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A6ZMK5 (EIF3I_YEAS7) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Eukaryotic translation initiation factor 3 subunit I

Short name=eIF3i
Alternative name(s):
Eukaryotic translation initiation factor 3 39 kDa subunit homolog
Short name=eIF-3 39 kDa subunit homolog
Gene names
Name:TIF34
ORF Names:SCY_4321
OrganismSaccharomyces cerevisiae (strain YJM789) (Baker's yeast) [Complete proteome]
Taxonomic identifier307796 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length347 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome By similarity. HAMAP-Rule MF_03008

Subunit structure

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex By similarity.

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_03008.

Sequence similarities

Belongs to the eIF-3 subunit I family.

Contains 5 WD repeats.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 347347Eukaryotic translation initiation factor 3 subunit I HAMAP-Rule MF_03008
PRO_0000366904

Regions

Repeat8 – 4740WD 1 HAMAP-Rule MF_03008
Repeat50 – 8940WD 2 HAMAP-Rule MF_03008
Repeat149 – 19042WD 3 HAMAP-Rule MF_03008
Repeat194 – 23340WD 4 HAMAP-Rule MF_03008
Repeat291 – 33040WD 5 HAMAP-Rule MF_03008

Amino acid modifications

Modified residue3021Phosphoserine By similarity

Sequences

Sequence LengthMass (Da)Tools
A6ZMK5 [UniParc].

Last modified September 11, 2007. Version 1.
Checksum: E6C0D0B275E87622

FASTA34738,755
        10         20         30         40         50         60 
MKAIKLTGHE RPLTQVKYNK EGDLLFSCSK DSSASVWYSL NGERLGTLDG HTGTIWSIDV 

        70         80         90        100        110        120 
DCFTKYCVTG SADYSIKLWD VSNGQCVATW KSPVPVKRVE FSPCGNYFLA ILDNVMKNPG 

       130        140        150        160        170        180 
SINIYEIERD SATHELTKVS EEPIHKIITH EGLDAATVAG WSTKGKYIIA GHKDGKISKY 

       190        200        210        220        230        240 
DVSNNYEYVD SIDLHEKSIS DMQFSPDLTY FITSSRDTNS FLVDVSTLQV LKKYETDCPL 

       250        260        270        280        290        300 
NTAVITPLKE FIILGGGQEA KDVTTTSANE GKFEARFYHK IFEEEIGRVQ GHFGPLNTVA 

       310        320        330        340 
ISPQGTSYAS GGEDGFIRLH HFEKSYFDFK YDVEKAAEAK EHMQEAN 

« Hide

References

[1]"Genome sequencing and comparative analysis of Saccharomyces cerevisiae strain YJM789."
Wei W., McCusker J.H., Hyman R.W., Jones T., Ning Y., Cao Z., Gu Z., Bruno D., Miranda M., Nguyen M., Wilhelmy J., Komp C., Tamse R., Wang X., Jia P., Luedi P., Oefner P.J., David L. expand/collapse author list , Dietrich F.S., Li Y., Davis R.W., Steinmetz L.M.
Proc. Natl. Acad. Sci. U.S.A. 104:12825-12830(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: YJM789.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AAFW02000021 Genomic DNA. Translation: EDN64079.1.

3D structure databases

ProteinModelPortalA6ZMK5.
SMRA6ZMK5. Positions 1-342.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActA6ZMK5. 2 interactions.
MINTMINT-7980995.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

OrthoDBEOG7Z95X9.

Family and domain databases

Gene3D2.130.10.10. 1 hit.
HAMAPMF_03008. eIF3i.
InterProIPR027525. eIF3i.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamPF00400. WD40. 4 hits.
[Graphical view]
SMARTSM00320. WD40. 6 hits.
[Graphical view]
SUPFAMSSF50978. SSF50978. 1 hit.
PROSITEPS00678. WD_REPEATS_1. 1 hit.
PS50082. WD_REPEATS_2. 3 hits.
PS50294. WD_REPEATS_REGION. 2 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameEIF3I_YEAS7
AccessionPrimary (citable) accession number: A6ZMK5
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: September 11, 2007
Last modified: February 19, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Translation initiation factors

List of translation initiation factor entries