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Protein

Pre-rRNA-processing protein RIX1

Gene

RIX1

Organism
Saccharomyces cerevisiae (strain YJM789) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA and the nucleoplasmic transit of the pre-60S ribosomal subunits. Regulates pre-60S association of the critical remodeling factor MDN1.By similarity

GO - Biological processi

Keywordsi

Biological processRibosome biogenesis, rRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Pre-rRNA-processing protein RIX1
Alternative name(s):
Ribosomal export protein 1
Gene namesi
Name:RIX1
ORF Names:SCY_2587
OrganismiSaccharomyces cerevisiae (strain YJM789) (Baker's yeast)
Taxonomic identifieri307796 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000007060 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00003089222 – 763Pre-rRNA-processing protein RIX1Add BLAST762

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylserineBy similarity1

Keywords - PTMi

Acetylation

Proteomic databases

PRIDEiA6ZTA3.

Interactioni

Subunit structurei

Component of the RIX1 complex, composed of IPI1, RIX1/IPI2 and IPI3 in a 1:2:2 stoichiometry. The complex interacts (via RIX1) with MDN1 (via its hexameric AAA ATPase ring) and the pre-60S ribosome particles. Interacts with NUG1.By similarity

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi690 – 763Glu-richAdd BLAST74

Sequence similaritiesi

Belongs to the RIX1/PELP1 family.Curated

Phylogenomic databases

OrthoDBiEOG092C0SY4.

Family and domain databases

InterProiView protein in InterPro
IPR012583. RIX1_N.
PfamiView protein in Pfam
PF08167. RIX1. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

A6ZTA3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEEFIAVST LARNLEIAKG NEFHTILATL RSPVYINEQL LKSELSFLVT
60 70 80 90 100
KILKLIRSGN DFDLWKGCHT SVVTCAYNPL VLSTHGGQLL AAIYSRLEQK
110 120 130 140 150
TGFYSSVISS SHGKQLFNIL ISSVAIIIDL MKNKPTLSRE ALVPKLKAII
160 170 180 190 200
PTLITLSQYE PELVLPVLQR ILKRNTTTFK PFTNKFRTVL INLIISDYAS
210 220 230 240 250
LGTKTQRLVC ENFAYLHLLK IQVSDTSDDE TQAHHKIYAD SNWRTGLMSI
260 270 280 290 300
LSQFKPIIQL CGEILDFEQD NELYKLIKSL PVIDESNNKE EFLPSLKLDF
310 320 330 340 350
NAPLTLWEIP QRLSLLADML VAFISLPTPF PIRVPLGGIN SLCEVLLGVS
360 370 380 390 400
NKYLPLKKEL RRDNELNGVI NTILPQIQFQ GIRLWEIMVS KYGKCGLSFF
410 420 430 440 450
EGILSSIELF IPLKKKSNNE IDFNVVGSLK FEFATVFRLV NMILSHLGHQ
460 470 480 490 500
LNIISVISQL IEVALFLSHD KTLIDSLFKN RKSIMKQQTK TKQSKRSKSA
510 520 530 540 550
EGAFSDIYTH PELFVCKNSM NWFNEINDFF ITALNNWILP STPHIQILKY
560 570 580 590 600
SITQSLRLKE RFGYIPESFV NLLRCEVLHP GSERVSILPI AISLLKNIND
610 620 630 640 650
DMFELLCHPK VPVGMVYQLH KPLDLGEDGE VRDDINKKEV ETNESSSNAN
660 670 680 690 700
TGLETLKALE NLENVTIPEP KHEVPKVVDD TAIFKKRSVE EVIERESTSS
710 720 730 740 750
HKKVKFVEET TVDNGEELIV KKAVNQTKEE EKPMEDSEDE EQEEFEIPAI
760
ELSDDEEEEE EEE
Length:763
Mass (Da):86,797
Last modified:September 11, 2007 - v1
Checksum:i3BEA00647D17B084
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFW02000082 Genomic DNA. Translation: EDN62434.1.

Genome annotation databases

EnsemblFungiiEDN62434; EDN62434; SCY_2587.

Similar proteinsi

Entry informationi

Entry nameiRIX1_YEAS7
AccessioniPrimary (citable) accession number: A6ZTA3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: September 11, 2007
Last modified: October 25, 2017
This is version 28 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families