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Protein

Glycerol-3-phosphate dehydrogenase [NAD(+)]

Gene

BBOV_IV004480

Organism
Babesia bovis
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei123 – 1231SubstrateUniRule annotation
Active sitei207 – 2071Proton acceptorUniRule annotation

GO - Molecular functioni

  1. glycerol-3-phosphate dehydrogenase [NAD+] activity Source: UniProtKB-EC
  2. NAD binding Source: InterPro

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
  2. glycerol-3-phosphate catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationImported

Keywords - Ligandi

NADUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenase [NAD(+)]UniRule annotation (EC:1.1.1.8UniRule annotation)
Gene namesi
Name:BBOV_IV004480Imported
ORF Names:BBOV_IV004480Imported
OrganismiBabesia bovisImported
Taxonomic identifieri5865 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaPiroplasmidaBabesiidaeBabesia
ProteomesiUP000002173: Partially assembled WGS sequence

Organism-specific databases

EuPathDBiPiroplasmaDB:BBOV_IV004480.

Subcellular locationi

GO - Cellular componenti

  1. glycerol-3-phosphate dehydrogenase complex Source: InterPro
Complete GO annotation...

Structurei

3D structure databases

ProteinModelPortaliA7AQJ0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni271 – 2722Substrate bindingUniRule annotation

Sequence similaritiesi

Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.UniRule annotation

Phylogenomic databases

KOiK00006.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
InterProiIPR008927. 6-PGluconate_DH_C-like.
IPR013328. DH_multihelical.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR017751. G3P_DH_NAD-dep_euk.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR11728. PTHR11728. 1 hit.
PfamiPF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000114. Glycerol-3-P_dh. 1 hit.
PRINTSiPR00077. GPDHDRGNASE.
SUPFAMiSSF48179. SSF48179. 1 hit.
TIGRFAMsiTIGR03376. glycerol3P_DH. 1 hit.
PROSITEiPS00957. NAD_G3PDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A7AQJ0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MATGKKVCVV GCGNWGSAVA KLVAENTPRY PEFDDTVIIY VLEEVFEGRN
60 70 80 90 100
LSEIINTDHE NKKYLPGIKL PHNILAVPDL KQCIQDSDIF IIVIPHQFVN
110 120 130 140 150
STVAKIKSFN VMKPGSLAIN LVKGIELTEK VVNCFTDTIE KELGIPCLAL
160 170 180 190 200
SGANVAKNVA MEEFSEATIG YKNKEHAVLF QRLFDRPYFK INCVPGVSAV
210 220 230 240 250
QVFGAIKNAV AIAAGFCDGL GLGSNTKAAI MRIGLNEIYR FACKFFKDIN
260 270 280 290 300
TDVVFESAGV ADLITTCIGG RNVRCAAEFA KHGGKKSWHD IENEMLGGQK
310 320 330 340 350
LQGTSTCEEV YKVLVAHNME NDFPLFVVTY NIAFQGAEPA ELIRKFSNET

LNPF
Length:354
Mass (Da):38,854
Last modified:September 11, 2007 - v1
Checksum:iA61041E1CF19F8A8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK441831 mRNA. Translation: BAN65625.1.
AAXT01000002 Genomic DNA. Translation: EDO06809.1.
RefSeqiXP_001610377.1. XM_001610327.1.

Genome annotation databases

GeneIDi5478611.
KEGGibbo:BBOV_IV004480.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK441831 mRNA. Translation: BAN65625.1.
AAXT01000002 Genomic DNA. Translation: EDO06809.1.
RefSeqiXP_001610377.1. XM_001610327.1.

3D structure databases

ProteinModelPortaliA7AQJ0.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi5478611.
KEGGibbo:BBOV_IV004480.

Organism-specific databases

EuPathDBiPiroplasmaDB:BBOV_IV004480.

Phylogenomic databases

KOiK00006.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
InterProiIPR008927. 6-PGluconate_DH_C-like.
IPR013328. DH_multihelical.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR017751. G3P_DH_NAD-dep_euk.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR11728. PTHR11728. 1 hit.
PfamiPF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000114. Glycerol-3-P_dh. 1 hit.
PRINTSiPR00077. GPDHDRGNASE.
SUPFAMiSSF48179. SSF48179. 1 hit.
TIGRFAMsiTIGR03376. glycerol3P_DH. 1 hit.
PROSITEiPS00957. NAD_G3PDH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: T2BoImported.
  2. Nene V.
    Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: T2BoImported.
  3. "The Babesia bovis gene and promoter model: an update from full-length EST analysis."
    Yamagishi J., Wakaguri H., Yokoyama N., Yamashita R., Suzuki Y., Xuan X., Igarashi I.
    BMC Genomics 15:678-678(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: TexasImported.

Entry informationi

Entry nameiA7AQJ0_BABBO
AccessioniPrimary (citable) accession number: A7AQJ0
Entry historyi
Integrated into UniProtKB/TrEMBL: September 11, 2007
Last sequence update: September 11, 2007
Last modified: February 4, 2015
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.