Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

A6ZMK5

- EIF3I_YEAS7

UniProt

A6ZMK5 - EIF3I_YEAS7

Protein

Eukaryotic translation initiation factor 3 subunit I

Gene

TIF34

Organism
Saccharomyces cerevisiae (strain YJM789) (Baker's yeast)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 38 (01 Oct 2014)
      Sequence version 1 (11 Sep 2007)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.UniRule annotation

    GO - Molecular functioni

    1. translation initiation factor activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. formation of translation preinitiation complex Source: UniProtKB-HAMAP
    2. regulation of translational initiation Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Initiation factor

    Keywords - Biological processi

    Protein biosynthesis

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Eukaryotic translation initiation factor 3 subunit IUniRule annotation
    Short name:
    eIF3iUniRule annotation
    Alternative name(s):
    Eukaryotic translation initiation factor 3 39 kDa subunit homologUniRule annotation
    Short name:
    eIF-3 39 kDa subunit homologUniRule annotation
    Gene namesi
    Name:TIF34UniRule annotation
    ORF Names:SCY_4321
    OrganismiSaccharomyces cerevisiae (strain YJM789) (Baker's yeast)
    Taxonomic identifieri307796 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000007060: Unassembled WGS sequence

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. eukaryotic 43S preinitiation complex Source: UniProtKB-HAMAP
    2. eukaryotic 48S preinitiation complex Source: UniProtKB-HAMAP
    3. eukaryotic translation initiation factor 3 complex Source: UniProtKB-HAMAP

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 347347Eukaryotic translation initiation factor 3 subunit IPRO_0000366904Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei302 – 3021PhosphoserineBy similarity

    Keywords - PTMi

    Phosphoprotein

    Interactioni

    Subunit structurei

    Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.UniRule annotation

    Protein-protein interaction databases

    IntActiA6ZMK5. 2 interactions.
    MINTiMINT-7980995.

    Structurei

    3D structure databases

    ProteinModelPortaliA6ZMK5.
    SMRiA6ZMK5. Positions 1-342.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Repeati8 – 4740WD 1Add
    BLAST
    Repeati50 – 8940WD 2Add
    BLAST
    Repeati149 – 19042WD 3Add
    BLAST
    Repeati194 – 23340WD 4Add
    BLAST
    Repeati291 – 33040WD 5Add
    BLAST

    Sequence similaritiesi

    Belongs to the eIF-3 subunit I family.UniRule annotation
    Contains 5 WD repeats.UniRule annotation

    Keywords - Domaini

    Repeat, WD repeat

    Phylogenomic databases

    OrthoDBiEOG7Z95X9.

    Family and domain databases

    Gene3Di2.130.10.10. 1 hit.
    HAMAPiMF_03008. eIF3i.
    InterProiIPR027525. eIF3i.
    IPR015943. WD40/YVTN_repeat-like_dom.
    IPR001680. WD40_repeat.
    IPR019775. WD40_repeat_CS.
    IPR017986. WD40_repeat_dom.
    [Graphical view]
    PfamiPF00400. WD40. 4 hits.
    [Graphical view]
    SMARTiSM00320. WD40. 6 hits.
    [Graphical view]
    SUPFAMiSSF50978. SSF50978. 1 hit.
    PROSITEiPS00678. WD_REPEATS_1. 1 hit.
    PS50082. WD_REPEATS_2. 3 hits.
    PS50294. WD_REPEATS_REGION. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A6ZMK5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKAIKLTGHE RPLTQVKYNK EGDLLFSCSK DSSASVWYSL NGERLGTLDG    50
    HTGTIWSIDV DCFTKYCVTG SADYSIKLWD VSNGQCVATW KSPVPVKRVE 100
    FSPCGNYFLA ILDNVMKNPG SINIYEIERD SATHELTKVS EEPIHKIITH 150
    EGLDAATVAG WSTKGKYIIA GHKDGKISKY DVSNNYEYVD SIDLHEKSIS 200
    DMQFSPDLTY FITSSRDTNS FLVDVSTLQV LKKYETDCPL NTAVITPLKE 250
    FIILGGGQEA KDVTTTSANE GKFEARFYHK IFEEEIGRVQ GHFGPLNTVA 300
    ISPQGTSYAS GGEDGFIRLH HFEKSYFDFK YDVEKAAEAK EHMQEAN 347
    Length:347
    Mass (Da):38,755
    Last modified:September 11, 2007 - v1
    Checksum:iE6C0D0B275E87622
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAFW02000021 Genomic DNA. Translation: EDN64079.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAFW02000021 Genomic DNA. Translation: EDN64079.1 .

    3D structure databases

    ProteinModelPortali A6ZMK5.
    SMRi A6ZMK5. Positions 1-342.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi A6ZMK5. 2 interactions.
    MINTi MINT-7980995.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    OrthoDBi EOG7Z95X9.

    Family and domain databases

    Gene3Di 2.130.10.10. 1 hit.
    HAMAPi MF_03008. eIF3i.
    InterProi IPR027525. eIF3i.
    IPR015943. WD40/YVTN_repeat-like_dom.
    IPR001680. WD40_repeat.
    IPR019775. WD40_repeat_CS.
    IPR017986. WD40_repeat_dom.
    [Graphical view ]
    Pfami PF00400. WD40. 4 hits.
    [Graphical view ]
    SMARTi SM00320. WD40. 6 hits.
    [Graphical view ]
    SUPFAMi SSF50978. SSF50978. 1 hit.
    PROSITEi PS00678. WD_REPEATS_1. 1 hit.
    PS50082. WD_REPEATS_2. 3 hits.
    PS50294. WD_REPEATS_REGION. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: YJM789.

    Entry informationi

    Entry nameiEIF3I_YEAS7
    AccessioniPrimary (citable) accession number: A6ZMK5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 24, 2009
    Last sequence update: September 11, 2007
    Last modified: October 1, 2014
    This is version 38 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Translation initiation factors
      List of translation initiation factor entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3