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A6ZLH8

- ERT1_YEAS7

UniProt

A6ZLH8 - ERT1_YEAS7

Protein

Transcription activator of gluconeogenesis

Gene

ERT1

Organism
Saccharomyces cerevisiae (strain YJM789) (Baker's yeast)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 38 (01 Oct 2014)
      Sequence version 1 (11 Sep 2007)
      Previous versions | rss
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    Functioni

    Transcription factor which regulates nonfermentable carbon utilization. Activator of gluconeogenetic genes By similarity.By similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    DNA bindingi40 – 6829Zn(2)-C6 fungal-typePROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-KW
    2. sequence-specific DNA binding RNA polymerase II transcription factor activity Source: InterPro
    3. signal transducer activity Source: InterPro
    4. zinc ion binding Source: InterPro

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-KW

    Keywords - Molecular functioni

    Activator

    Keywords - Biological processi

    Gluconeogenesis, Transcription, Transcription regulation

    Keywords - Ligandi

    DNA-binding, Metal-binding, Zinc

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Transcription activator of gluconeogenesis
    Alternative name(s):
    Ethanol regulator of translation 1
    Gene namesi
    Name:ERT1
    ORF Names:SCY_0448
    OrganismiSaccharomyces cerevisiae (strain YJM789) (Baker's yeast)
    Taxonomic identifieri307796 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000007060: Unassembled WGS sequence

    Subcellular locationi

    Nucleus PROSITE-ProRule annotation

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 529529Transcription activator of gluconeogenesisPRO_0000406475Add
    BLAST

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini408 – 48073PASPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the ERT1/acuK family.Curated
    Contains 1 PAS (PER-ARNT-SIM) domain.PROSITE-ProRule annotation
    Contains 1 Zn(2)-C6 fungal-type DNA-binding domain.PROSITE-ProRule annotation

    Phylogenomic databases

    OrthoDBiEOG70KGZB.

    Family and domain databases

    Gene3Di4.10.240.10. 1 hit.
    InterProiIPR000014. PAS.
    IPR013767. PAS_fold.
    IPR001138. Zn2-C6_fun-type_DNA-bd.
    [Graphical view]
    PfamiPF00989. PAS. 1 hit.
    PF00172. Zn_clus. 1 hit.
    [Graphical view]
    SMARTiSM00066. GAL4. 1 hit.
    SM00091. PAS. 1 hit.
    [Graphical view]
    SUPFAMiSSF55785. SSF55785. 1 hit.
    SSF57701. SSF57701. 1 hit.
    TIGRFAMsiTIGR00229. sensory_box. 1 hit.
    PROSITEiPS50112. PAS. 1 hit.
    PS00463. ZN2_CY6_FUNGAL_1. 1 hit.
    PS50048. ZN2_CY6_FUNGAL_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A6ZLH8-1 [UniParc]FASTAAdd to Basket

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    MCTPDENDYK TSTDPDTSAN TNHTLEKKKR KKRKNTNVAC VNCSRLHVSC    50
    EAKRPCLRCI SKGLTATCVD APRKKSKYLA GIPNRELPMN IQPDLPPRKI 100
    MIPIYNNSSN SSLNVNNMGE QQKFTSPQHI VHKAKFLSNA ADSEYSILSN 150
    IIYQDTLSNK IPIDILYSNT NSTSNSTIGN SSNNSPTGTN TSPEETEMEK 200
    IRQLYSEQRA NIPPHPYPSS NQNVYSILLG PNSAKIVASQ VNLFANHFPL 250
    VPVDSADNSL SFKRLLPRDP SEKSSQINWD SSINQYYLNS ETVTFPELAI 300
    PLKRRKNHLV SVSLESCSPD AANIKSNVEW EHSLRYSTPM EIYTSINAPF 350
    SHTPGFHHLL VYLKHRFNQQ DLVKMCRSIA EFRPIFIACS VTLTEEDMIF 400
    MEQCYQRTLL EYVKFIAQIG TPTCIWRRNG QISYVNEEFE ILCGWTREEL 450
    LNKMTFIVEI MDDESVRDYF KTLSKVAYRD FRGSEKMKVC RLLSPIKGKI 500
    IHCCCMWTLK RDVSGLPLMI LGNFMPILN 529
    Length:529
    Mass (Da):60,284
    Last modified:September 11, 2007 - v1
    Checksum:i65824A0CBA325ED8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAFW02000011 Genomic DNA. Translation: EDN64847.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAFW02000011 Genomic DNA. Translation: EDN64847.1 .

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    OrthoDBi EOG70KGZB.

    Family and domain databases

    Gene3Di 4.10.240.10. 1 hit.
    InterProi IPR000014. PAS.
    IPR013767. PAS_fold.
    IPR001138. Zn2-C6_fun-type_DNA-bd.
    [Graphical view ]
    Pfami PF00989. PAS. 1 hit.
    PF00172. Zn_clus. 1 hit.
    [Graphical view ]
    SMARTi SM00066. GAL4. 1 hit.
    SM00091. PAS. 1 hit.
    [Graphical view ]
    SUPFAMi SSF55785. SSF55785. 1 hit.
    SSF57701. SSF57701. 1 hit.
    TIGRFAMsi TIGR00229. sensory_box. 1 hit.
    PROSITEi PS50112. PAS. 1 hit.
    PS00463. ZN2_CY6_FUNGAL_1. 1 hit.
    PS50048. ZN2_CY6_FUNGAL_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: YJM789.

    Entry informationi

    Entry nameiERT1_YEAS7
    AccessioniPrimary (citable) accession number: A6ZLH8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 5, 2011
    Last sequence update: September 11, 2007
    Last modified: October 1, 2014
    This is version 38 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3