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Protein

Transcriptional regulatory protein EDS1

Gene

EDS1

Organism
Saccharomyces cerevisiae (strain YJM789) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi56 – 8530Zn(2)-C6 fungal-typePROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Transcriptional regulatory protein EDS1
Alternative name(s):
Expression dependent on SLT2 protein 1
Gene namesi
Name:EDS1
ORF Names:SCY_0247
OrganismiSaccharomyces cerevisiae (strain YJM789) (Baker's yeast)
Taxonomic identifieri307796 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000007060 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 919919Transcriptional regulatory protein EDS1PRO_0000408010Add
BLAST

Interactioni

Subunit structurei

Binds DNA in a sequence-specific manner.By similarity

Structurei

3D structure databases

ProteinModelPortaliA6ZKX7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi913 – 9164Poly-Cys

Sequence similaritiesi

Contains 1 Zn(2)-C6 fungal-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

OrthoDBiEOG7X6M7G.

Family and domain databases

Gene3Di4.10.240.10. 1 hit.
InterProiIPR001138. Zn2-C6_fun-type_DNA-bd.
[Graphical view]
PfamiPF00172. Zn_clus. 1 hit.
[Graphical view]
SMARTiSM00066. GAL4. 1 hit.
[Graphical view]
SUPFAMiSSF57701. SSF57701. 1 hit.
PROSITEiPS00463. ZN2_CY6_FUNGAL_1. 1 hit.
PS50048. ZN2_CY6_FUNGAL_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A6ZKX7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSHHVPNLYG TPIRDPHERK RNSASMGEVN QSVSSRNCER GSEKGTKQRK
60 70 80 90 100
KASRACDQCR RKRIKCRFDK HTGVCQGCLE VGEKCQFIRV PLKRGPAKKR
110 120 130 140 150
ASVVSIEKFS SDNDPLQYRP RTHSYPMNSG NNYLPSLARN SSFPSISSLF
160 170 180 190 200
VPSITAQSQQ FVKVPYDDIK RRSSLATLGS DSSISTEFGG NYRLDENLNV
210 220 230 240 250
RQEGKDIVAK GMITPVEEMG ACSSNVRRQG SQSLPIQEQR ASPYINPFIS
260 270 280 290 300
GRSRLSSLSY TSEATTSEGN TQGKNQCMLT PNSVRSIEKE RLNSLTAGCP
310 320 330 340 350
NKKLGTDGRS DKWDKNSTWK PVYRSSNPSH PSTEKNVSLN QEASAKPLML
360 370 380 390 400
GTYRQFDATS FYKVLGIYYN FFHINFPVIP INKSKFTDML DPEKPNVIDE
410 420 430 440 450
IRQINNEIIQ CFKTALEVLV FCKIKQRRSS KSTKSWSRDS LCDFQKGLYY
460 470 480 490 500
IQNFNKCIAD CFQSLITIKP VLKQNSSVIP SRIKFIYFST IIVLNFILIL
510 520 530 540 550
AGEESSLLLG PSVGVFNEFQ AHKLFLPFEN TSPMLLLNSN EESGDEILDY
560 570 580 590 600
AVLFKRLYIL LNILDTLQSF RLGQPKLINL NFGSAIETYF SDKTGHNQVV
610 620 630 640 650
EKAPVALDNI LRNLKLGEFI TYFVLNRKSL QVNVPHHLLF TNQTDYGEFA
660 670 680 690 700
VEKGEHDNIA GKFETLLKKK EILIRKLLNI EQKNDHILEN CCNSDAEMKN
710 720 730 740 750
IGELVCSMIT LVSGILDSIT NMNAENSVDL DSKPLPNAYF AQDSEEELMS
760 770 780 790 800
PTQSITSNLA SEENTRCTTK DLMGTVSIFM LPMVEECYNI ISLIGPIPTT
810 820 830 840 850
LISLYIRNGN MAKGINDRIM TLSTALNELV QITALFNTLE PFRKNAHDRA
860 870 880 890 900
KRYYVSATSS TGCYESVMKS MYSGKCAASN ASNVAPSEEE NKKILKKFAD
910
IGWKLMDDSE LGCCCCFFN
Length:919
Mass (Da):103,375
Last modified:September 11, 2007 - v1
Checksum:i5398365D79AAA93D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFW02000011 Genomic DNA. Translation: EDN64646.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFW02000011 Genomic DNA. Translation: EDN64646.1.

3D structure databases

ProteinModelPortaliA6ZKX7.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

OrthoDBiEOG7X6M7G.

Family and domain databases

Gene3Di4.10.240.10. 1 hit.
InterProiIPR001138. Zn2-C6_fun-type_DNA-bd.
[Graphical view]
PfamiPF00172. Zn_clus. 1 hit.
[Graphical view]
SMARTiSM00066. GAL4. 1 hit.
[Graphical view]
SUPFAMiSSF57701. SSF57701. 1 hit.
PROSITEiPS00463. ZN2_CY6_FUNGAL_1. 1 hit.
PS50048. ZN2_CY6_FUNGAL_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: YJM789.

Entry informationi

Entry nameiEDS1_YEAS7
AccessioniPrimary (citable) accession number: A6ZKX7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 3, 2011
Last sequence update: September 11, 2007
Last modified: January 7, 2015
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.