaini224 – 314EHInterPro annotationAdd BLAST91
Domaini262 – 292EF-handInterPro annotationAdd BLAST31

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili335 – 474Sequence analysisAdd BLAST140
Coiled coili861 – 882Sequence analysisAdd BLAST22

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0998 Eukaryota
ENOG410XTDR LUCA
HOGENOMiHOG000004804
HOVERGENiHBG005591

Family and domain databases

InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
IPR000261 EH_dom
IPR003903 UIM_dom
PfamiView protein in Pfam
PF12763 EF-hand_4, 3 hits
SMARTiView protein in SMART
SM00054 EFh, 4 hits
SM00027 EH, 3 hits
SM00726 UIM, 2 hits
SUPFAMiSSF47473 SSF47473, 3 hits
PROSITEiView protein in PROSITE
PS00018 EF_HAND_1, 2 hits
PS50222 EF_HAND_2, 4 hits
PS50031 EH, 3 hits
PS50330 UIM, 2 hits

Sequencei

Sequence statusi: Complete.

A7BFV9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAAAQLSLT QLSSGNPVYE KYYRQVEAGN TGRVLALDAA AFLKKSGLPD
60 70 80 90 100
LILGKIWDLA DTDGKGVLNK QEFFIALRLV ACAQNGLEVS LSSLNLAVPP
110 120 130 140 150
PRFHDSSSPL LTSGTSVAEL PWAVKSEDKA KYDAIFDSLS PVDGFLSGDK
160 170 180 190 200
VKPVLLNSKL PVEILGRVWE LSDIDHDGKL DRDEFAVAMF LVYCALEKEP
210 220 230 240 250
VPMSLPPALV PPSKRKTWVV SPAEKAKYDE IFLKTDKDMD GYVSGLEVRE
260 270 280 290 300
TFLKTGLPST LLAHIWALCD TKNCGKLSKD QFALAFHLIN QKLIKGIDPP
310 320 330 340 350
HSLTPEMIPP SDRSSLQKNT IGSSPVADFS AIKELDTLNN EIIDLQREKN
360 370 380 390 400
NVEQDLKEKE DTVRQRTTEA QDLQDEVQRE SLNLQKLQAQ KQQVQELLDE
410 420 430 440 450
LDEQKAQLEE QLKEVRKKCA EEAQLISSLK AEITSQESQI STYEEELSKA
460 470 480 490 500
REELSRLQQE TAQLEESVES GKAQLEPLQQ HLQDSQQEIS SMQMRLAMKD
510 520 530 540 550
LETDNNQSNW CSSPQSILVN GAADYCSLST SSSETANLNE HAEGQNNLES
560 570 580 590 600
EPIHPESSVR SSPEIAPSDV TDESEVVTAA DIEKVSPRFD DDKHSKEEDP
610 620 630 640 650
FNVESSSLTD AVADTNLDFF QSDPFVGSDP FKDDPFGKID PFGGDPFKGS
660 670 680 690 700
DPFASDCFFK QTSTDPFATS STDPFSASSN SSNTSVETWK HNDPFAPGGT
710 720 730 740 750
VVAATDSATD PFASVFGNES FGDGFADFST LSKVSNEDPF NPTISSSASS
760 770 780 790 800
VVIPKPVLEE TPSKSEDVPP ALPPKTGTPT RPCPPPPGKR PINKLDSSDP
810 820 830 840 850
FKLNDPFQPF PGNDSPKEKD PDMFCDPFTS SSTTANKEAE PSNFANFSAY
860 870 880 890
PSEEDMIEWA KRESEREEEQ RLARLNQQEQ EDLELAIALS KSEISEA
Length:897
Mass (Da):98,613
Last modified:September 11, 2007 - v1
Checksum:i8AC00E465C9DB8D7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB262963 mRNA Translation: BAF74783.1
UniGeneiRn.22316

Similar proteinsi

Entry informationi

Entry nameiA7BFV9_RAT
AccessioniPrimary (citable) accession number: A7BFV9
Entry historyiIntegrated into UniProtKB/TrEMBL: September 11, 2007
Last sequence update: September 11, 2007
Last modified: May 23, 2018
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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