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A6ZKX7

- EDS1_YEAS7

UniProt

A6ZKX7 - EDS1_YEAS7

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Protein

Transcriptional regulatory protein EDS1

Gene
EDS1, SCY_0247
Organism
Saccharomyces cerevisiae (strain YJM789) (Baker's yeast)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi56 – 8530Zn(2)-C6 fungal-typeAdd
BLAST

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. sequence-specific DNA binding RNA polymerase II transcription factor activity Source: InterPro
  3. zinc ion binding Source: InterPro
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Transcriptional regulatory protein EDS1
Alternative name(s):
Expression dependent on SLT2 protein 1
Gene namesi
Name:EDS1
ORF Names:SCY_0247
OrganismiSaccharomyces cerevisiae (strain YJM789) (Baker's yeast)
Taxonomic identifieri307796 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000007060: Unassembled WGS sequence

Subcellular locationi

Nucleus Inferred

GO - Cellular componenti

  1. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 919919Transcriptional regulatory protein EDS1PRO_0000408010Add
BLAST

Interactioni

Subunit structurei

Binds DNA in a sequence-specific manner By similarity.

Structurei

3D structure databases

ProteinModelPortaliA6ZKX7.

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi913 – 9164Poly-Cys

Sequence similaritiesi

Phylogenomic databases

OrthoDBiEOG7X6M7G.

Family and domain databases

Gene3Di4.10.240.10. 1 hit.
InterProiIPR001138. Zn2-C6_fun-type_DNA-bd.
[Graphical view]
PfamiPF00172. Zn_clus. 1 hit.
[Graphical view]
SMARTiSM00066. GAL4. 1 hit.
[Graphical view]
SUPFAMiSSF57701. SSF57701. 1 hit.
PROSITEiPS00463. ZN2_CY6_FUNGAL_1. 1 hit.
PS50048. ZN2_CY6_FUNGAL_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A6ZKX7-1 [UniParc]FASTAAdd to Basket

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MSHHVPNLYG TPIRDPHERK RNSASMGEVN QSVSSRNCER GSEKGTKQRK    50
KASRACDQCR RKRIKCRFDK HTGVCQGCLE VGEKCQFIRV PLKRGPAKKR 100
ASVVSIEKFS SDNDPLQYRP RTHSYPMNSG NNYLPSLARN SSFPSISSLF 150
VPSITAQSQQ FVKVPYDDIK RRSSLATLGS DSSISTEFGG NYRLDENLNV 200
RQEGKDIVAK GMITPVEEMG ACSSNVRRQG SQSLPIQEQR ASPYINPFIS 250
GRSRLSSLSY TSEATTSEGN TQGKNQCMLT PNSVRSIEKE RLNSLTAGCP 300
NKKLGTDGRS DKWDKNSTWK PVYRSSNPSH PSTEKNVSLN QEASAKPLML 350
GTYRQFDATS FYKVLGIYYN FFHINFPVIP INKSKFTDML DPEKPNVIDE 400
IRQINNEIIQ CFKTALEVLV FCKIKQRRSS KSTKSWSRDS LCDFQKGLYY 450
IQNFNKCIAD CFQSLITIKP VLKQNSSVIP SRIKFIYFST IIVLNFILIL 500
AGEESSLLLG PSVGVFNEFQ AHKLFLPFEN TSPMLLLNSN EESGDEILDY 550
AVLFKRLYIL LNILDTLQSF RLGQPKLINL NFGSAIETYF SDKTGHNQVV 600
EKAPVALDNI LRNLKLGEFI TYFVLNRKSL QVNVPHHLLF TNQTDYGEFA 650
VEKGEHDNIA GKFETLLKKK EILIRKLLNI EQKNDHILEN CCNSDAEMKN 700
IGELVCSMIT LVSGILDSIT NMNAENSVDL DSKPLPNAYF AQDSEEELMS 750
PTQSITSNLA SEENTRCTTK DLMGTVSIFM LPMVEECYNI ISLIGPIPTT 800
LISLYIRNGN MAKGINDRIM TLSTALNELV QITALFNTLE PFRKNAHDRA 850
KRYYVSATSS TGCYESVMKS MYSGKCAASN ASNVAPSEEE NKKILKKFAD 900
IGWKLMDDSE LGCCCCFFN 919
Length:919
Mass (Da):103,375
Last modified:September 11, 2007 - v1
Checksum:i5398365D79AAA93D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AAFW02000011 Genomic DNA. Translation: EDN64646.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AAFW02000011 Genomic DNA. Translation: EDN64646.1 .

3D structure databases

ProteinModelPortali A6ZKX7.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

OrthoDBi EOG7X6M7G.

Family and domain databases

Gene3Di 4.10.240.10. 1 hit.
InterProi IPR001138. Zn2-C6_fun-type_DNA-bd.
[Graphical view ]
Pfami PF00172. Zn_clus. 1 hit.
[Graphical view ]
SMARTi SM00066. GAL4. 1 hit.
[Graphical view ]
SUPFAMi SSF57701. SSF57701. 1 hit.
PROSITEi PS00463. ZN2_CY6_FUNGAL_1. 1 hit.
PS50048. ZN2_CY6_FUNGAL_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: YJM789.

Entry informationi

Entry nameiEDS1_YEAS7
AccessioniPrimary (citable) accession number: A6ZKX7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 3, 2011
Last sequence update: September 11, 2007
Last modified: April 16, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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