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A7A261 (LSB3_YEAS7) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
LAS seventeen-binding protein 3

Short name=LAS17-binding protein 3
Gene names
Name:LSB3
ORF Names:SCY_1771
OrganismSaccharomyces cerevisiae (strain YJM789) (Baker's yeast) [Complete proteome]
Taxonomic identifier307796 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length459 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Subunit structure

Interacts with LAS17 By similarity.

Subcellular location

Cytoplasm By similarity.

Post-translational modification

Phosphorylation of Ser-397 is induced 2-fold in response to mating pheromone By similarity.

Sequence similarities

Belongs to the SH3YL1 family.

Contains 1 SH3 domain.

Sequence caution

The sequence EDN59172.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
   Cellular componentCytoplasm
   DomainSH3 domain
   PTMPhosphoprotein
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 459459LAS seventeen-binding protein 3
PRO_0000345086

Regions

Domain400 – 45960SH3
Compositional bias229 – 28456Asp-rich

Amino acid modifications

Modified residue2271Phosphoserine By similarity
Modified residue2981Phosphothreonine By similarity
Modified residue3001Phosphoserine By similarity
Modified residue3031Phosphoserine By similarity
Modified residue3931Phosphothreonine By similarity
Modified residue3971Phosphoserine By similarity
Modified residue4021Phosphoserine By similarity
Modified residue4161Phosphoserine By similarity

Sequences

Sequence LengthMass (Da)Tools
A7A261 [UniParc].

Last modified July 22, 2008. Version 2.
Checksum: F486C787B5771AAC

FASTA45949,344
        10         20         30         40         50         60 
MGINNPIPRS LKSETKKAAK ILASFVKPNQ VFGADQVIPP DVLKRAKGLA IITILKAGFL 

        70         80         90        100        110        120 
FSGRAGSGVI VARLKDGTWS APSAIAMAGA GAGGMVGIEL TDFVFILNTQ DAVKSFSEFG 

       130        140        150        160        170        180 
TITLGGNVSV SAGPLGRSAE AAASASAGGV AAVFAYSKSK GLFAGVSVEG SAIIERREAN 

       190        200        210        220        230        240 
RKFYGDNCTA KMILSGRIRP PPAVDPLFRV LESRAFNYRP SNGGRGSFDD DEDDYYDDDD 

       250        260        270        280        290        300 
YYNDIPSSFS STDASSTRPN TRSTRRRAQS GSRYTFDDDD DDDDYGTGYS RNSRLAPTNS 

       310        320        330        340        350        360 
GGSGGKLDDP SGASSYYASH RRSGTAQSRA RSSRNRWADD EYDDYDDDYE SGYRRGNGRD 

       370        380        390        400        410        420 
RTKDREVDDL SNRFSKSRIS SASTPQTSQG RFTAPTSPST SSPKAVALYS FAGEESGDLP 

       430        440        450 
FRKGDVITIL KKSDSQNDWW TGRVNGREGI FPANYVELV 

« Hide

References

[1]"Genome sequencing and comparative analysis of Saccharomyces cerevisiae strain YJM789."
Wei W., McCusker J.H., Hyman R.W., Jones T., Ning Y., Cao Z., Gu Z., Bruno D., Miranda M., Nguyen M., Wilhelmy J., Komp C., Tamse R., Wang X., Jia P., Luedi P., Oefner P.J., David L. expand/collapse author list , Dietrich F.S., Li Y., Davis R.W., Steinmetz L.M.
Proc. Natl. Acad. Sci. U.S.A. 104:12825-12830(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: YJM789.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AAFW02000176 Genomic DNA. Translation: EDN59172.1. Sequence problems.

3D structure databases

ProteinModelPortalA7A261.
SMRA7A261. Positions 368-459.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

OrthoDBEOG7X9GH6.

Family and domain databases

InterProIPR001452. SH3_domain.
IPR007461. Ysc84_actin-binding.
[Graphical view]
PfamPF04366. DUF500. 1 hit.
PF00018. SH3_1. 1 hit.
[Graphical view]
PRINTSPR00452. SH3DOMAIN.
SMARTSM00326. SH3. 1 hit.
[Graphical view]
SUPFAMSSF50044. SSF50044. 1 hit.
PROSITEPS50002. SH3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameLSB3_YEAS7
AccessionPrimary (citable) accession number: A7A261
Entry history
Integrated into UniProtKB/Swiss-Prot: July 22, 2008
Last sequence update: July 22, 2008
Last modified: November 13, 2013
This is version 26 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families